Zobrazeno 1 - 10
of 22
pro vyhledávání: '"In Kiu Kwon"'
Autor:
Kyung-Bon Lee, Ki-Eun Park, In-Kiu Kwon, Swamy K Tripurani, Keun Jung Kim, Ji Hye Lee, Koji Niwa, Min Kyu Kim
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78260 (2013)
This study investigated the development of rat oocytes in vitro and in vivo following intracytoplasmic injection of heads from spermatozoa heat-dried at 50°C for 8 h and stored at 4°C in different gas phases. Sperm membrane and chromosome are damag
Externí odkaz:
https://doaj.org/article/bde77c711d2c4469913f0ced659fd0f8
Autor:
Subbaramiah Sridhar, Darren D. Browning, Kebin Liu, Franz Hofmann, Rui Wang, Bianca N. Islam, Nagendra Singh, In-Kiu Kwon
Publikováno v:
Cell Death & Differentiation. 21:427-437
Analysis of knockout animals indicates that 3',5'cyclic guanosine monophosphate (cGMP) has an important role in gut homeostasis but the signaling mechanism is not known. The goals of this study were to test whether increasing cGMP could affect colon
Autor:
R. Wang, Nickolai O. Dulin, Darren D. Browning, H. Shuang, Muthusamy Thangaraju, Kebin Liu, In-Kiu Kwon, Roderick H. Dashwood, Vadivel Ganapathy
Publikováno v:
Oncogene. 29:3423-3434
Activation of cGMP-dependent protein kinase (PKG) has anti-tumor effects in colon cancer cells but the mechanisms are not fully understood. This study has examined the regulation of beta-catenin/TCF signaling, as this pathway has been highlighted as
Publikováno v:
Future Medicinal Chemistry. 2:65-80
In recent years, several antitumor signaling pathways mediated by the cGMP-dependent protein kinases have been identified in colon cancer cells. This review aims to present the mounting evidence in favor of cGMP/protein kinase G (PKG) signaling as a
Publikováno v:
Biology of Reproduction. 71:1430-1436
The fertilization of pig oocytes following intracytoplasmic injection of freeze-dried spermatozoa was evaluated. Activation and male pronuclear (MPN) formation were better in oocytes injected with isolated freeze-dried sperm heads than whole freeze-d
Autor:
Min Kyu Kim, Keun Jung Kim, In-Kiu Kwon, Swamy K. Tripurani, Ji Hye Lee, Ki-Eun Park, Koji Niwa, Kyung-Bon Lee
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 11, p e78260 (2013)
PLoS ONE, Vol 8, Iss 11, p e78260 (2013)
This study investigated the development of rat oocytes in vitro and in vivo following intracytoplasmic injection of heads from spermatozoa heat-dried at 50°C for 8 h and stored at 4°C in different gas phases. Sperm membrane and chromosome are damag
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(38)
Endocannabinoids play essential roles in synaptic plasticity; thus, their dysfunction often causes impairments in memory or cognition. However, it is not well understood whether deficits in the endocannabinoid system account for the cognitive symptom
Autor:
Kebin Liu, Renee Bozard, In Kiu Kwon, Troy A. Baudino, Muthusamy Thangaraju, Nikhil Prakash, Darren D. Browning, Rui Wang, Zheng Dong
Publikováno v:
Cancer. 117(23)
BACKGROUND: Type 1 cyclic 3′,5′-guanosine monophosphate-dependent protein kinase (PKG) has recently been reported to inhibit tumor growth and angiogenesis. These effects suggest that PKG activation may have therapeutic value for colon cancer trea
Autor:
Darren D. Browning, Patricia V. Schoenlein, Muthusmy Thangaraju, Nickolai O. Dulin, In Kiu Kwon, Jennifer N. Delk, Franklin G. Berger, Kebin Liu, Vadivel Ganapathy
Publikováno v:
Cancer. 112(7)
BACKGROUND Type 1 cyclic guanosine monophosphate (cGMP)-dependent protein kinase (PKG) reportedly has exhibited antitumor properties, and its expression is down-regulated in many tumors. METHODS The authors recently demonstrated that PKG re-expressio
Publikováno v:
The Journal of reproduction and development. 51(1)
This study was designed to investigate whether the partial removal of cytoplasmic lipid from immature pig oocytes prior to vitrification had any positive effects on subsequent maturation, fertilization and early development. Oocytes at the germinal v