Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Imre, Kacskovics"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Members of the NOX/DUOX family of NADPH oxidases are responsible for regulated ROS production in diverse cells and tissues. Detection of NOX/DUOX proteins at the protein level remains an important challenge in the field. Here we report the d
Externí odkaz:
https://doaj.org/article/0b71a7cb6b8a49a19949a189a0b71dc8
Autor:
Anita Marx, Magdolna Osváth, Bence Szikora, Orsolya Pipek, István Csabai, Ákos Nagy, Csaba Bödör, Zsolt Matula, Ginette Nagy, András Bors, Ferenc Uher, Gábor Mikala, István Vályi-Nagy, Imre Kacskovics
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285696 (2023)
The need for sensitive monitoring of minimal/measurable residual disease (MRD) in multiple myeloma emerged as novel therapies led to deeper responses. Moreover, the potential benefits of blood-based analyses, the so-called liquid biopsy is prompting
Externí odkaz:
https://doaj.org/article/72c26859dca34bd784adcddfb998a56a
Autor:
Veronika F.S. Pape, Hajnal A. Kovács, István Szatmári, Imre Ugrai, Bence Szikora, Imre Kacskovics, Zoltán May, Norbert Szoboszlai, Gábor Sirokmány, Miklós Geiszt
Publikováno v:
Redox Biology, Vol 54, Iss , Pp 102385- (2022)
Peroxidasin (PXDN) is involved in the crosslinking of collagen IV, a major constituent of basement membranes. Disruption of basement membrane integrity as observed in genetic alterations of collagen IV or PXDN can result in developmental defects and
Externí odkaz:
https://doaj.org/article/4866fced8ba64f3cbfd41c2056d07b2c
Autor:
Henriett Butz, Éva Saskői, Lilla Krokker, Viktória Vereczki, Alán Alpár, István Likó, Erika Tóth, Erika Szőcs, Mihály Cserepes, Katalin Nagy, Imre Kacskovics, Attila Patócs
Publikováno v:
Cells, Vol 12, Iss 5, p 784 (2023)
Background. The dual role of GCs has been observed in breast cancer; however, due to many concomitant factors, GR action in cancer biology is still ambiguous. In this study, we aimed to unravel the context-dependent action of GR in breast cancer. Met
Externí odkaz:
https://doaj.org/article/f58999a2c3d24be8b480e8bb5c8bb000
Autor:
Zsófia I. László, Zsolt Lele, Miklós Zöldi, Vivien Miczán, Fruzsina Mógor, Gabriel M. Simon, Ken Mackie, Imre Kacskovics, Benjamin F. Cravatt, István Katona
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
During embryonic development, neural progenitor cells undergo numerous cell divisions. Here, the authors show that ABHD4-mediated developmental anoikis distinguishes the physiological delamination and the pathological detachment of progenitor cells w
Externí odkaz:
https://doaj.org/article/62189b9ad70741068eea632e23f22e26
Autor:
Bence Szikora, Anita Marx, Péter K. Jani, Orsolya Pipek, Viktor Müller, István Csabai, Imre Kacskovics
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The neonatal Fc receptor (FcRn) plays key roles in IgG and albumin homeostasis, maternal IgG transport, and antigen presentation of IgG-opsonized antigens. Previously, we reported that transgenic (Tg) mice that overexpress bovine FcRn (bFcRn) have au
Externí odkaz:
https://doaj.org/article/7d996e0564bc481e90e208f598eb8d9d
Autor:
Martin Vaeth, Jun Yang, Megumi Yamashita, Isabelle Zee, Miriam Eckstein, Camille Knosp, Ulrike Kaufmann, Peter Karoly Jani, Rodrigo S. Lacruz, Veit Flockerzi, Imre Kacskovics, Murali Prakriya, Stefan Feske
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Ca2+ release-activated Ca2+(CRAC) channels are essential for protective immunity, but the immunological functions of the three ORAI homologues that form CRAC channels are unclear. Here the authors show that ORAI1 and ORAI2 form heteromeric CRAC chann
Externí odkaz:
https://doaj.org/article/cecf348141a04e5d97c610a4720fbbd4
Autor:
Imre Kacskovics
Publikováno v:
Scientia et Securitas. 2:200-206
Összefoglaló. A SARS-CoV-2 koronavírus által kiváltott pandémia az elmúlt mintegy 100 év legsúlyosabb közegészségügyi, gazdasági és társadalmi válságát okozza. Az emberiség soha nem látott tudással, példa nélküli sebességgel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70cf31957d8ee29eb4f173cacf6f96f
https://doi.org/10.1556/112.2021.00047
https://doi.org/10.1556/112.2021.00047
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185662 (2017)
Despite the increasing importance of rabbit as an animal model in pharmacological studies like investigating placental transfer of therapeutic IgGs, little is known about the molecular interaction of the rabbit neonatal Fc receptor (FcRn) with rabbit
Externí odkaz:
https://doaj.org/article/28b3c536f66240b08cc7c0041c6b7ce2
Autor:
Gábor E. Tusnády, György Várady, Dóra Dedinszki, András Váradi, Eszter Kozák, Bence Szikora, Natália Tőkési, Attila Iliás, Viola Pomozi, Zoltán Hegyi, Péter K. Jani, Éva Bakos, Krisztina Fülöp, Imre Kacskovics, Zsolt Matula
Publikováno v:
FEBS Letters. 595:789-798
Mutations in the ABCC6 gene result in calcification diseases such as pseudoxanthoma elasticum or Generalized Arterial Calcification of Infancy. Generation of antibodies recognizing an extracellular (EC) epitope of ABCC6 has been hampered by the short
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e047e5d7083ef45e70d902374dfff69a
https://doi.org/10.1002/1873-3468.13991
https://doi.org/10.1002/1873-3468.13991