Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Imre Derényi"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Almost all cancer types share the hallmarks of cancer and a similar tumor formation: fueled by stochastic mutations in somatic cells. In case of chronic myeloid leukemia (CML), this evolutionary process can be tracked from an asymptomatic lo
Externí odkaz:
https://doaj.org/article/d67604715b774684ba9021ee7f8e3122
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
The observation that tissues that undergo more stem cell divisions are less prone to develop cancer presents a paradox as these tissues should have more opportunity to accumulate cancer-causing mutations. Here, the authors present a solution to the p
Externí odkaz:
https://doaj.org/article/2c3be501fe9e43b4b6cbd6229b43d893
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 4, p e1010048 (2022)
Tumors often harbor orders of magnitude more mutations than healthy tissues. The increased number of mutations may be due to an elevated mutation rate or frequent cell death and correspondingly rapid cell turnover, or a combination of the two. It is
Externí odkaz:
https://doaj.org/article/336401b7b3fd457abc75277995ed663c
Publikováno v:
Applied Network Science, Vol 4, Iss 1, Pp 1-13 (2019)
Abstract Humans predominantly form their beliefs based on communication with other humans rather than direct observations, even on matters of facts, such as the shape of the globe or the effects of child vaccinations. Despite the fact that this is a
Externí odkaz:
https://doaj.org/article/a940ef73ca8947b48b925c6c783af176
Autor:
Tamás Gerecsei, Rita Ungai-Salánki, András Saftics, Imre Derényi, Robert Horvath, Bálint Szabó
Publikováno v:
Colloids and Interfaces, Vol 6, Iss 1, p 14 (2022)
Water in oil emulsions have a wide range of applications from chemical technology to microfluidics, where the stability of water droplets is of paramount importance. Here, using an accessible and easily reproducible experimental setup we describe and
Externí odkaz:
https://doaj.org/article/a7d3cd67458740e793095904500b5431
Autor:
Imre Derényi, Gergely J. Szöllősi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
To limit the accumulation of somatic mutations, renewing tissues must minimize the number of times each cell divides during differentiation. Here, the authors analytically derive the lower limit of lifetime divisional load of a tissue, show that hier
Externí odkaz:
https://doaj.org/article/a73bfd5d10674b91ad5f4d27c0ecfe16
Publikováno v:
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Renewed tissues of multicellular organism accumulate mutations that lead to aging and cancer. To mitigate these effects, self-renewing tissues produce cells along differentiation hierarchies, which have been shown to suppress somatic evo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b300561c58ccbb48f3d634fa012db673
https://doi.org/10.1073/pnas.1913104117
https://doi.org/10.1073/pnas.1913104117
Publikováno v:
NAT COMMUN NATURE COMMUNICATIONS.
Species-specific differences control cancer risk across orders of magnitude variation in body size and lifespan, e.g., by varying the copy numbers of tumor suppressor genes. It is unclear, however, how different tissues within an organism can control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd64c950fccc558ae6d389f4ddd6129a
http://hdl.handle.net/10831/89605
http://hdl.handle.net/10831/89605
Autor:
Beatrix Peter, Sándor Kurunczi, Bálint Szabó, Robert Horvath, Imre Derényi, Csaba Hős, Tamás Gerecsei, István Erdődi
Publikováno v:
Journal of Colloid and Interface Science. 555:245-253
Characterization of the binding of functionalized microparticles to surfaces with a specific chemistry sheds light on molecular scale interactions. Polymer or protein adsorption are often monitored by colloid particle deposition. Force measurements o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f5d6c7afff53439d5efd5abbf8a095
https://doi.org/10.1016/j.jcis.2019.07.102
https://doi.org/10.1016/j.jcis.2019.07.102
A remarkable property of plants is their ability to accumulate mutations at a very slow pace despite their potentially long lifespans, during which they continually form buds, each with the potential to become a new branch. Because replication errors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d109717df93c0b062662042d44cd692
https://doi.org/10.1101/2021.02.13.431063
https://doi.org/10.1101/2021.02.13.431063
