Towards Novel Biomimetic In Vitro Models of the Blood–Brain Barrier for Drug Permeability Evaluation

Autor: Inés Mármol, Sara Abizanda-Campo, Jose M. Ayuso, Ignacio Ochoa, Sara Oliván

Publikováno v: Bioengineering, Vol 10, Iss 5, p 572 (2023)

Current available animal and in vitro cell-based models for studying brain-related pathologies and drug evaluation face several limitations since they are unable to reproduce the unique architecture and physiology of the human blood–brain barrier.

Externí odkaz: https://doaj.org/article/a1ed7d703fc3495aa2bc6cb3b7c2d975

Biological Activity of NHC-Gold-Alkynyl Complexes Derived from 3-Hydroxyflavones

Autor: Inés Mármol, Javier Quero, Paula Azcárate, Elena Atrián-Blasco, Carla Ramos, Joana Santos, María Concepción Gimeno, María Jesús Rodríguez-Yoldi, Elena Cerrada

Publikováno v: Pharmaceutics, Vol 14, Iss 10, p 2064 (2022)

In this paper we describe the synthesis of new N-heterocyclic carbene (NHC) gold(I) derivatives with flavone-derived ligands with a propargyl ether group. The compounds were screened for their antimicrobial and anticancer activities, showing greater

Externí odkaz: https://doaj.org/article/47125ff9e95c4754b56f5e966a486c3f

Valorization of agro-food by-products and their potential therapeutic applications

Autor: Cristina M. R. Rocha, José A. Teixeira, María Jesús Rodríguez-Yoldi, Marta Pérez-Fernández, Pedro Ferreira-Santos, Raquel Ibarz, Olga Martín-Belloso, Jesús Osada, Javier Quero, Sandra García-Juiz, Inés Mármol

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Agro-food industries generate a huge amount of fruit and vegetable wastes. These residues are composed by structural parts (leaves, peels, pulps, seeds, roots and stems) after the extraction of their juices, and they are rich in bioactive compounds s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191831070dcddf7f7d8a11390d7dbbfb

Phenolic Composition, Antioxidant Capacity and Antiproliferative Activity of Ten Exotic Amazonian fruit

Autor: Jean-Louis Marty, Magda Márcia Becker, María Jesús Rodríguez-Yoldi, Sift Desk, Rupesh K. Mishra, Inés Mármol, Sergio Barbosa, Marty Jean Louis, Gaëlle Catanante, Gilvanda Silva Nunes, Oscar Núñez

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona

The socioeconomic, cultural, therapeutic, and nutritional potential of Amazonian fruits has been limited due to the scarce information about its phytochemical profile. The aim of this study was to determine the total phenolic content profiles by Foli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41b5e23fc4d676928fac8d50314b3fe
http://hdl.handle.net/2445/158540

A combination of Rosa canina extracts and gold complex favors apoptosis of Caco-2 cells by increasing oxidative stress and mitochondrial dysfunction

Autor: Jesús Osada, María Jesús Rodríguez-Yoldi, Carmen Ancín-Azpilicueta, Inés Mármol, Nerea Jiménez-Moreno, Elena Cerrada

Publikováno v: Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
instname
Academica-e: Repositorio Institucional de la Universidad Pública de Navarra
Universidad Pública de Navarra
Antioxidants, Vol 9, Iss 1, p 17 (2019)
Antioxidants
Volume 9
Issue 1
Zaguán. Repositorio Digital de la Universidad de Zaragoza

Given the alarming increase in colorectal cancer (CRC) worldwide, novel therapies are urgently needed. Plant-derived extracts have gained considerable interest in the last years due to their strong anticancer effect mediated by their unique bioactive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48eb137ffc97b5b976cbf00ca041e34
https://hdl.handle.net/2454/36863