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of 210
pro vyhledávání: '"Imrie, H."'
Autor:
Sengupta, A, Patel, PA, Yuldasheva, NY, Mughal, RS, Galloway, S, Viswambharan, H, Walker, AMN, Aziz, A, Smith, J, Ali, N, Mercer, BN, Imrie, H, Sukumar, P, Wheatcroft, SB, Kearney, MT, Cubbon, RM
Publikováno v:
Endocrinology
Reduced systemic insulin signaling promotes endothelial dysfunction and diminished endogenous vascular repair. We investigated whether restoration of endothelial insulin receptor expression could rescue this phenotype. Insulin receptor knockout (IRKO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e95a99911c19bb34dc33a42b829d69b0
http://europepmc.org/articles/PMC6047419
http://europepmc.org/articles/PMC6047419
Autor:
Imrie, H, Williams, DJL
Background: Bacterial lipopolysaccharide and interferon-γ stimulation of rodent macrophages in vitro induces up-regulation of inducible nitric oxide synthase, whereas interleukin-4 stimulation results in increased activity of arginase-1. Thus differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::c27d32cacbb6fb651e9a20531c44a229
https://irep.ntu.ac.uk/id/eprint/36180/1/13700_Imrie.pdf
https://irep.ntu.ac.uk/id/eprint/36180/1/13700_Imrie.pdf
Autor:
Watt, N T, Gage, M C, Patel, P A, Viswambharan, H, Sukumar, P, Galloway, S, Yuldasheva, N Y, Imrie, H, Walker, A M N, Griffin, K J, Makava, N, Skromna, A, Bridge, K, Beech, D J, Schurmans, S, Wheatcroft, S B, Kearney, M T, Cubbon, R M
Publikováno v:
DIABETES
Shc homology 2–containing inositol 5′ phosphatase-2 (SHIP2) is a lipid phosphatase that inhibits insulin signaling downstream of phosphatidylinositol 3-kinase (PI3K); its role in vascular function is poorly understood. To examine its role in endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::b61f3e9cf3da9e725d42d3d3f70fa699
Autor:
Freel, M, Keavney, B, Avery, P, Mayosi, B, Gaukrodger, N, Imrie, H, Baker, M, Fraser, R, Ingram, M, Watkins, H, Farrall, M, Davies, E, Connell, J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::113f6675fc5b30eaafd66f6d36fe1c64
https://ora.ox.ac.uk/objects/uuid:6d17088a-56d2-4c18-adce-db20303fc6eb
https://ora.ox.ac.uk/objects/uuid:6d17088a-56d2-4c18-adce-db20303fc6eb
NOX2 NADPH-OXIDASE A NOVEL TARGET TO PREVENT INSULIN RESISTANCE RELATED ENDOTHELIAL CELL DYSFUNCTION
Autor:
Sukumar, P, Viswambharan, H, Imrie, H, Cubbon, RM, Yuldasheva, N, Gage, M, Galloway, S, Skromna, A, Smith, J, Gatenby, K, Beech, DJ, Wheatcroft, SB, Channon, KM, Shah, AM, Kearney, MT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d620317bf8277259e25d7057ca679122
https://doi.org/10.1136/heartjnl-2012-301877b.105
https://doi.org/10.1136/heartjnl-2012-301877b.105
Autor:
Sukumar, P, Viswambharan, H, Imrie, H, Cubbon, R, Yuldasheva, N, Gage, M, Galloway, S, Skromna, A, Kandavelu, P, Santos, C, Gatenby, K, Smith, J, Beech, D, Wheatcroft, S, Channon, K, Shah, A, Kearney, M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b126bd02c8774568159b8ec0296f7d5c
https://doi.org/10.1136/heartjnl-2013-304019.278
https://doi.org/10.1136/heartjnl-2013-304019.278
Akademický článek
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Autor:
Imrie, H. J.1, Jones, D. R. E.1
Publikováno v:
Clinical & Experimental Immunology. Jul1997, Vol. 109 Issue 1, p217-222. 6p.
Autor:
Li, J, Hou, B, Tumova, S, Muraki, K, Bruns, A, Ludlow, MJ, Sedo, A, Hyman, AJ, McKeown, L, Young, RS, Yuldasheva, NY, Majeed, Y, Wilson, LA, Rode, B, Bailey, MA, Kim, HR, Fu, Z, Carter, DAL, Bilton, J, Imrie, H, Ajuh, P, Dear, TN, Cubbon, RM, Kearney, MT, Prasad, KR, Evans, PC, Ainscough, JFX, Beech, DJ
The mechanisms by which physical forces regulate endothelial cells to determine the complexities of vascular structure and function are enigmatic1, 2, 3, 4, 5. Studies of sensory neurons have suggested Piezo proteins as subunits of Ca2+-permeable non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::90ca06d946391d0337daeb429c76b1b9
Autor:
Imrie, H, Viswambharan, H, Sukumar, P, Abbas, A, Cubbon, RM, Yuldasheva, N, Gage, M, Smith, J, Galloway, S, Skromna, A, Rashid, ST, Futers, TS, Xuan, S, Gatenby, VK, Grant, PJ, Channon, KM, Beech, DJ, Wheatcroft, SB, Kearney, MT
Publikováno v:
Diabetes. 61(9)
We recently demonstrated that reducing IGF-1 receptor (IGF-1R) numbers in the endothelium enhances nitric oxide (NO) bioavailability and endothelial cell insulin sensitivity. In the present report, we aimed to examine the effect of increasing IGF-1R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::28e8d93af410d48a6b206ec118d37f82
http://ora.ox.ac.uk/objects/uuid:396eae77-dd2b-4b0a-b59d-95d6b2095146
http://ora.ox.ac.uk/objects/uuid:396eae77-dd2b-4b0a-b59d-95d6b2095146