Zobrazeno 1 - 9
of 9
pro vyhledávání: '"In Sug O-Sullivan"'
Autor:
IN SUG O-SULLIVAN, SUMIT BHATTACHARYYA, CHONG WEE LIEW, SAM M. LEE, JOSE CORDOBA-CHACON, RACHEL J. PERRY, GERALD I. SHULMAN, TERRY UNTERMAN
Publikováno v:
Diabetes. 71
FoxO1 is a major target of insulin action and regulates expression of ATGL and its inhibitor, G0S2, in the liver (Cell Rep 15:349, 2016) . Here, we asked whether ATGL mediates effects of FoxO1 in liver-specific insulin receptor knockout (LIRKO) mice.
Autor:
Thomas J. Park, Jeffrey S. Kroin, Daniel T. Applegate, Bronislaw Pytowski, Richard Ripper, Xin Li, In Sug O-Sullivan, Andre J. van Wijnen, Gina Votta-Velis, Ranjan Kc, Hee Jeong Im, Vaskar Das
Publikováno v:
Gene Reports. 11:94-100
Osteoarthritis (OA) is a painful and debilitating disease. A striking feature of OA is the dramatic increase in vascular endothelial growth factor (VEGF) levels and in new blood vessel formation in the joints, both of which correlate with the severit
Autor:
Atiyayein A. Wallace, Sujun Qiu, Richard Ripper, Fackson Mwale, Hee Jeong Im, In Sug O-Sullivan, Gina Votta-Velis, Bingqian Zhu, Andre J. van Wijnen, Jeffrey S. Kroin, Vaskar Das, Changgui Shi, Lan Zhao, Jun Lu, Xin Li, Ranjan Kc, Ming-liang Ji, Wen Yuan
Publikováno v:
Journal of Cellular Physiology. 233:6589-6602
Discogenic low back pain (DLBP) is extremely common and costly. Effective treatments are lacking due to DLBP's unknown pathogenesis. Currently, there are no in vivo mouse models of DLBP, which restricts research in this field. The aim of this study w
Autor:
So Young Bu, In Sug O-Sullivan, Salmaan A. Khan, Wenwei Zhang, Douglas G. Mashek, Zakaria Sibai, Christopher B. Newgard, Terry G. Unterman, Olga Ilkayeva, Mara T. Mashek
Publikováno v:
Cell Reports, Vol 15, Iss 2, Pp 349-359 (2016)
FoxO proteins are major targets of insulin action. Adipose triacylglycerol (TAG) lipase mediates the first step in TAG hydrolysis and FoxO1 stimulates ATGL expression in adipose tissue. Here, we report that FoxO1 also stimulates ATGL and suppresses e
Publikováno v:
Vaccine. 28:7757-7763
This study describes the immunotherapeutic properties of vaccines that encode tumor-associated calcium signal transducer-1 (Trop-1), a newly identified breast cancer antigen, in mice with breast cancer. Previously we found that Trop-1 was over-expres
Publikováno v:
Journal of Immunotherapy. 29:261-273
Breast cancer cells express an array of weakly immunogenic tumor-associated antigens (TAAs). Under appropriate circumstances, immunity to breast cancer can be induced, with potential benefits for patients with the disease. Here, we report a new cell-
Antigenic differences between normal and malignant cells of the cancer patient form the rationale for clinical immunotherapeutic strategies. Because the antigenic phenotype of neoplastic cells varies widely among different cells within the same malig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a35525df1063252838c2be2d51d8bd
https://europepmc.org/articles/PMC1646255/
https://europepmc.org/articles/PMC1646255/
Publikováno v:
International journal of cancer. 119(2)
We report a new vaccination strategy for squamous cell carcinoma (SCC). The vaccine was prepared by transfer of unfractionated DNA-fragments (25 kb) from squamous carcinoma cells (KLN205, DBA/2 origin (H-2(d))) into LM mouse fibroblasts (C3H/He origi
Publikováno v:
International journal of cancer. 118(11)
Here, we describe the enhanced benefits of treating a highly aggressive breast cancer in mice with a combination of paclitaxel and immunization with a unique DNA-based cell vaccine. An adenocarcinoma was isolated from a spontaneous neoplasm that aros