Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Inès Schmid"'
Autor:
Hans-Uwe Simon, Dagmar Simon, Leonardo Scapozza, Inès Schmid, Souzan Salemi, Shida Yousefi, L. Moretti
Publikováno v:
Allergy. 64:913-918
Background: The Fip1-like-1–platelet-derived growth factor receptor alpha (FIP1L1-PDGFRA) gene fusion is a common cause of chronic eosinophilic leukemia (CEL)/hypereosinophilic syndrome (HES), and patients suffering from this particular subgroup of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936d83915abd833a84d46fad3cb86035
https://doi.org/10.1111/j.1398-9995.2009.01943.x
https://doi.org/10.1111/j.1398-9995.2009.01943.x
Autor:
Hans-Uwe Simon, Jeffrey A. Gold, Alex Straumann, Nicola Andina, Shida Yousefi, Janine Reichenbach, Ann M. Kelly, Inès Schmid, Gerald J. Gleich, James J. Lee, Evelyne Kozlowski
Publikováno v:
Nature Medicine. 14:949-953
Although eosinophils are considered useful in defense mechanisms against parasites, their exact function in innate immunity remains unclear. The aim of this study is to better understand the role of eosinophils within the gastrointestinal immune syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd661d71289e73ef3d61f76e5dfea96c
https://doi.org/10.1038/nm.1855
https://doi.org/10.1038/nm.1855
Publikováno v:
Immunology Letters. 117:45-49
Bone marrow transplantation (BMT) is commonly used for the treatment of severe haematological and immunological diseases. For instance, the autoimmune lymphoproliferative syndrome (ALPS) caused by a complete expression defect of CD95 (Fas, APO-1) can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18d9211afb731bce58980c34d19ef9f
https://doi.org/10.1016/j.imlet.2007.11.019
https://doi.org/10.1016/j.imlet.2007.11.019
Autor:
Marc Messerschmidt, A.B. Soriaga, Roland Riek, Christian Riekel, Sébastien Boutet, M. Marvin Seibert, Garth J. Williams, Hans-Uwe Simon, Evelyne Kozlowski, Manfred Burghammer, Duilio Cascio, Christina Stoeckle, Alice Soragni, David Eisenberg, Jacques-Philippe Colletier, Nadia A. Zatsepin, Susanne Radonjic-Hoesli, Shida Yousefi, Inès Schmid, Michael R. Sawaya
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2015, 57 (6), pp.1011-21
Molecular Cell, 2015, 57 (6), pp.1011-21
Molecular cell, vol 57, iss 6
Molecular Cell, Elsevier, 2015, 57 (6), pp.1011-21
Molecular Cell, 2015, 57 (6), pp.1011-21
Molecular cell, vol 57, iss 6
International audience; Eosinophils are white blood cells that function in innate immunity and participate in the pathogenesis of various inflammatory and neoplastic disorders. Their secretory granules contain four cytotoxic proteins, including the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1dd3e0ff5f16c7633de0955a8dc83e
https://hal.univ-grenoble-alpes.fr/hal-01162651
https://hal.univ-grenoble-alpes.fr/hal-01162651
Publikováno v:
The Journal of Immunology. 174:8090-8096
Leptin regulates food intake as well as metabolic, endocrine, and immune functions. It exerts proliferative and antiapoptotic activities in a variety of cell types, including T cells. Leptin also stimulates macrophages and neutrophils, and its produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c20439148e5e22b9367a42b39c9336f
https://doi.org/10.4049/jimmunol.174.12.8090
https://doi.org/10.4049/jimmunol.174.12.8090
Autor:
Frank Altznauer, Hans-Uwe Simon, Inès Schmid, Peter Vogt, Shida Yousefi, Sibylla Martinelli, Christoph Mueller, Martin H. Schöni, Martin F. Fey, Uwe Zangemeister-Wittke, Christine Thürig, Edward M. Conway
Publikováno v:
The Journal of Experimental Medicine
Survivin has received great attention due to its expression in many human tumors and its potential as a therapeutic target in cancer. Survivin expression has been described to be cell cycle–dependent and restricted to the G2-M checkpoint, where it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3e630a7b1ce14430e9a4b496efb163
https://doi.org/10.1084/jem.20032033
https://doi.org/10.1084/jem.20032033
Autor:
Dipak Maskey, Robert R. Friis, Inès Schmid, Inti Zlobec, Aurel Perren, Hans-Uwe Simon, Shida Yousefi
Publikováno v:
Nature Communications
Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130
Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130
Anticancer drug therapy activates both molecular cell death and autophagy pathways. Here we show that even sublethal concentrations of DNA-damaging drugs, such as etoposide and cisplatin, induce the expression of autophagy-related protein 5 (ATG5), w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14215ebb44e6b219bbd9b7f96bff05ee
https://doi.org/10.1038/ncomms3130
https://doi.org/10.1038/ncomms3130
Publikováno v:
Cell Death and Differentiation
Cell death and differentiation
Cell death and differentiation
Neutrophil extracellular traps (NETs) represent extracellular structures able to bind and kill microorganisms. It is believed that they are generated by neutrophils undergoing cell death, allowing these dying or dead cells to kill microbes. We show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cec9245afcca640b3429c44debbd762
https://pubmed.ncbi.nlm.nih.gov/19609275
https://pubmed.ncbi.nlm.nih.gov/19609275
Autor:
Arezoo Daryadel, Carlo Mordasini, Inès Schmid, Hans-Uwe Simon, Andrew Ziemiecki, Clemens A. Dahinden, David Troi, Jan Schmidt-Mende, Shida Yousefi
Publikováno v:
Journal of immunology (Baltimore Md. : 1950)
Journal of Immunology
Journal of Immunology
Leukotriene B4 (LTB4) is an important proinflammatory lipid mediator generated by neutrophils upon activation. GM-CSF stimulation is known to enhance agonist-mediated LTB4 production of neutrophils within minutes, a process called “priming”. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6425ab2397967df998afd8d53852e0ef
https://pubmed.ncbi.nlm.nih.gov/19414807
https://pubmed.ncbi.nlm.nih.gov/19414807
Publikováno v:
Cell Death and Disease
Cell Death & Disease
Simon, Hans-Uwe; Yousefi, Shida; Schmid, Ines; Friis, Robert (2014). ATG5 can regulate p53 expression and activation. Cell death & disease, 5(e1339), pp. 176-177. Nature Publishing Group 10.1038/cddis.2014.308
Cell Death & Disease
Simon, Hans-Uwe; Yousefi, Shida; Schmid, Ines; Friis, Robert (2014). ATG5 can regulate p53 expression and activation. Cell death & disease, 5(e1339), pp. 176-177. Nature Publishing Group 10.1038/cddis.2014.308
Dear Editor, DNA-damaging anti-cancer drugs cause cell death by apoptosis, but they also activate macroautophagy1 (hereafter just autophagy), a fundamental survival pathway under stress where cells enclose cytosol or organelles in double-membrane aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371612f8d85726d865109e0d6e08521d
https://doi.org/10.1038/cddis.2014.308
https://doi.org/10.1038/cddis.2014.308