Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Imre Kovesdi"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/7eaf6cae25c240b5b44c224b0aee7cce
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 226 (2023)
Practically the entire global population is infected by herpesviruses that establish lifelong latency and can be reactivated. Alpha-herpesviruses, herpes simplex viruses 1 and 2 (HSV-1/HSV-2) and varicella zoster virus (VZV), establish latency in sen
Externí odkaz:
https://doaj.org/article/4ac4f9e8ae654d7f8c5e6821954bc7fd
Autor:
Imre Kovesdi, Susan J. Hedley
Publikováno v:
Viruses, Vol 2, Iss 8, Pp 1681-1703 (2010)
Adenovirus (Ad) vectors, in particular those of the serotype 5, are highly attractive for a wide range of gene therapy, vaccine and virotherapy applications (as discussed in further detail in this issue). Wild type Ad5 virus can replicate in numerous
Externí odkaz:
https://doaj.org/article/6882479fe23a47c8a182b5ee7fdd2d6a
Dendritic cell based PSMA immunotherapy for prostate cancer using a CD40-targeted adenovirus vector.
Autor:
Briana Jill Williams, Shilpa Bhatia, Lisa K Adams, Susan Boling, Jennifer L Carroll, Xiao-Lin Li, Donna L Rogers, Nikolay Korokhov, Imre Kovesdi, Alexander V Pereboev, David T Curiel, J Michael Mathis
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46981 (2012)
Human prostate tumor vaccine and gene therapy trials using ex vivo methods to prime dendritic cells (DCs) with prostate specific membrane antigen (PSMA) have been somewhat successful, but to date the lengthy ex vivo manipulation of DCs has limited th
Externí odkaz:
https://doaj.org/article/d4079c23b3194e1690485a4b99d91cdd
Autor:
J Michael Mathis, Shilpa Bhatia, Alok Khandelwal, Imre Kovesdi, Stephen J Lokitz, Yoshi Odaka, Amol M Takalkar, Tracee Terry, David T Curiel
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16792 (2011)
As the limits of existing treatments for cancer are recognized, clearly novel therapies must be considered for successful treatment; cancer therapy using adenovirus vectors is a promising strategy. However tracking the biodistribution of adenovirus v
Externí odkaz:
https://doaj.org/article/fd956121b25045b39bff5448a98c0b40
Autor:
Judith Mühlhauser, Antonella Mangoni, Dieter Marmé, Donald P. Bottaro, Petra Reusch, Young H. Lee, Maurizio C. Capogrossi, Imre Kovesdi, Dinuka M. De Silva, Angelina Felici
Publikováno v:
Cancers; Volume 14; Issue 24; Pages: 6175
Two vascular endothelial growth factor (VEGF) receptors, FLT-1 and KDR, are expressed preferentially in proliferating endothelium. There is increasing evidence that recombinant, soluble VEGF receptor domains interfering with VEGF signaling may inhibi
Autor:
Angelina, Felici, Donald P, Bottaro, Antonella, Mangoni, Petra, Reusch, Dieter, Marmé, Imre, Kovesdi, Dinuka M, De Silva, Young H, Lee, Maurizio C, Capogrossi, Judith, Mühlhauser
Publikováno v:
Cancers. 14(24)
Two vascular endothelial growth factor (VEGF) receptors, FLT-1 and KDR, are expressed preferentially in proliferating endothelium. There is increasing evidence that recombinant, soluble VEGF receptor domains interfering with VEGF signaling may inhibi
Publikováno v:
Cureus.
Background Coronavirus disease 2019 (COVID-19) vaccination has substantially altered the course of the pandemic, saving tens of millions of lives globally. The problem is that despite such spectacular results, vaccination alone will not be able to co
Publikováno v:
Cureus. 14(3)
Based on the recommendation of the International Coalition to Eliminate hepatitis B virus (ICE-HBV), we intend to mimic the spontaneous resolution of HBV infection to achieve a functional cure of chronic hepatitis B virus (HBV) infection. To this end
Autor:
Tibor Bakacs, Volker Sandig, Shimon Slavin, Serhat Gumrukcu, David Hardy, Wolfgang Renz, Imre Kovesdi
Publikováno v:
Infectious disorders drug targets.
Abstract: More than 200 viruses infect humans, but treatments are available for less than ten of them. To narrow the gap between ‘bugs and drugs,’ a paradigm shift is required. The “one drug, one bug” approach can be expanded to a “one drug