Deficient thyroid hormone transport to the brain leads to impairments in axonal caliber and oligodendroglial development

Autor: Soledad Bárez-López, Daniela López-Espíndola, Marina Guillén-Yunta, Ana Guadaño-Ferraz, Víctor Valcárcel-Hernández, Inés López de Toledo Soler, A. García-Aldea

Publikováno v: Neurobiology of Disease, Vol 162, Iss, Pp 105567-(2022)
Valcárcel-Hernández, V, López-Espíndola, D, Guillén-Yunta, M, García-Aldea, Á, López de Toledo Soler, I, Bárez-López, S & Guadaño-Ferraz, A 2022, ' Deficient thyroid hormone transport to the brain leads to impairments in axonal caliber and oligodendroglial development ', Neurobiology of Disease, vol. 162, 105567, pp. 105567 . https://doi.org/10.1016/j.nbd.2021.105567

Mutations in the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) lead to profound brain alterations, including myelination impairments, in humans. We aimed to further explore the pathophysiological mechanisms underlying the MCT8 defi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0286027efd8230722231ccc0fef6a46
https://pubmed.ncbi.nlm.nih.gov/34838669