Zobrazeno 1 - 10
of 3 720
pro vyhledávání: '"In Hee Shin"'
Autor:
Ji Ye Lee, Min Kyoung Lee, Hyun Kyung Lim, Chang Yoon Lee, Jin Yong Sung, Jung Hyun Yoon, Soo Yeon Hahn, Jung Hee Shin, Ji-hoon Kim, So Lyung Jung, Sae Rom Chung, Jung Hwan Baek, Dong Gyu Na
Publikováno v:
Journal of the Korean Society of Radiology, Vol 85, Iss 6, Pp 1060-1082 (2024)
Active surveillance (AS) has been widely adopted as an alternative to immediate surgery owing to the indolent nature and favorable outcomes of papillary thyroid microcarcinoma (PTMC). AS is generally recommended for tumors measuring ≤1 cm without
Externí odkaz:
https://doaj.org/article/f6a05d33106d4744a456cdb75efd1d6a
Autor:
Yiyu Hong, Junsu Ha, Jaemin Sim, Chae Jo Lim, Kwang-Seok Oh, Ramakrishnan Chandrasekaran, Bomin Kim, Jieun Choi, Junsu Ko, Woong-Hee Shin, Juyong Lee
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract We introduce an advanced model for predicting protein–ligand interactions. Our approach combines the strengths of graph neural networks with physics-based scoring methods. Existing structure-based machine-learning models for protein–liga
Externí odkaz:
https://doaj.org/article/7e379bec9c5c44859c5da2655445f68a
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Gouty inflammation, caused by uric acid crystal deposition, primarily affects tissues around the toe joints and triggers potent inflammatory responses. Current treatments focus on alleviating inflammation and pain using pharmaceutical agents
Externí odkaz:
https://doaj.org/article/4796820551324b9ea077d302f5981553
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Structure-based virtual screening (SBVS) is a crucial computational approach in drug discovery, but its performance is sensitive to structural variations. Kinases, which are major drug targets, exemplify this challenge due to active site con
Externí odkaz:
https://doaj.org/article/e7c8586721a4473a9c3eff8160c89e51
Autor:
Vipada Khaowroongrueng, Kuk Hui Son, Sang‐Min Lee, JiYeon Lee, Chun‐Gon Park, Seok In Lee, Dongseong Shin, Kwang‐Hee Shin
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 10, Pp 1682-1692 (2024)
Abstract Sufentanil is frequently used as an anesthetic agent in cardiac surgery owing to its cardiovascular safety and favorable pharmacokinetics. However, the pharmacokinetics profiles of sufentanil in patients undergoing cardiopulmonary bypass (CP
Externí odkaz:
https://doaj.org/article/dcbf466ea0a74a669ff319a08c7f1d07
M1 macrophage-derived exosomal microRNA-29c-3p suppresses aggressiveness of melanoma cells via ENPP2
Autor:
Byoungha An, Cheol-Hee Shin, Jae Won Kwon, Na Ly Tran, A Hui Kim, Hyeyeon Jeong, Sang-Heon Kim, Kwideok Park, Seung Ja Oh
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-20 (2024)
Abstract In the tumor microenvironment, macrophages play crucial roles resulting in tumor suppression and progression, depending on M1 and M2 macrophages, respectively. In particular, macrophage-derived exosomes modulate the gene expression of cancer
Externí odkaz:
https://doaj.org/article/f9436e5e810f4928a1f7ec29de84efd0
Autor:
Dokyun Kim, Da Young Kang, Min Hyuk Choi, Jun Sung Hong, Hyun Soo Kim, Young Ree Kim, Young Ah Kim, Young Uh, Kyeong Seob Shin, Jeong Hwan Shin, Soo Hyun Kim, Jong Hee Shin, Seok Hoon Jeong
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background This study analyzed the genetic traits and fitness costs of vancomycin-resistant Enterococcus faecium (VREfm) blood isolates carrying Tn1546-type transposons harboring the vanA operon. Methods All E. faecium blood isolates were co
Externí odkaz:
https://doaj.org/article/1e0c76c140254cfe9e5f6b9af0dc5ba4
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Telomerase reverse transcriptase (TERT) promoter mutations are associated with tumor aggressiveness. This study aimed to demonstrate the ultrasonographic (US) features of TERT promoter-mutated follicular thyroid cancer (FTC) and evaluate the
Externí odkaz:
https://doaj.org/article/c97471705e084f8b9bff977231bdc64f
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 287, Iss , Pp 117307- (2024)
Ivermectin (IVM) is a widely used anthelmintic in human and veterinary medicine. However, the increasing use of IVM raises concerns about its potential harm against non-targeted organisms. This study demonstrates a novel mechanism where IVM triggers
Externí odkaz:
https://doaj.org/article/5bb2faa92d3e4879bbf59994c663b307
Autor:
In Ji Hwang, Yong Jun Kwon, Ha Jin Lim, Ki Ho Hong, Hyukmin Lee, Dongeun Yong, Eun Jeong Won, Seung A. Byun, Ga Yeong Lee, Soo Hyun Kim, Eun Song Song, Jong Hee Shin
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT The clonal transmission of fluconazole-resistant Candida glabrata isolates within hospitals has seldom been analyzed by whole-genome sequencing (WGS). We performed WGS on 79 C. glabrata isolates, comprising 31 isolates from three premature i
Externí odkaz:
https://doaj.org/article/b8b239a00da74581b1aaba81e0189932