Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Imogen R. Brooks"'
Autor:
Adam Sheriff, Ina Guri, Paulina Zebrowska, Virginia Llopis-Hernandez, Imogen R. Brooks, Stavroula Tekkela, Kavita Subramaniam, Ruta Gebrezgabher, Gaetano Naso, Anastasia Petrova, Katarzyna Balon, Alexandros Onoufriadis, Dorota Kujawa, Martyna Kotulska, Gregory Newby, Łukasz Łaczmański, David R. Liu, John A. McGrath, Joanna Jacków
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Base editing introduces precise single-nucleotide edits in genomic DNA and has the potential to treat genetic diseases such as the blistering skin disease recessive dystrophic epidermolysis bullosa (RDEB), which is characterized by mutations
Externí odkaz:
https://doaj.org/article/03e319002a21459e8249bcc2341dc40e
Autor:
Brenda Y. Han, Michelle K. Y. Seah, Imogen R. Brooks, Delia H. P. Quek, Dominic R. Huxley, Chuan-Sheng Foo, Li Ting Lee, Heike Wollmann, Huili Guo, Daniel M. Messerschmidt, Ernesto Guccione
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
PRDM family members are transcriptional regulators involved in cell identity and fate determination. Here, the authors characterize PRDM10 and show that it functions to ensure global translation efficiency during early embryonic development.
Externí odkaz:
https://doaj.org/article/e7989e77dc6240d282d3dcdcea55b0b3
Autor:
Steven Woods, Paul A. Humphreys, Nicola Bates, Sophie Alice Richardson, Shweta Yogesh Kuba, Imogen R. Brooks, Stuart A. Cain, Susan J. Kimber
Publikováno v:
Cells, Vol 10, Iss 4, p 726 (2021)
The growth factor TGFβ and the mechanosensitive calcium-permeable cation channel TRPV4 are both important for the development and maintenance of many tissues. Although TRPV4 and TGFβ both affect core cellular functions, how their signals are integr
Externí odkaz:
https://doaj.org/article/1d774b9a8d4c45f196972627bb5f0129
Publikováno v:
International Journal of Molecular Sciences. 24:2298
Genodermatoses encompass a wide range of inherited skin diseases, many of which are monogenic. Genodermatoses range in severity and result in early-onset cancers or life-threatening damage to the skin, and there are few curative options. As such, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c399fc91b303f20b9774a3aa000744e4
https://doi.org/10.3390/ijms24032298
https://doi.org/10.3390/ijms24032298
Autor:
Imogen R. Brooks, Cristina M. Garrone, Caoimhe Kerins, Cher Shen Kiar, Sofia Syntaka, Jessie Z. Xu, Francesca M. Spagnoli, Fiona M. Watt
Publikováno v:
Stem cell reports. 17(5)
Induced pluripotent stem cells (iPSCs) are valuable in disease modeling because of their potential to expand and differentiate into virtually any cell type and recapitulate key aspects of human biology. Functional genomics are genome-wide studies tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec425bf5b43d8d3e02cf44cb198f4aff
https://pubmed.ncbi.nlm.nih.gov/35487213
https://pubmed.ncbi.nlm.nih.gov/35487213
Autor:
Sophie Alice Richardson, Nicola Bates, Shweta Yogesh Kuba, Susan J. Kimber, Imogen R. Brooks, Steven Woods, Stuart A. Cain, Paul A. Humphreys
Publikováno v:
Woods, S, Humphreys, P, Bates, N, Richardson, S, Kuba, S Y, Brooks, I, Cain, S & Kimber, S 2021, ' Regulation of TGF beta Signalling by TRPV4 in Chondrocytes ', Cell, vol. 10, no. 4, 726 . https://doi.org/10.3390/cells10040726
Cells, Vol 10, Iss 726, p 726 (2021)
Cells
Volume 10
Issue 4
Cells, Vol 10, Iss 726, p 726 (2021)
Cells
Volume 10
Issue 4
The growth factor TGFβ and the mechanosensitive calcium-permeable cation channel TRPV4 are both important for the development and maintenance of many tissues. Although TRPV4 and TGFβ both affect core cellular functions, how their signals are integr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec091390d7e66e6c77086bdb24b07a3
https://www.research.manchester.ac.uk/portal/en/publications/regulation-of-tgf-beta-signalling-by-trpv4-in-chondrocytes(0cb5a9a5-c5e4-4530-8178-e1b37c123cb2).html
https://www.research.manchester.ac.uk/portal/en/publications/regulation-of-tgf-beta-signalling-by-trpv4-in-chondrocytes(0cb5a9a5-c5e4-4530-8178-e1b37c123cb2).html
