Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Inès Desanlis"'
Autor:
Viviane Tran, Sarah Nahlé, Amélie Robert, Inès Desanlis, Ryan Killoran, Sophie Ehresmann, Marie-Pier Thibault, David Barford, Kodi S. Ravichandran, Martin Sauvageau, Matthew J. Smith, Marie Kmita, Jean-François Côté
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Myoblast fusion is essential for development of multinucleated myofibers. Here, the authors show that ablation of Elmo 1 and Elmo2 impairs myoblast fusion in mice, and that expression of an open conformation of Elmo2 promotes muscle regeneration and
Externí odkaz:
https://doaj.org/article/a22ad2614bc34d80b49198ec4a0a5ec3
Autor:
Pauline Labbé, Victoria Munoz Goyette, Nathalie Thorin-Trescases, Louis Villeneuve, Ines Desanlis, Constance Delwarde, Yan-Fen Shi, Cécile Martel, Carol Yu, Azadeh Alikashani, Maya Mamarbachi, Frédéric Lesage, Samuel Mathieu, Jean-Claude Tardif, Patrick Mathieu, Marie Kmita, Éric Thorin
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-18 (2022)
Mice knockdown for Angiopoietin-like 2 (Angptl2) exhibit spontaneous aortic valve stenosis associated with a decrease in Notch signalling and an imbalance in cell apoptosis, senescence and proliferation during embryonic valve remodelling stage.
Externí odkaz:
https://doaj.org/article/d3d098d507604c479c8a3cf1d9dd3fe2
Autor:
Ines Desanlis, Yacine Kherdjemil, Alexandre Mayran, Yasser Bouklouch, Claudia Gentile, Rushikesh Sheth, Rolf Zeller, Jacques Drouin, Marie Kmita
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Pioneer factors direct cell fate through switching inaccessible chromatin to an accessible state at specific target enhancers. Here the authors show that HOX13 transcription factors have a pioneer activity which is required for the proper implementat
Externí odkaz:
https://doaj.org/article/f7f1aa4b6fd944ee94c69c85f704d178
Publikováno v:
Journal of Developmental Biology, Vol 8, Iss 4, p 31 (2020)
Limb patterning relies in large part on the function of the Hox family of developmental genes. While the differential expression of Hox genes shifts from the anterior–posterior (A–P) to the proximal–distal (P–D) axis around embryonic day 11 (
Externí odkaz:
https://doaj.org/article/2ede7bbd6d8a4abf8839df021b916b69