Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Inês G Mollet"'
Autor:
Anna Wendt, Inês G Mollet, Anki Knutsson, Victor S Bolmgren, Anna Hultgårdh-Nilsson, Maria F Gomez, Lena Eliasson
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170498 (2017)
Type 2 diabetic patients suffer from insulin resistance and reduced insulin secretion. Osteopontin (OPN), a versatile protein expressed in several tissues throughout the body including the islets of Langerhans, has previously been implicated in the d
Externí odkaz:
https://doaj.org/article/e33954fccd744085be5ecb853940ceef
Autor:
Inês G Mollet, Dilipkumar Patel, Fatima S Govani, Adam Giess, Koralia Paschalaki, Manikandan Periyasamy, Elaine C Lidington, Justin C Mason, Michael D Jones, Laurence Game, Simak Ali, Claire L Shovlin
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0147990 (2016)
BACKGROUND:Spontaneous reports from patients able to report vascular sequelae in real time, and recognition that serum non transferrin bound iron may reach or exceed 10μmol/L in the blood stream after iron tablets or infusions, led us to hypothesize
Externí odkaz:
https://doaj.org/article/2124d7e947f44e82b62022015bd7087c
Autor:
Claire L Shovlin, Gillian Angus, Richard A Manning, Grace N Okoli, Fatima S Govani, Kay Elderfield, Graeme M Birdsey, Inês G Mollet, Michael A Laffan, Francesco A Mauri
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9154 (2010)
Coagulation factor VIII (FVIII) deficiency leads to haemophilia A. Conversely, elevated plasma levels are a strong predictor of recurrent venous thromboemboli and pulmonary hypertension phenotypes in which in situ thromboses are implicated. Extrahepa
Externí odkaz:
https://doaj.org/article/1ee1cca344154c9baa88b450f4f448dd
Autor:
João Pedro Marto, Ana Sofia Carvalho, Inês G. Mollet, Marcelo Mendonça, Manuel Salavisa, Bruna Meira, Marco Fernandes, Filipa Serrazina, Gonçalo Cabral, Rita Ventura, André Sobral‐Pinho, Hans C. Beck, Helena L. A. Vieira, Miguel Viana‐Baptista, Rune Matthiesen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 22 (2023)
Background Blood biomarkers are a potential tool for early stroke diagnosis. We aimed to perform a pilot and exploratory study on untargeted blood biomarkers in patients with suspected stroke by using mass spectrometry analysis. Methods and Results T
Externí odkaz:
https://doaj.org/article/14e84b612146400794cafcbe834cc7cf
Autor:
Inês G. Mollet, Helena L. A. Vieira, Marcelo Mendonça, João Pedro Marto, Miguel Viana Baptista
Publikováno v:
Molecular Neurobiology
Stroke is one of the main causes of neurological disability worldwide and the second cause of death in people over 65 years old, resulting in great economic and social burden. Ischemic stroke accounts for 85% of total cases, and the approved therapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d608a11d2dd164f888ee5a126a65f71
https://doi.org/10.1007/s12035-021-02585-6
https://doi.org/10.1007/s12035-021-02585-6
Autor:
Maria E Bernabeu-Herrero, Dilip Patel, Adrianna Bielowka, Sindu Srikaran, Patricia Chaves Guerrero, Fatima S Govani, Inês G Mollet, Michela Noseda, Micheala A. Aldred, Claire L Shovlin
In order to identify cellular phenotypes resulting from nonsense (gain of stop/premature termination codon) variants, we devised a framework of analytic methods that minimised confounder contributions, and applied to blood outgrowth endothelial cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81cdff8980d68fa0ddb4a45f4b60f228
https://doi.org/10.1101/2021.12.05.471269
https://doi.org/10.1101/2021.12.05.471269
Autor:
Maria Paula Macedo, Inês G. Mollet
Distinct plasma microRNA profiles associate with different disease features. Elevated plasma microRNA hsa-miR-193b-3p has been reported in patients with pre-diabetes where early liver dysmetabolism plays a crucial role. MicroRNA target databases reve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1bc96045922fc03ca85c6614a324505
https://doi.org/10.1101/2021.01.22.427820
https://doi.org/10.1101/2021.01.22.427820
Autor:
Inês G. Mollet, Malin Fex, Lisa M. Nicholas, Bérengère Valtat, Nils Wierup, Lena Eliasson, Mia Abels, Deepak Jain, Hindrik Mulder, Lotta Andersson, Anya Medina
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 7, Pp 651-663 (2017)
Molecular Metabolism, Vol 6, Iss 7, Pp 651-663 (2017)
Objective Insulin release from pancreatic β-cells is controlled by plasma glucose levels via mitochondrial fuel metabolism. Therefore, insulin secretion is critically dependent on mitochondrial DNA (mtDNA) and the genes it encodes. Mitochondrial tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83dcd7ba5105a325832e60c6a31d48dc
https://doi.org/10.1016/j.molmet.2017.05.005
https://doi.org/10.1016/j.molmet.2017.05.005
Publikováno v:
Journal of Biological Chemistry. 291:18440-18452
Altered microRNA profiles have been demonstrated in experimental models of type 2 diabetes, including in islets of the diabetic Goto-Kakizaki (GK) rat. Our bioinformatic analysis of conserved sequences in promoters of microRNAs, previously observed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fb5026d755d560832b971657b5235d
https://doi.org/10.1074/jbc.m116.716860
https://doi.org/10.1074/jbc.m116.716860
Autor:
Anna Wendt, Thomas Reinbothe, Jones K. Ofori, Inês G. Mollet, Karin G. Stenkula, Jenny Vikman, Lena Eliasson, Helena Anna Malm, Jonathan L.S. Esguerra, Vishal A. Salunkhe
Publikováno v:
EBioMedicine, Vol 10, Iss C, Pp 185-194 (2016)
EBioMedicine
EBioMedicine
Statins are beneficial in the treatment of cardiovascular disease (CVD), but these lipid-lowering drugs are associated with increased incidence of new on-set diabetes. The cellular mechanisms behind the development of diabetes by statins are elusive.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a005eafcd177cf5b02d055efc09a2e
http://www.sciencedirect.com/science/article/pii/S2352396416303127
http://www.sciencedirect.com/science/article/pii/S2352396416303127