Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Inês Cabrita"'
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Cl− channels such as the Ca2+ activated Cl− channel TMEM16A and the Cl− permeable phospholipid scramblase TMEM16F may affect the intracellular Cl− concentration ([Cl−]i), which could act as an intracellular signal. Loss of airway expression
Externí odkaz:
https://doaj.org/article/0e802036df2e47f9be703b08629185d7
Autor:
Karl Kunzelmann, Raquel Centeio, Podchanart Wanitchakool, Inês Cabrita, Roberta Benedetto, Tultul Saha, Kazi Mirajul Hoque, Rainer Schreiber
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Cl– secretion by the human and murine intestinal epithelium occurs through the cystic fibrosis transmembrane conductance regulator (cftr). However, the Ca2+ activated Cl– channel Tmem16a was shown to contribute to Cl– secretion, mainly, but not
Externí odkaz:
https://doaj.org/article/53df0f54cae54fc9ba59bfeea3e28ec3
Autor:
Karl Kunzelmann, Jiraporn Ousingsawat, Inês Cabrita, Tereza Doušová, Andrea Bähr, Melanie Janda, Rainer Schreiber, Roberta Benedetto
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The inflammatory airway disease cystic fibrosis (CF) is characterized by airway obstruction due to mucus hypersecretion, airway plugging, and bronchoconstriction. The cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel is dysf
Externí odkaz:
https://doaj.org/article/3f433d166663496689b1f4725e6e86dc
Autor:
Lioba Ester, Inês Cabrita, Michel Ventzke, Marita Christodoulou, Francesca Fabretti, Thomas Benzing, Sandra Habbig, Bernhard Schermer
BackgroundMutations in genes encoding nuclear pore proteins (NUPs) cause steroid-resistant nephrotic syndrome (SRNS) and focal and segmental glomerulosclerosis (FSGS). The mechanisms of how NUP deficiency may cause podocyte dysfunction and failure of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24c680373b1218855074bdd1cf40a474
https://doi.org/10.1101/2023.03.07.531564
https://doi.org/10.1101/2023.03.07.531564
Autor:
Rainer Schreiber, Joana R. Lérias, Jiraporn Ousingsawat, Raquel Centeio, Podchanart Wanitchakool, Karl Kunzelmann, Inês Cabrita, Roberta Benedetto
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 64:50-58
TMEM16A is a Ca2+-activated chloride channel that was shown to enhance production and secretion of mucus in inflamed airways. It is, however, not clear whether TMEM16A directly supports mucus produ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a9ca837494aa4b8e112a25bd218c51
https://doi.org/10.1165/rcmb.2019-0442oc
https://doi.org/10.1165/rcmb.2019-0442oc
Autor:
Raquel Centeio, Jiraporn Ousingsawat, Khaoula Talbi, Isaac Cohen, Rainer Schreiber, Kris De Boeck, Inês Cabrita, Tereza Doušová, Karl Kunzelmann, Roberta Benedetto, Eric Verbeken
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7852, p 7852 (2021)
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7852, p 7852 (2021)
Activation of the Ca2+ activated Cl- channel TMEM16A is proposed as a treatment in inflammatory airway disease. It is assumed that activation of TMEM16A will induce electrolyte secretion, and thus reduce airway mucus plugging and improve mucociliary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0c9f0520a9d82538f3086e8ceb43b9
https://epub.uni-regensburg.de/46060/
https://epub.uni-regensburg.de/46060/
Autor:
Rainer Schreiber, Madalena Pinto, Jiraporn Ousingsawat, Inês Cabrita, Joana R. Lérias, Podchanart Wanitchakool, Karl Kunzelmann, Roberta Benedetto
Publikováno v:
Journal of Molecular Medicine. 97:711-722
The cystic fibrosis transmembrane conductance regulator (CFTR) is the secretory chloride channel in epithelial tissues that has a central role in cystic fibrosis (CF) lung and gastrointestinal disease. A recent publication demonstrates a close associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68e6a867d6f44613a1341f9cae3335b
https://doi.org/10.1007/s00109-019-01770-4
https://doi.org/10.1007/s00109-019-01770-4
Publikováno v:
The FASEB Journal. 33:4502-4512
Transmembrane member 16A (TMEM16A) is the Ca2+-activated chloride channel in airways and intestine. It has been associated with goblet cell metaplasia, as expression of TMEM16A is strongly up-regulated in cystic fibrosis and asthma during mucus hyper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b2e16e61fe7a2b1b5b9bc5da0248ab
https://doi.org/10.1096/fj.201801333rrr
https://doi.org/10.1096/fj.201801333rrr
Autor:
Kathrin Skoczynski, Khaoula Talbi, Inês Cabrita, Rainer Schreiber, Karl Kunzelmann, Bjoern Buchholz, Sascha Hofmann, Andre Kraus
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of bilateral renal cysts which enlarge continuously, leading to compression of adjacent intact nephrons. The growing cysts lead to a progressive decline in renal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6240745b00ecfc89254d9d394d2764
Autor:
Botelho, Inês Cabrita
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
CIÊNCIAVITAE
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
CIÊNCIAVITAE
Mestrado em Contabilidade, Fiscalidade e Finanças Empresariais A presente dissertação tem como objetivo analisar em que medida o género dos gestores de topo, nomeadamente em cargos de presidente do conselho de administração, CEO e CFO, influenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8a16ce838b0548ad94c57672d8a63e19