Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Imre Markovits"'
Autor:
Hajnalka Pataki, Imre Markovits, Kornélia Tacsi, István Csontos, Zsombor Kristóf Nagy, György Marosi, Ferenc Farkas, Brigitta Nagy, András Domokos
Publikováno v:
Crystal Growth & Design. 20:4433-4442
Crystallization as the most widespread purification, separation, and morphology-determining method is a critical technology that could be made safer and more economical by using continuous crystall...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c00ae0330c1db0857fb5c9d80a2a0ade
https://doi.org/10.1021/acs.cgd.0c00252
https://doi.org/10.1021/acs.cgd.0c00252
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 135:3043-3055
Bisoprolol fumarate is a beta blocker-type drug substance which has been well known for several decades. However, no relevant data can be found in the literature about its crystal polymorphism. The purpose of this paper was to present two anhydrous f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0b3d9d50c4773ba36279cdbbadc6513
https://doi.org/10.1007/s10973-018-7553-8
https://doi.org/10.1007/s10973-018-7553-8
Publikováno v:
Crystal Growth & Design. 12:5621-5628
Real-time Raman spectroscopy was used to characterize the solvent-mediated polymorphic transition and cooling crystallization of carvedilol. Kinetically preferred Form II was transformed into therm...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62bb1a465c5cb3773faa9added63d832
https://doi.org/10.1021/cg301135z
https://doi.org/10.1021/cg301135z
Publikováno v:
Chemical Engineering & Technology. 33:845-850
The optimization of filling up crystallization of a specific active pharmaceutical ingredient (APIe) is presented and discussed. Filling up crystallization is a special cooling crystallization method the main goal of which is to narrow the crystal si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::443499eb377d818b95c24578c8577767
https://doi.org/10.1002/ceat.200900579
https://doi.org/10.1002/ceat.200900579
Autor:
Katalin Marthi, Elemér Fogassy, Mátyás Czugler, Gabriella Egri, József Bálint, Krisztina Temesvári-Takács, Ádám Demeter, Imre Markovits
Publikováno v:
Tetrahedron: Asymmetry. 12:3417-3422
1-(4′-Carboxyphenyl)-2-methyl-3-(piperidine-1-yl)-propan-1-one M3 , erythro -1-(4′-carboxyphenyl)-2-methyl-3-(piperidine-1-yl)-propan-1-ol M4 and threo -1-(4′-carboxyphenyl)-2-methyl-3-(piperidine-1-yl)-propan-1-ol M5 , metabolites of the muscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55cb62753cfc536a72182c1b41df63c3
https://doi.org/10.1016/s0957-4166(02)00025-3
https://doi.org/10.1016/s0957-4166(02)00025-3
Autor:
László Párkányi, Zsuzsanna Tuza, Gabriella Egri, Elemér Fogassy, Imre Markovits, József Bálint
Publikováno v:
Tetrahedron: Asymmetry. 12:719-724
1-(4′-Hydroxymethyl-phenyl)-2-methyl-3-(piperidine-1-yl)-propane-1-one M2, a metabolite of tolperisone, was synthesised in a solvent-free Mannich reaction. The optical resolution was carried out by diastereoisomeric salt formation and separation, f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebae1093d779d9ae53ea0fddd6466cc6
https://doi.org/10.1016/s0957-4166(01)00088-x
https://doi.org/10.1016/s0957-4166(01)00088-x
Publikováno v:
Tetrahedron: Asymmetry. 11:1323-1329
The synthesis and resolution of a Tolperisone metabolite ((3′-hydroxy-4′-methylphenyl)-2-methyl-3-(piperidine-1-yl)-1-propane-1-one, M1 ) is described. Racemic M1 was subjected to resolution by the enantiomers of camphor-10-sulfonic acid. Absolut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8e6af0b9001810792af609c3f04974b
https://doi.org/10.1016/s0957-4166(00)00047-1
https://doi.org/10.1016/s0957-4166(00)00047-1
Publikováno v:
Chirality. 14:674-676
During an optical resolution it is the resolving agent that has the strongest influence on the outcome of the process. Applying a mixture of resolving agents can result either in antagonism or in synergy. We found that using mixtures of tartaric acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959c9836630e8e4632d40ecdf063f960
https://doi.org/10.1002/chir.10122
https://doi.org/10.1002/chir.10122
Autor:
A. Mravik, G. Pokol, Dóra K. Menyhárd, E. Fogassy, Imre Markovits, Z. Boecskei, Zoltán Katona
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::889f013e5539ddac5891b7b1576336b8
https://doi.org/10.1002/chin.199648043
https://doi.org/10.1002/chin.199648043
Autor:
Tibor Chován, Imre Markovits, Lajos Nagy, Ferenc Szeifert, Béla Farkas, Károly Nyı́ri, Kalman Nagy
Application of automated laboratory reactor systems and suitable model-based approaches can speed up significantly the process development of active pharmaceutical ingredients. The paper presents the design and functions of such a reactor system incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41ec6901e8268fb07206434e668fcad0
https://doi.org/10.1016/s1570-7946(06)80191-4
https://doi.org/10.1016/s1570-7946(06)80191-4
