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Akademický článek

miRNAs in Heart Development and Disease.

Autor: Lozano-Velasco E; Cardiovascular Development Group, Department of Experimental Biology, University of Jaen, 23071 Jaen, Spain., Inácio JM; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1150-082 Lisbon, Portugal., Sousa I; Genome Medicine Lab, Department of Medical Sciences, Institute for Biomedicine-iBiMED, University of Aveiro, 3810-193 Aveiro, Portugal., Guimarães AR; Genome Medicine Lab, Department of Medical Sciences, Institute for Biomedicine-iBiMED, University of Aveiro, 3810-193 Aveiro, Portugal., Franco D; Cardiovascular Development Group, Department of Experimental Biology, University of Jaen, 23071 Jaen, Spain., Moura G; Genome Medicine Lab, Department of Medical Sciences, Institute for Biomedicine-iBiMED, University of Aveiro, 3810-193 Aveiro, Portugal., Belo JA; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1150-082 Lisbon, Portugal.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 30; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 30.

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Akademický článek

Myocardial RNA Sequencing Reveals New Potential Therapeutic Targets in Heart Failure with Preserved Ejection Fraction.

Autor: Inácio JM; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal., Cristo F; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal., Pinheiro M; Genome Medicine Lab, Department of Medical Sciences, Institute for Biomedicine-iBiMED, University of Aveiro, 3810-193 Aveiro, Portugal., Vasques-Nóvoa F; Cardiovascular R&D Centre-UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, 1169-056 Porto, Portugal., Saraiva F; Cardiovascular R&D Centre-UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, 1169-056 Porto, Portugal., Nunes MM; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal., Rosas G; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal., Reis A; Genome Medicine Lab, Department of Medical Sciences, Institute for Biomedicine-iBiMED, University of Aveiro, 3810-193 Aveiro, Portugal., Coimbra R; Genome Medicine Lab, Department of Medical Sciences, Institute for Biomedicine-iBiMED, University of Aveiro, 3810-193 Aveiro, Portugal., Oliveira JL; Institute of Electronics and Informatics Engineering of Aveiro (IEETA), University of Aveiro, 3810-193 Aveiro, Portugal., Moura G; Genome Medicine Lab, Department of Medical Sciences, Institute for Biomedicine-iBiMED, University of Aveiro, 3810-193 Aveiro, Portugal., Leite-Moreira A; Cardiovascular R&D Centre-UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, 1169-056 Porto, Portugal., Belo JA; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School|Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal.

Publikováno v: Biomedicines [Biomedicines] 2023 Jul 28; Vol. 11 (8). Date of Electronic Publication: 2023 Jul 28.

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Akademický článek

Depletion of DAND5 Hinders EMT in Mouse Embryonic Stem Cell Differentiation.

Autor: von Gilsa Lopes J; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical Schoo.; Faculdade de Ciências Médicas, NM.; FCM, Universidade Nova de Lisboa; Lisboa, Portugal., Inácio JM; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical Schoo.; Faculdade de Ciências Médicas, NM.; FCM, Universidade Nova de Lisboa; Lisboa, Portugal., Marques S; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical Schoo.; Faculdade de Ciências Médicas, NM.; FCM, Universidade Nova de Lisboa; Lisboa, Portugal., Añez SB; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical Schoo.; Faculdade de Ciências Médicas, NM.; FCM, Universidade Nova de Lisboa; Lisboa, Portugal., Belo JA; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical Schoo.; Faculdade de Ciências Médicas, NM.; FCM, Universidade Nova de Lisboa; Lisboa, Portugal.

Publikováno v: Current stem cell research & therapy [Curr Stem Cell Res Ther] 2023 May 16. Date of Electronic Publication: 2023 May 16.

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Akademický článek

Gene-Edited Human-Induced Pluripotent Stem Cell Lines to Elucidate DAND5 Function throughout Cardiac Differentiation.

Autor: Inácio JM; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School/Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1150-082 Lisboa, Portugal., Nunes MM; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School/Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1150-082 Lisboa, Portugal., Almeida M; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School/Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1150-082 Lisboa, Portugal., Cristo F; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School/Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1150-082 Lisboa, Portugal., Anjos R; Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, 1449-005 Lisboa, Portugal., Belo JA; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School/Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1150-082 Lisboa, Portugal.

Publikováno v: Cells [Cells] 2023 Feb 05; Vol. 12 (4). Date of Electronic Publication: 2023 Feb 05.

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Akademický článek

A novel biallelic loss-of-function variant in DAND5 causes heterotaxy syndrome.

Autor: Ganapathi M; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York 10032, USA., Buchovecky CM; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York 10032, USA., Cristo F; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1099-085 Lisboa, Portugal., Ahimaz P; Department of Pediatrics, Columbia University Irving Medical Center, New York, New York 10032, USA., Ruzal-Shapiro C; Department of Radiology, Columbia University Irving Medical Center, New York, New York 10032, USA., Wou K; Department of Pediatrics, Columbia University Irving Medical Center, New York, New York 10032, USA., Inácio JM; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1099-085 Lisboa, Portugal., Iglesias A; Department of Pediatrics, Columbia University Irving Medical Center, New York, New York 10032, USA., Belo JA; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1099-085 Lisboa, Portugal., Jobanputra V; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York 10032, USA.

Publikováno v: Cold Spring Harbor molecular case studies [Cold Spring Harb Mol Case Stud] 2022 Dec 28; Vol. 8 (7). Date of Electronic Publication: 2022 Dec 28 (Print Publication: 2022).

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Akademický článek

CCBE1 Is Essential for Epicardial Function during Myocardium Development.

Autor: Bonet F; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School/Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal.; Medicine Department, School of Medicine, University of Cádiz (UCA), 11003 Cádiz, Spain., Añez SB; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School/Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal., Inácio JM; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School/Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal., Futschik ME; MRC London Institute of Medical Sciences (LMS), Faculty of Medicine, Hammersmith Hospital Campus, Imperial College London, Du Cane Road, London W12 0NN, UK., Belo JA; Stem Cells and Development Laboratory, iNOVA4Health, NOVA Medical School/Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Oct 20; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 20.

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Akademický článek

CCBE1 in Cardiac Development and Disease.

Autor: Bonet F; Stem Cells and Development Laboratory, CEDOC, Chronic Diseases Research Centre, NOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal.; Medicine Department, School of Medicine, University of Cádiz (UCA), Cádiz, Spain.; Research Unit, Biomedical Research and Innovation Institute of Cadiz (INiBICA), Puerta del Mar University Hospital, Cádiz, Spain., Inácio JM; Stem Cells and Development Laboratory, CEDOC, Chronic Diseases Research Centre, NOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal., Bover O; Stem Cells and Development Laboratory, CEDOC, Chronic Diseases Research Centre, NOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal., Añez SB; Stem Cells and Development Laboratory, CEDOC, Chronic Diseases Research Centre, NOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal., Belo JA; Stem Cells and Development Laboratory, CEDOC, Chronic Diseases Research Centre, NOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal.

Publikováno v: Frontiers in genetics [Front Genet] 2022 Feb 09; Vol. 13, pp. 836694. Date of Electronic Publication: 2022 Feb 09 (Print Publication: 2022).

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Akademický článek

DAND5 Inactivation Enhances Cardiac Differentiation in Mouse Embryonic Stem Cells.

Autor: Inácio JM; iNOVA4Health, CEDOC, NOVA Medical School, NMS, Universidade Nova de Lisboa, Lisbon, Portugal., von Gilsa Lopes J; iNOVA4Health, CEDOC, NOVA Medical School, NMS, Universidade Nova de Lisboa, Lisbon, Portugal., Silva AM; iNOVA4Health, CEDOC, NOVA Medical School, NMS, Universidade Nova de Lisboa, Lisbon, Portugal., Cristo F; iNOVA4Health, CEDOC, NOVA Medical School, NMS, Universidade Nova de Lisboa, Lisbon, Portugal., Marques S; iNOVA4Health, CEDOC, NOVA Medical School, NMS, Universidade Nova de Lisboa, Lisbon, Portugal., Futschik ME; Faculty of Medicine, School of Public Health, Imperial College London, Medical School, St. Mary's Hospital, London, United Kingdom., Belo JA; iNOVA4Health, CEDOC, NOVA Medical School, NMS, Universidade Nova de Lisboa, Lisbon, Portugal.

Publikováno v: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2021 Apr 13; Vol. 9, pp. 629430. Date of Electronic Publication: 2021 Apr 13 (Print Publication: 2021).

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