Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Immunotherapy/methods"'
Publikováno v:
Arquivos Brasileiros de Oftalmologia, Issue: ahead, Published: 24 MAR 2023
Purpose: Opsoclonus-myoclonus syndrome is extremely uncommon in adults with an autoimmune pathophysiology. Because of the rarity of the syndrome, international recognition of opsoclonus-myoclonus-ataxia syndrome needs to be improved urgently. Therefo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______608::fefd271194598fb2c6d99f11fb171aa8
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492023005002304&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492023005002304&lng=en&tlng=en
Autor:
Pfefferlé, Marc, Dubach, Irina L, Buzzi, Raphael M, Dürst, Elena, Schulthess-Lutz, Nadja, Baselgia, Livio, Hansen, Kerstin, Imhof, Larissa, Koernig, Sandra, Le Roy, Didier, Roger, Thierry, Humar, Rok, Schaer, Dominik J, Vallelian, Florence
Publikováno v:
Journal for immunotherapy of cancer, vol. 11, no. 1, pp. e005718
BackgroundAgonistic anti-CD40 monoclonal antibodies (mAbs) have emerged as promising immunotherapeutic compounds with impressive antitumor effects in mouse models. However, preclinical and clinical studies faced dose-limiting toxicities mediated by n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1069a3f48716c4418a15a2ff93f58635
https://serval.unil.ch/resource/serval:BIB_255273ACC947.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_255273ACC947.P001/REF.pdf
Autor:
Paolo A. Ascierto, Sanjiv S. Agarwala, Christian Blank, Corrado Caracò, Richard D. Carvajal, Marc S. Ernstoff, Soldano Ferrone, Bernard A. Fox, Thomas F. Gajewski, Claus Garbe, Jean-Jacques Grob, Omid Hamid, Michelle Krogsgaard, Roger S. Lo, Amanda W. Lund, Gabriele Madonna, Olivier Michielin, Bart Neyns, Iman Osman, Solange Peters, Poulikos I. Poulikakos, Sergio A. Quezada, Bradley Reinfeld, Laurence Zitvogel, Igor Puzanov, Magdalena Thurin
Publikováno v:
Journal of translational medicine. 20(1)
Advances in immune checkpoint and combination therapy have led to improvement in overall survival for patients with advanced melanoma. Improved understanding of the tumor, tumor microenvironment and tumor immune-evasion mechanisms has resulted in new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d60655e5ab2acc03da373e29125ce7
https://pubmed.ncbi.nlm.nih.gov/36058945
https://pubmed.ncbi.nlm.nih.gov/36058945
Autor:
Ze'ev Ronai, Leonard I. Zon, Carmit Levy, Meenhard Herlyn, Marcus Bosenberg, Amanda W. Lund, David B. Lombard, Jean-Christophe Marine, Richard M. White, Yardena Samuels, Charles K. Kaufman, Christin E. Burd, Shaheen Khan, Marc Hurlbert, Kristen L. Mueller, Eleonora Leucci, Andrew E. Aplin, Sheri L. Holmen, Iwei Yeh, Ashani T. Weeraratna, David J. Adams, Martin McMahon, Corine Bertolotto, Florian A. Karreth, Sebastian Kobold, Glenn Merlino, Carla Daniela Robles-Espinoza, Ping Chi, Jessie Villanueva, Niroshana Anandasabapathy, Kerrie L. Marie, Maria S. Soengas, Jiyue Zhu, Richard Marais, Craig J. Ceol, E. Elizabeth Patton
Publikováno v:
Patton, E E, Mueller, K L, Adams, D J, Anandasabapathy, N, Aplin, A E, Bertolotto, C, Bosenberg, M, Ceol, C, Chi, P, Herlyn, M, Holmen, S L, Karreth, F A, Kaufman, C, Khan, S, Kobold, S, Leucci, E, Levy, C, Lombard, D B, Lund, A W, Marie, K L, Marine, J-C, Marais, R, McMahon, M, Robles-Espinoza, C D, Ronai, Z A, Samuels, Y, Soengas, M S, Villanueva, J, Weeraratna, A T, White, R M, Yeh, I, Zhu, J, Zon, L I, Hurlbert, M S & Merlino, G 2021, ' Melanoma Models for the Next Generation of Therapies ', Cancer Cell . https://doi.org/10.1016/j.ccell.2021.01.011
Cancer Cell
Patton, E E, Mueller, K L, Adams, D J, Anandasabapathy, N, Aplin, A E, Bertolotto, C, Bosenberg, M, Ceol, C J, Burd, C E, Chi, P, Herlyn, M, Holmen, S L, Karreth, F A, Kaufman, C K, Khan, S, Kobold, S, Leucci, E, Levy, C, Lombard, D B, Lund, A W, Marie, K L, Marine, J-C, Marais, R, McMahon, M, Robles-Espinoza, C D, Ronai, Z A, Samuels, Y, Soengas, M S, Villanueva, J, Weeraratna, A T, White, R M, Yeh, I, Zhu, J, Zon, L I, Hurlbert, M S & Merlino, G 2021, ' Melanoma models for the next generation of therapies ', Cancer Cell, vol. 39, no. 5, pp. 610-631 . https://doi.org/10.1016/j.ccell.2021.01.011
Cancer Cell
Patton, E E, Mueller, K L, Adams, D J, Anandasabapathy, N, Aplin, A E, Bertolotto, C, Bosenberg, M, Ceol, C J, Burd, C E, Chi, P, Herlyn, M, Holmen, S L, Karreth, F A, Kaufman, C K, Khan, S, Kobold, S, Leucci, E, Levy, C, Lombard, D B, Lund, A W, Marie, K L, Marine, J-C, Marais, R, McMahon, M, Robles-Espinoza, C D, Ronai, Z A, Samuels, Y, Soengas, M S, Villanueva, J, Weeraratna, A T, White, R M, Yeh, I, Zhu, J, Zon, L I, Hurlbert, M S & Merlino, G 2021, ' Melanoma models for the next generation of therapies ', Cancer Cell, vol. 39, no. 5, pp. 610-631 . https://doi.org/10.1016/j.ccell.2021.01.011
Summary There is a lack of appropriate melanoma models that can be used to evaluate the efficacy of novel therapeutic modalities. Here, we discuss the current state of the art of melanoma models including genetically engineered mouse, patient-derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9caa7c8db82a369339ccaae359006a1d
https://doi.org/10.1016/j.ccell.2021.01.011
https://doi.org/10.1016/j.ccell.2021.01.011
Publikováno v:
Journal of Experimental & Clinical Cancer Research. 41(1)
Cholangiocarcinoma (CCA) is the second most common primary liver cancer and associated with a dismal prognosis due to the lack of an efficient systemic therapy. In contrast to other cancers, new immunotherapies have demonstrated unsatisfactory result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od________83::09c8f9d4213ce71ddbd03c87e2b0f717
https://cris.maastrichtuniversity.nl/en/publications/b430e385-472a-4247-82d3-ec7d1f8a47f3
https://cris.maastrichtuniversity.nl/en/publications/b430e385-472a-4247-82d3-ec7d1f8a47f3
Akademický článek
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Autor:
Christian H. Wetzel, Hartmut Goldschmidt, Vladimir M. Milenkovic, Mark Berneburg, Mathias Witzens-Harig, György Vereb, Ayse Nur Menevse, Arpad Szoor, Michael Boutros, Antonio Sorrentino, Chih-Yeh Chen, Anchana Rathinasamy, Philipp Beckhove, Sebastian Haferkamp, Klaus G. Griewank, Martin Ehrenschwender, Gertrud Knoll, Tillmann Michels, Madlen Ditz, Valentina Volpin, Anja Seckinger, Dirk Hose, Nisit Khandelwal
Publikováno v:
Cancer Immunology Research. 8:1163-1179
The success of cancer immunotherapy is limited by resistance to immune checkpoint blockade. We therefore conducted a genetic screen to identify genes that mediated resistance against CTLs in anti–PD-L1 treatment–refractory human tumors. Using PD-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff975b35c4053903783cb9175f1f3d58
https://doi.org/10.1158/2326-6066.cir-19-0608
https://doi.org/10.1158/2326-6066.cir-19-0608
Presents timely and authoritative information on the development of precision cancer therapies as applied to hematologic malignancies The Precision Cancer Therapies series focuses on how to understand and translate fundamental basic science into info
Akademický článek
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Autor:
Jacques Neefjes, Anastasia Xagara, Johannes B. Huppa, Matthijs Raaben, Sophie Bliss, Xiangrui Kong, Elmer Stickel, Mirjam H.M. Heemskerk, Tao Zhang, Hermen S. Overkleeft, Stephanie Holst, Soldano Ferrone, Birol Cabukusta, Vincent A. Blomen, Manfred Wuhrer, Thijn R. Brummelkamp, Antonius A. de Waard, Carolin Gerke, Anne Halenius, René Platzer, Lennert Janssen, Rosina Plomp, Marlieke L.M. Jongsma, Arend Mulder, Tamara Verkerk, Frans H.J. Claas, Marieke Griffioen, Robbert M. Spaapen
Publikováno v:
Immunity
Immunity, 54(1), 132-150.e9. Cell Press
Immunity, 54(1), 132-150.e9. CELL PRESS
Immunity, 54(1), 132-150.e9. Cell Press
Immunity, 54(1), 132-150.e9. CELL PRESS
HLA class I (HLA-I) glycoproteins drive immune responses by presenting antigens to cognate CD8+ T cells. This process is often hijacked by tumors and pathogens for immune evasion. Because options for restoring HLA-I antigen presentation are limited,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc52593816d0dbe9f26a66bfd1bf047
https://europepmc.org/articles/PMC8722104/
https://europepmc.org/articles/PMC8722104/