Výsledky vyhledávání - "Inês Direito"

Akademický článek

HumanEnerg Hotspot: Conceptual Design of an Agile Toolkit for Human Energy Reinforcement in Industry 5.0

Autor: Ifeoma Chukwunonso Onyemelukwe, José Antonio Vasconcelos Ferreira, Ana Luísa Ramos, Inês Direito

Publikováno v: Applied Sciences, Vol 14, Iss 18, p 8371 (2024)

This paper presents the conceptual design of the HumanEnerg Hotspot, an agile toolkit aimed at addressing the human energy crisis in the context of Industry 5.0. The toolkit has been developed using a blend of Design Science Research (DSR) and Human-

Externí odkaz: https://doaj.org/article/19e032cb710a4b2db6de2470e1e19449

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Akademický článek

The Clinicopathological Significance of BiP/GRP-78 in Breast Cancer: A Meta-Analysis of Public Datasets and Immunohistochemical Detection

Autor: Inês Direito, Daniela Gomes, Fátima Liliana Monteiro, Isa Carneiro, João Lobo, Rui Henrique, Carmen Jerónimo, Luisa Alejandra Helguero

Publikováno v: Current Oncology, Vol 29, Iss 12, Pp 9066-9087 (2022)

The endoplasmic reticulum chaperone BiP (also known as GRP-78 or HSPA5) maintains protein folding to allow cell proliferation and survival and has been implicated in carcinogenesis, tumor progression, and therapy resistance. BiP’s association with

Externí odkaz: https://doaj.org/article/db130825249a4125b5ceeba757a41084

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Akademický článek

Association Between Estrogen Receptors and GATA3 in Bladder Cancer: A Systematic Review and Meta-Analysis of Their Clinicopathological Significance

Autor: Carina Bernardo, Fátima L. Monteiro, Inês Direito, Francisco Amado, Vera Afreixo, Lúcio L. Santos, Luisa A. Helguero

Publikováno v: Frontiers in Endocrinology, Vol 12 (2021)

BackgroundEstrogen receptors alpha (ERα) and beta (ERβ) and the cooperating protein GATA-binding factor 3 (GATA3) have been implicated in bladder carcinogenesis and tumour progression. GATA3 and ER have been functionally linked in the establishment

Externí odkaz: https://doaj.org/article/1d9946fdd24a437c833bda0c152b4021

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Opportunities and barriers faced by early-career civil engineers enacting global responsibility

Autor: Inês Direito, Shannon M. Chance, John C. Mitchell

Publikováno v: Articles

The term ‘global responsibility’ projects a holistic sense of ethics, sustainability, and obligation. To achieve the long-term viability of human life on Earth, civil engineering must be conducted in increasingly responsible ways, and civil engin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb7fa1c10ba88ffbf588729c50f2761
https://doi.org/10.1080/03043797.2021.1990863

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Developing growth mindsets in engineering students: a systematic literature review of interventions

Autor: Anita Campbell, Mashudu Mokhithi, Inês Direito

Publikováno v: European Journal of Engineering Education. 46:503-527

Dropout from engineering studies has been linked to ‘fixed mindset’ beliefs of intelligence as fixed-at-birth that make students more likely to disengage when facing new challenges. In contrast, ‘g...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62a447ef4b97b274bce563065bfe86e2
https://doi.org/10.1080/03043797.2021.1903835

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Variation and phenomenography: recognising and understanding qualitatively different experiences of engineering learning

Autor: Mike Mimirinis, Shannon Chance, Inês Direito

Publikováno v: 9th Research in Engineering Education Symposium (REES 2021) and 32nd Australasian Association for Engineering Education Conference (REES AAEE 2021).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9fa4e668ae5c091af9fd54f069d2a9e6
https://doi.org/10.52202/066488-0149

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Protein Aggregation Patterns Inform about Breast Cancer Response to Antiestrogens and Reveal the RNA Ligase RTCB as Mediator of Acquired Tamoxifen Resistance

Autor: Rui Henrique, Luisa A. Helguero, Francisco Amado, Vera Enes, João Lobo, Inês Direito, Liliana Monteiro, Gabriela Moura, Tânia Melo, Margarida Fardilha, Manuel A. S. Santos, Daniela Figueira, Carmen Jerónimo

Publikováno v: Cancers, Vol 13, Iss 3195, p 3195 (2021)
Cancers
Volume 13
Issue 13

Simple Summary Acquired resistance to antiestrogenic therapy remains the major obstacle to curing luminal subtype breast cancer. While current treatment in acquired endocrine-resistant settings includes combined therapy with receptor tyrosine kinase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af644bd036d6fcd405c972d1f197e0f
https://www.mdpi.com/2072-6694/13/13/3195

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