Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Inés Roger"'
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-18 (2024)
Abstract Background Epidermal remodeling and hypertrophy are hallmarks of skin fibrotic disorders, and keratinocyte to mesenchymal (EMT)-like transformations drive epidermis alteration in skin fibrosis such as keloids and hypertrophic scars (HTS). Wh
Externí odkaz:
https://doaj.org/article/1cda7b3f62df4e2ca60891c18b038721
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionExposure to solar radiation can cause a range of skin damage, including sunburn, erythema, skin carcinogenesis, the release of reactive oxygen species (ROS), inflammation, DNA damage, and photoaging. Other wavelengths beyond UVB, such as
Externí odkaz:
https://doaj.org/article/54c352b997ff42938d9e73a84541e4d3
Autor:
Javier Milara, Inés Roger, Paula Montero, Enrique Artigues, Juan Escrivá, Francisco Perez-Vizcaino, Julio Cortijo
Publikováno v:
Pharmacological Research, Vol 197, Iss , Pp 106985- (2023)
IL-11 is linked to fibrotic diseases, but its role in pulmonary hypertension is unclear. We examined IL-11's involvement in idiopathic pulmonary arterial hypertension (iPAH). Using samples from control (n = 20) and iPAH (n = 6) subjects, we assessed
Externí odkaz:
https://doaj.org/article/a2843b9e7dc14514a2a6e11d90c84fb7
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background Pulmonary hypertension (PH) associated to idiopathic pulmonary fibrosis (IPF) portends a poor prognosis. IL-11 has been implicated in fibrotic diseases, but their role on pulmonary vessels is unknown. Here we analyzed the contribu
Externí odkaz:
https://doaj.org/article/ffec8e50801e4d1dab02b3d58120d006
Publikováno v:
Heliyon, Vol 9, Iss 5, Pp e15613- (2023)
N-Acetyl-l-cysteine (NAC) acts as a precursor of the tripeptide glutathione (GSH), one of the principal cell mechanisms for reactive oxygen species (ROS) detoxification. Chronic obstructive pulmonary disease (COPD) is associated with enhanced inflamm
Externí odkaz:
https://doaj.org/article/b65af97470234b6ca00c5eece8f886df
Autor:
Inés Roger, Paula Montero, Antonio García, Javier Milara, Pilar Ribera, Jose Alejandro Pérez-Fidalgo, Julio Cortijo
Publikováno v:
Pharmaceuticals, Vol 15, Iss 9, p 1111 (2022)
Delayed-type hypersensitivity (DTH) is caused by a broad number of drugs used in clinic, and antineoplastic drugs show an elevated proportion of DTH, which potentially affects the quality of life of patients. Despite the serious problem and the negat
Externí odkaz:
https://doaj.org/article/d0f7d3f7d6034e73ad7644c7781034ae
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1423 (2022)
In the lungs, fibrosis is a growing clinical problem that results in shortness of breath and can end up in respiratory failure. Even though the main fibrotic disease affecting the lung is idiopathic pulmonary fibrosis (IPF), which affects the interst
Externí odkaz:
https://doaj.org/article/af3d76611b384bf5a4f02a5d4d31afe0
Autor:
Javier Milara, Lucía Díaz-Platas, Sonia Contreras, Pilar Ribera, Inés Roger, Beatriz Ballester, Paula Montero, Ángel Cogolludo, Esteban Morcillo, Julio Cortijo
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-18 (2018)
Abstract Background Lung inflammation in COPD is poorly controlled by inhaled corticosteroids (ICS). Strategies to improve ICS efficacy or the search of biomarkers who may select those patients candidates to receive ICS in COPD are needed. Recent dat
Externí odkaz:
https://doaj.org/article/4409b67e4f164f47b35d3c2f11bb9719
Autor:
Javier Milara, Gracia Hernandez, Beatriz Ballester, Anselm Morell, Inés Roger, P. Montero, Juan Escrivá, José M. Lloris, Maria Molina-Molina, Esteban Morcillo, Julio Cortijo
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is the most rapidly progressive and fatal fibrotic disorder, with no curative therapies. The signal transducer and activator of transcription 3 (STAT3) protein is activated in lung fibroblasts a
Externí odkaz:
https://doaj.org/article/a15d80acb2924a00a0345f0598c07b1b
Publikováno v:
Cells, Vol 10, Iss 12, p 3456 (2021)
Cellular senescence is the arrest of normal cell division and is commonly associated with aging. The interest in the role of cellular senescence in lung diseases derives from the observation of markers of senescence in chronic obstructive pulmonary d
Externí odkaz:
https://doaj.org/article/1ca78c95691943028031cbd308f2ce00