Aldehyde Dehydrogenase 2 (ALDH2): A novel sorafenib target in hepatocellular carcinoma unraveled by the proteome-wide cellular thermal shift assay

Autor: Inês C. Ferreira, Estefania Torrejón, Bernardo Abecasis, Bruno M. Alexandre, Ricardo A. Gomes, Chris Verslype, Jos van Pelt, Ana Barbas, Daniel Simão, Tiago M. Bandeiras, Alessio Bortoluzzi, Sofia P. Rebelo

Publikováno v: SLAS Discovery, Vol 29, Iss 3, Pp 100154- (2024)

Sorafenib is a multikinase inhibitor indicated for first-line treatment of unresectable hepatocellular carcinoma. Despite its widespread use in the clinic, the existing knowledge of sorafenib mode-of-action remains incomplete. To build upon the curre

Externí odkaz: https://doaj.org/article/f74d704ab68c4276ae4077cfc067a125

Damage of Dental Amalgam and Resin-Matrix Composite Surfaces After Exposure to Bleaching Agents: An Integrative Review

Autor: Inês C. Ferreira, Júlio C.M. Souza, Bruno Henriques, Mutlu Özcan, Orlanda Torres, Paulo Rompante, Margarida Faria, Filipe Samuel Silva

Publikováno v: Journal of Bio- and Tribo-Corrosion. 7

The aim of this study was to perform an integrative systematic review on the damage of dental resin-matrix composite and amalgam surfaces after exposure to bleaching agents composed of hydrogen or urea (carbamide) peroxide. An electronic search on Pu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b9ba072869284e29b8acd0caf788985
https://doi.org/10.1007/s40735-021-00537-0

Arl13b Regulates Breast Cancer Cell Migration and Invasion by Controlling Integrin-Mediated Signaling

Autor: Pedro Castanheira, Inês C. Ferreira, Cristina Casalou, Andreia Ferreira, Alexandra Faustino, Ana Félix, José S. Ramalho, Daniela Vaqueirinho, Teresa Barona, Jacinta Serpa, Duarte C. Barral, Fernanda Silva

Publikováno v: Cancers, Vol 11, Iss 10, p 1461 (2019)
Cancers
Volume 11
Issue 10
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Breast cancer is the first cause of cancer-related mortality among women worldwide, according to the most recent estimates. This mortality is mainly caused by the tumors&rsquo
ability to form metastases. Cancer cell migration and invasion are es

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282abe3881eead9746ee43324d104961
https://www.mdpi.com/2072-6694/11/10/1461

Immature myeloid cells and tolerogenic cytokine profile in lung adenocarcinoma metastatic lymph nodes assessed by endobronchial ultrasound

Autor: Zélia Silva, Paula A. Videira, Glória Nunes, António Bugalho, Andreia S Mendes, Catarina Martins, Inês C. Ferreira

Publikováno v: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 37(1)

In lung cancer, the immune cell compartment of tumor-draining lymph nodes (TDLNs) dictate the response against tumors. This response is predominantly triggered by myeloid antigen-presenting cells (mAPCs) that capture antigens and, if matured, prime a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::748bfd2e7bccc75c6861af6d84744154
https://pubmed.ncbi.nlm.nih.gov/26264617

Operating Rule Optimization for Missouri River Reservoir System

Autor: Inês C. Ferreira, Jay R. Lund

Publikováno v: Journal of Water Resources Planning and Management. 122:287-295

This paper describes the application of deterministic optimization to the main stem Missouri River reservoir system and the development and testing of inferred optimal operating rules from these model results. An implicit stochastic optimization appr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e08300c455645e7ae6df223de1115f1
https://doi.org/10.1061/(asce)0733-9496(1996)122:4(287)