Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Inés Martin-Martin"'
Autor:
Il Hwan Kim, Julio César Castillo, Azadeh Aryan, Inés Martin-Martin, Marcela Nouzova, Fernando G Noriega, Ana Beatriz F Barletta, Eric Calvo, Zachary N Adelman, José M C Ribeiro, John F Andersen
Publikováno v:
PLoS Pathogens, Vol 16, Iss 1, p e1008288 (2020)
Insects rely on the innate immune system for defense against pathogens, some aspects of which are under hormonal control. Here we provide direct experimental evidence showing that the juvenile hormone-binding protein (mJHBP) of Aedes aegypti is requi
Externí odkaz:
https://doaj.org/article/fdfdbedddb8645bfb9b68a5acd84e301
Autor:
Zarna Rajeshkumar Pala, Thiago Luiz Alves e Silva, Mahnaz Minai, Benjamin Crews, Eduardo Patino-Martinez, Carmelo Carmona-Rivera, Paola Carolina Valenzuela Leon, Ines Martin-Martin, Yevel Flores-Garcia, Raul E. Cachau, Liya Muslinkina, Apostolos G. Gittis, Naman Srivastava, David N. Garboczi, Derron A. Alves, Mariana J. Kaplan, Elizabeth Fischer, Eric Calvo, Joel Vega-Rodriguez
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The evolution of hematophagy involves a series of adaptations that allow blood-feeding insects to access and consume blood efficiently while managing and circumventing the host’s hemostatic and immune responses. Mosquito, and other insects
Externí odkaz:
https://doaj.org/article/5f36b17f5200404f8da58a835144cc00
Autor:
Anna Fernández-Arévalo, Estela González, Cristina Ballart, Inés Martín-Martín, Silvia Tebar, Carme Muñoz, Maribel Jiménez, Ricardo Molina, Montserrat Gállego
Publikováno v:
Parasitology, Vol 151, Pp 213-219 (2024)
In 2009, a large outbreak of leishmaniasis, associated with environmental changes, was declared near Madrid (Spain), in which Phlebotomus perniciosus was the vector, whereas the main reservoirs were hares and rabbits. Analysis of isolates from humans
Externí odkaz:
https://doaj.org/article/e1818db3e83a45e181dddce587345250
Autor:
Vivian Petersen, Micael Santana, Maria Karina-Costa, Julia Jardim Nachbar, Ines Martin-Martin, Zach N. Adelman, Bianca C. Burini
Publikováno v:
Insects, Vol 15, Iss 8, p 600 (2024)
More than 3550 species of mosquitoes are known worldwide, and only a fraction is involved in the transmission of arboviruses. Mosquitoes in sylvatic and semi-sylvatic habitats may rapidly adapt to urban parks and metropolitan environments, increasing
Externí odkaz:
https://doaj.org/article/e2726cb7bf7e443ba4fe2134b465ae39
Autor:
Ines Martin-Martin, Bianca Burini Kojin, Azadeh Aryan, Adeline E. Williams, Alvaro Molina-Cruz, Paola Carolina Valenzuela-Leon, Gaurav Shrivastava, Karina Botello, Mahnaz Minai, Zach N. Adelman, Eric Calvo
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTMosquito saliva facilitates blood meal acquisition through pharmacologically active compounds that prevent host hemostasis and immune responses. Here, we generated two knockout (KO) mosquito lines by CRISPR/Cas9 to functionally characterize D
Externí odkaz:
https://doaj.org/article/3cccb39e9ce743b2811975d69e58eeef
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Introduction During evolution, blood-feeding arthropods developed a complex salivary mixture that can interfere with host haemostatic and immune response, favoring blood acquisition and pathogen transmission. Therefore, a survey of the saliv
Externí odkaz:
https://doaj.org/article/962abfc6d8d242219fe03e0892cad644
Autor:
Paola Carolina Valenzuela-Leon, Andrezza Campos Chagas, Ines Martin-Martin, Adeline E. Williams, Markus Berger, Gaurav Shrivastava, Andrew S. Paige, Michalis Kotsyfakis, Lucas Tirloni, Eric Calvo
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundSalivary glands from blood-feeding arthropods secrete several molecules that inhibit mammalian hemostasis and facilitate blood feeding and pathogen transmission. The salivary functions from Simulium guianense, the main vector of Onchocercia
Externí odkaz:
https://doaj.org/article/96fe3ccaab3c468c8977ff6b151f73a9
Autor:
Bianca B. Kojin, Ines Martin-Martin, Helena R. C. Araújo, Brian Bonilla, Alvaro Molina-Cruz, Eric Calvo, Margareth L. Capurro, Zach N. Adelman
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-15 (2021)
Abstract Background The invasion of the mosquito salivary glands by Plasmodium sporozoites is a critical step that defines the success of malaria transmission and a detailed understanding of the molecules responsible for salivary gland invasion could
Externí odkaz:
https://doaj.org/article/86f778f4fc9c4099a700856a80cd99ff
Autor:
Olivia Kern, Paola Carolina Valenzuela Leon, Apostolos G. Gittis, Brian Bonilla, Phillip Cruz, Andrezza Campos Chagas, Sundar Ganesan, Jose M.C. Ribeiro, David N. Garboczi, Ines Martin-Martin, Eric Calvo
Publikováno v:
Current Research in Structural Biology, Vol 3, Iss , Pp 95-105 (2021)
Female mosquitoes require blood meals for egg development. The saliva of blood feeding arthropods contains biochemically active molecules, whose anti-hemostatic and anti-inflammatory properties facilitate blood feeding on vertebrate hosts. While tran
Externí odkaz:
https://doaj.org/article/ebbe72364e61453cb6fb1c06a9f81770
Autor:
Ines Martin-Martin, Andrew Paige, Paola Carolina Valenzuela Leon, Apostolos G. Gittis, Olivia Kern, Brian Bonilla, Andrezza Campos Chagas, Sundar Ganesan, Leticia Barion Smith, David N. Garboczi, Eric Calvo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
D7 proteins are highly abundant in the salivary glands of several blood feeding insects. Here, the authors study the ligand binding specificity and physiological roles of the mosquito D7 proteins CxD7L1 and CxD7L2, showing that CxD7L1 acquired ADP-bi
Externí odkaz:
https://doaj.org/article/dada7b2dad22487ba29eabdf46abee8b