Zobrazeno 1 - 2
of 2
pro vyhledávání: '"In silico models, oral biopharmaceutics"'
Autor:
O'Shea, Joseph P. a, ⁎, Augustijns, Patrick b, Brandl, Martin c, Brayden, David J. d, Brouwers, Joachim b, Griffin, Brendan T. a, Holm, René c, Jacobsen, Ann-Christin c, e, Lennernäs, Hans f, Vinarov, Zahari b, g, O'Driscoll, Caitriona M. a
Publikováno v:
In European Journal of Pharmaceutical Sciences 1 March 2022 170
Autor:
Joseph P. O'Shea, Patrick Augustijns, Martin Brandl, David J. Brayden, Joachim Brouwers, Brendan T. Griffin, René Holm, Ann-Christin Jacobsen, Hans Lennernäs, Zahari Vinarov, Caitriona M. O'Driscoll
Publikováno v:
O'Shea, J P, Augustijns, P, Brandl, M, Brayden, D J, Brouwers, J, Griffin, B T, Holm, R, Jacobsen, A-C, Lennernäs, H, Vinarov, Z & O'Driscoll, C M 2022, ' Best practices in current models mimicking drug permeability in the gastrointestinal tract-an UNGAP review ', European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, vol. 170, 106098, pp. 106098 . https://doi.org/10.1016/j.ejps.2021.106098
The absorption of orally administered drug products is a complex, dynamic process, dependant on a range of biopharmaceutical properties; notably the aqueous solubility of a molecule, stability within the gastrointestinal tract (GIT) and permeability.