Zobrazeno 1 - 10
of 1 418
pro vyhledávání: '"In silico clinical trials"'
Autor:
Pathmanathan, Pras1 (AUTHOR) pras.pathmanathan@fda.hhs.gov, Aycock, Kenneth1 (AUTHOR), Badal, Andreu1 (AUTHOR), Bighamian, Ramin1 (AUTHOR), Bodner, Jeff2 (AUTHOR), Craven, Brent A.1 (AUTHOR), Niederer, Steven3,4 (AUTHOR)
Publikováno v:
PLoS Computational Biology. 8/8/2024, Vol. 20 Issue 8, p1-32. 32p.
Publikováno v:
In Computer Methods and Programs in Biomedicine December 2023 242
Autor:
Camps, Julia, Berg, Lucas Arantes, Wang, Zhinuo Jenny, Sebastian, Rafael, Riebel, Leto Luana, Doste, Ruben, Zhou, Xin, Sachetto, Rafael, Coleman, James, Lawson, Brodie, Grau, Vicente, Burrage, Kevin, Bueno-Orovio, Alfonso, Weber, Rodrigo, Rodriguez, Blanca
Cardiac in silico clinical trials can virtually assess the safety and efficacy of therapies using human-based modelling and simulation. These technologies can provide mechanistic explanations for clinically observed pathological behaviour. Designing
Externí odkaz:
http://arxiv.org/abs/2306.13740
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Camps, Julia a, ⁎, 1, Berg, Lucas Arantes a, 1, Wang, Zhinuo Jenny a, Sebastian, Rafael c, Riebel, Leto Luana a, Doste, Ruben a, Zhou, Xin a, Sachetto, Rafael d, Coleman, James a, Lawson, Brodie e, Grau, Vicente a, Burrage, Kevin a, e, Bueno-Orovio, Alfonso a, Weber dos Santos, Rodrigo b, Rodriguez, Blanca a
Publikováno v:
In Medical Image Analysis May 2024 94
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
A clinical trial is an essential step in drug development, which is often costly and time-consuming. In silico trials are clinical trials conducted digitally through simulation and modeling as an alternative to traditional clinical trials. AI-enabled
Externí odkaz:
http://arxiv.org/abs/2209.09023
Autor:
Pras Pathmanathan, Kenneth Aycock, Andreu Badal, Ramin Bighamian, Jeff Bodner, Brent A Craven, Steven Niederer
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 8, p e1012289 (2024)
In silico clinical trials (ISCTs) are an emerging method in modeling and simulation where medical interventions are evaluated using computational models of patients. ISCTs have the potential to provide cost-effective, time-efficient, and ethically fa
Externí odkaz:
https://doaj.org/article/883fb3cce66341adb9093faef05a5529
Autor:
Vettoretti, Martina ⁎, Drecogna, Martina, Del Favero, Simone, Facchinetti, Andrea, Sparacino, Giovanni
Publikováno v:
In Computer Methods and Programs in Biomedicine October 2023 240
Autor:
Kenneth I. Aycock, Tom Battisti, Ashley Peterson, Jiang Yao, Steven Kreuzer, Claudio Capelli, Sanjay Pant, Pras Pathmanathan, David M. Hoganson, Steve M. Levine, Brent A. Craven
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Computational models of patients and medical devices can be combined to perform an in silico clinical trial (ISCT) to investigate questions related to device safety and/or effectiveness across the total product life cycle. ISCTs can potentially accel
Externí odkaz:
https://doaj.org/article/ccb778af6883417ab746f816059b55be