Induced pluripotent stem cell-derived vascular networks to screen nano–bio interactions

Autor: Helena Vazão, Vitor Francisco, Lino Ferreira, Patrícia R. Pitrez, Lara Carvalho, Akhilesh Rai, Josephine Blersch, Leonor Saúde, Mário Grãos, Inês Honório, Luís M.B.B. Estronca, Xavier Nissan, Ulrich Simon

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

© The Royal Society of Chemistry, 2021. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0)
The vascular bioactivity/safety of nanomaterials is typically evaluated by animal testing, which is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8fe63c3b94befa39bad38587999f377
https://doi.org/10.1039/d0nh00550a

High-throughput identification of small molecules that affect human embryonic vascular development

Autor: Margreet R. de Vries, Carlos Filipe Pereira, Dimitri Papatsenko, Inês Honório, Daniel B.F. Saris, Helena Vazão, Nadia Mercader, Lino Ferreira, Hugo Fernandes, Tânia Barata, Ricardo Costa, Ali Khademhosseini, Paul H.A. Quax, Patrícia R. Pitrez, S.C. Rosa, Rui Benedito

Publikováno v: Proceedings of the National Academy of Sciences, 114(15), E3022-E3031
Proceedings of the National Academy of Sciences of the United States of America, 114(15), E3022-E3031. National Academy of Sciences

Birth defects, which are in part caused by exposure to environmental chemicals and pharmaceutical drugs, affect 1 in every 33 babies born in the United States each year. The current standard to screen drugs that affect embryonic development is based

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310abfaa13025b3dfe6636a7b343a92a
https://hdl.handle.net/1887/95231