Breast cancer–secreted factors perturb murine bone growth in regions prone to metastasis

Autor: Mason N. Dean, Peter Fratzl, Wolfgang Wagermaier, Tengteng Tang, Chuang Liu, Inés Moreno-Jiménez, Claudia Fischbach, Aaron E. Chiou

Publikováno v: Science Advances

A correlative materials analysis approach reveals perturbed bone growth in a mouse model of premetastatic breast cancer.
Breast cancer frequently metastasizes to bone, causing osteolytic lesions. However, how factors secreted by primary tumors a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6689b5eecc5c48182a2be7f35b2b78
https://doi.org/10.1126/sciadv.abf2283

A humanised rat model of osteosarcoma reveals ultrastructural differences between bone and mineralised tumour tissue

Autor: Beat Schmutz, Jacqui A. McGovern, Marietta Landgraf, Boris Michael Holzapfel, Christoph A. Lahr, Onur Bas, Christoph Meinert, Tomoji Mashimo, Amaia Cipitria, Inés Moreno-Jiménez, Yoshiki Miyasaka, Dietmar W. Hutmacher, Ferdinand Wagner, Amanda Dos Santos Cavalcanti, Abbas Shafiee

Publikováno v: Bone. 158:116018

Current xenograft animal models fail to accurately replicate the complexity of human bone disease. To gain translatable and clinically valuable data from animal models, new in vivo models need to be developed that mimic pivotal aspects of human bone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88851e1de9d9fd4e98e5a6b9129c222
https://doi.org/10.1016/j.bone.2021.116018

^{The Chorioallantoic Membrane Assay for Biomaterial Testing in Tissue Engineering: A Short-TermIn VivoPreclinical Model}

Autor: Richard O.C. Oreffo, Janos M. Kanczler, Inés Moreno-Jiménez, Stefanie Inglis, Gry Hulsart-Billström

Publikováno v: Tissue Engineering Part C: Methods. 23:938-952

The fields of regenerative medicine and tissue engineering offer significant promise to address the urgent unmet need for therapeutic strategies in a number of debilitating conditions, diseases, and tissue needs of an aging population. Critically, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a626c157d96b9e1d985381950fdcdd
https://doi.org/10.1089/ten.tec.2017.0186

Correction: W.C. Mak, et al. Controlled Delivery of Human Cells by Temperature Responsive Microcapsules. J. Funct. Biomater. 2015, 6, 439–453

Autor: Wing Cheung Mak, Kim Olesen, May Griffith, Inés Moreno-Jiménez, Joel Edin, Mårten Skog, Petter Sivlér, Chyan-Jang Lee, David W. Courtman

Publikováno v: Journal of Functional Biomaterials
Journal of Functional Biomaterials, Vol 9, Iss 2, p 26 (2018)

Cell therapy is one of the most promising areas within regenerative medicine. However, its full potential is limited by the rapid loss of introduced therapeutic cells before their full effects can be exploited, due in part to anoikis, and in part to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9c717dc1113b13ee26dbefac5a388d
http://europepmc.org/articles/PMC6023367

Controlled Delivery of Human Cells by Temperature Responsive Microcapsules

Autor: Wing Cheung Mak, May Griffith, D. Courtman, Inés Moreno-Jiménez, K. Olesen, Petter Sivlér, Mårten Skog, Chyan-Jang Lee, Joel Edin

Publikováno v: Journal of Functional Biomaterials
Journal of Functional Biomaterials, Vol 6, Iss 2, Pp 439-453 (2015)
Volume 6
Issue 2
Pages 439-453

Cell therapy is one of the most promising areas within regenerative medicine. However, its full potential is limited by the rapid loss of introduced therapeutic cells before their full effects can be exploited, due in part to anoikis, and in part to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a60af149e61cdca6c78e17cecde1dce
http://europepmc.org/articles/PMC4493523