Zobrazeno 1 - 10
of 65
pro vyhledávání: '"In silico validation"'
Autor:
Annadurai Vinothkanna, Xiang Shi‐Liang, Durairaj Karthick Rajan, Ragothaman Prathiviraj, Soundarapandian Sekar, Shubing Zhang, Bo Wang, Zhu Liu, Ai‐Qun Jia
Publikováno v:
Food Frontiers, Vol 5, Iss 4, Pp 1476-1511 (2024)
Abstract People with diabetes mellitus (DM) and hyperglycemia are linked with cancer risk. Diabetes and cancer have been corroborated by high morbidity and mortality rates. Studies revealed that elevated levels of insulin secretions trigger insulin
Externí odkaz:
https://doaj.org/article/8ab524b3882b42e58ecf0679f531b3e5
Autor:
Mehrad Jaloli, Marzia Cescon
Publikováno v:
BioMedInformatics, Vol 3, Iss 2, Pp 422-433 (2023)
In this study, we propose a closed-loop insulin administration framework for multiple daily injection (MDI) treatment using a reinforcement learning (RL) agent for insulin bolus therapy. The RL agent, based on the soft actor–critic (SAC) algorithm,
Externí odkaz:
https://doaj.org/article/6abfaedb95be40ffb8c7eae1efd9c3a7
Publikováno v:
IEEE Access, Vol 9, Pp 105756-105775 (2021)
Controlling blood glucose levels in diabetic patients is important for managing their health and quality of life. Several algorithms based on model predictive control and reinforcement learning (RL) have been proposed so far, most of which use prior
Externí odkaz:
https://doaj.org/article/fb537d895dd94aea86568c93a7145cc4
Autor:
Rahim Gholipoorfeshkecheh, Swati Agarwala, Kavya G, Santhosh Krishnappa, Mysore R. Savitha, Nallur B. Ramachandra
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Homozygosity mapping is an efficient gene mapping method applicable to recessive disorders. It can detect homozygous segments of identical haplotype structures shared at a higher frequency among ventricular septal defect (VSD) and
Externí odkaz:
https://doaj.org/article/7d0add788ac04f9487605ac060d6e936
Autor:
Pan Chen, Hongliang Yao, Qing Yuan, Panlin Li, Xinning Wang, Weiwei Su, Yonggang Wang, Peibo Li
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Oral ulcer diseases are complex inflammatory diseases caused by multi-factors, which severely impact patient quality of life. Kouyanqing Granule (KYQG) has been used to treat inflammatory diseases of the mouth and throat, includin
Externí odkaz:
https://doaj.org/article/8c888c3edab34e368cc13ccdb086d1e9
Autor:
Yasmmin Côrtes Martins, Artur Ziviani, Marisa Fabiana Nicolás, Ana Tereza Ribeiro de Vasconcelos
Publikováno v:
Frontiers in Bioinformatics, Vol 1 (2021)
Predicting the physical or functional associations through protein-protein interactions (PPIs) represents an integral approach for inferring novel protein functions and discovering new drug targets during repositioning analysis. Recent advances in hi
Externí odkaz:
https://doaj.org/article/54c332ed41694f4580bdbcfb74f5176f
Akademický článek
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Akademický článek
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Autor:
Alessandro Borri, Giordano Pola, Pierdomenico Pepe, Maria Domenica Di Benedetto, Pasquale Palumbo
Publikováno v:
IEEE Transactions on Control Systems Technology. 30:2131-2146
Diabetes is a widespread disease characterized by chronic hyperglycemia so that diabetic individuals usually require the administration of exogenous insulin for survival. As a consequence, in the context of the so-called artificial pancreas, many glu
Autor:
Cescon, Mehrad Jaloli, Marzia
Publikováno v:
BioMedInformatics; Volume 3; Issue 2; Pages: 422-433
In this study, we propose a closed-loop insulin administration framework for multiple daily injection (MDI) treatment using a reinforcement learning (RL) agent for insulin bolus therapy. The RL agent, based on the soft actor–critic (SAC) algorithm,