Zobrazeno 1 - 10
of 1 438
pro vyhledávání: '"In Kyu Kwon"'
Autor:
Inyoung Yang, Na-Hee Jeong, Young-Ae Choi, Taeg Kyu Kwon, Soyoung Lee, Dongwoo Khang, Sang-Hyun Kim
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116911- (2024)
Atopic dermatitis (AD) is a globally increasing chronic inflammatory skin disease with limited and potentially side-effect-prone treatment options. Monotropein is the predominant iridoid glycoside in Morinda officinalis How roots, which has previousl
Externí odkaz:
https://doaj.org/article/a8c634635422445e81a3728d7256a32d
Autor:
Seul Gi Lee, Seon Min Woo, Seung Un Seo, Chan-Hyeong Lee, Moon-Chang Baek, Se Hwan Jang, Zee Yong Park, Simmyung Yook, Ju-Ock Nam, Taeg Kyu Kwon
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 2, Pp 383-394 (2024)
Abstract M2-like tumor-associated macrophages (TAMs) are risk factors for cancer progression and metastasis. However, the mechanisms underlying their polarization are still not fully understood. Although cathepsin D (Cat D) has been reported as a pro
Externí odkaz:
https://doaj.org/article/3b2f5abfaf9c44249e26630cf6332b95
Autor:
Dong-Hwi Kim, Da-Yoon Kim, Kyu-Sung Kim, Sang-Hoon Han, Hyeon-Jeong Go, Jae-Hyeong Kim, Kyu-Beom Lim, Dong-Hun Lee, Joong-Bok Lee, Seung-Yong Park, Chang-Seon Song, Sang-Won Lee, Yang-Kyu Choi, Yeun-Kyung Shin, Oh-Kyu Kwon, Do-Geun Kim, In-Soo Choi
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 11, Pp 2275-2284 (2023)
SARS-CoV-2 induces illness and death in humans by causing systemic infections. Evidence suggests that SARS-CoV-2 can induce brain pathology in humans and other hosts. In this study, we used a canine transmission model to examine histopathologic chang
Externí odkaz:
https://doaj.org/article/dfbd1cf3966c49429c7a52249ffde912
Publikováno v:
Cell Death and Disease, Vol 14, Iss 6, Pp 1-11 (2023)
Abstract The Raptor signaling pathway is a critical point of intervention in the invasion and progression of cancer. The non-receptor tyrosine kinase Src-mediated phosphorylation of OTUB1-Y26 plays a critical role in Raptor stabilization, whereas cat
Externí odkaz:
https://doaj.org/article/23beb553ffe2487da9ce7ba88a4a4649
Autor:
Tayaba Ismail, Hyun-Kyung Lee, Hongchan Lee, Youni Kim, Eunjeong Kim, Jun-Yeong Lee, Kee-Beom Kim, Hong-Yeoul Ryu, Dong-Hyung Cho, Taeg Kyu Kwon, Tae Joo Park, Taejoon Kwon, Hyun-Shik Lee
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 269, Iss , Pp 115820- (2024)
Perfluorooctanesulfonate (PFOS) is a ubiquitous environmental pollutant associated with increasing health concerns and environmental hazards. Toxicological analyses of PFOS exposure are hampered by large interspecies variations and limited studies on
Externí odkaz:
https://doaj.org/article/d257ce8b07ab4f1697495e2f06ce8165
Publikováno v:
PLOS Digital Health, Vol 2, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/f43fe341e36e4d0a8269556c24528515
Publikováno v:
Gut and Liver, Vol 17, Iss 3, Pp 456-465 (2023)
Background/Aims: We explored whether high sodium intake, assessed by urinary excretion, determines the risk of sarcopenia and nonalcoholic fatty liver disease (NAFLD). Methods: We analyzed 10,036 adult participants with normal kidney function from th
Externí odkaz:
https://doaj.org/article/7fb3b1b573894f5084bebf02fdbba8a0
Autor:
Seul Gi Lee, Jongbeom Chae, Seon Min Woo, Seung Un Seo, Ha-Jeong Kim, Sang-Yeob Kim, David D. Schlaepfer, In-San Kim, Hee-Sae Park, Taeg Kyu Kwon, Ju-Ock Nam
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 3, Pp 520-531 (2023)
Fat metabolism: protecting against obesity-related metabolic disorders Studying a protein called TGFBI, which regulates adipose expansion, may help the development of new approaches to protect against obesity and related metabolic disorders such as t
Externí odkaz:
https://doaj.org/article/553128a2c59e4034b9f3735a4d3e3a37
Autor:
Jae-Ho Lee, Sun Hee Lee, Eun-Ho Lee, Jeong-Yong Cho, Dae-Kyu Song, Young Jae Lee, Taeg Kyu Kwon, Byung-Chul Oh, Kae Won Cho, Timothy F. Osborne, Tae-Il Jeon, Seung-Soon Im
Publikováno v:
Journal of Advanced Research, Vol 45, Iss , Pp 1-13 (2023)
Introduction: Sterol regulatory element binding protein (SREBP) cleavage-associating protein (SCAP) is a sterol-regulated escort protein that translocates SREBPs from the endoplasmic reticulum to the Golgi apparatus, thereby activating lipid metaboli
Externí odkaz:
https://doaj.org/article/fa480bf32fcc444ab2cfb2d2d12b298f
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5746 (2024)
4-O-Methyl-ascochlorin (MAC), a derivative of the prenyl–phenol antibiotic ascochlorin extracted from the fungus Ascochyta viciae, shows anticarcinogenic effects on various cancer cells. 5-Fluorouracil (5-FU) is used to treat colorectal cancer (CRC
Externí odkaz:
https://doaj.org/article/a01136acc77c41acb2b61b4ce9324278