Zobrazeno 1 - 10
of 379
pro vyhledávání: '"Immunosuppressive tumor microenvironment"'
Autor:
Fusheng Zhang, Junchen Guo, Shengmiao Yu, Youwei Zheng, Meiqi Duan, Liang Zhao, Yihan Wang, Zhi Yang, Xiaofeng Jiang
Publikováno v:
Cancer Communications, Vol 44, Iss 9, Pp 929-966 (2024)
Abstract The intrinsic oncogenic mechanisms and properties of the tumor microenvironment (TME) have been extensively investigated. Primary features of the TME include metabolic reprogramming, hypoxia, chronic inflammation, and tumor immunosuppression
Externí odkaz:
https://doaj.org/article/bc02869ac1514f169afa31488a9900b7
Autor:
Hang Zhou, Chunyan Zhu, Qing Zhao, Jinliang Ni, Haipeng Zhang, Guangcan Yang, Jianchao Ge, Chao Fang, Hong Wei, Xianli Zhou, Kun Zhang
Publikováno v:
Bioactive Materials, Vol 39, Iss , Pp 14-24 (2024)
Tumor-promoting niche after incomplete surgery resection (SR) can lead to more aggressive local progression and distant metastasis with augmented angiogenesis-immunosuppressive tumor microenvironment (TME). Herein, elevated neutrophil extracellular t
Externí odkaz:
https://doaj.org/article/48873ab7a8ff48abb5c3774a7907d32f
Autor:
Yue Yin, Weibo Feng, Jie Chen, Xilang Chen, Guodong Wang, Shuai Wang, Xiao Xu, Yongzhan Nie, Daiming Fan, Kaichun Wu, Limin Xia
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-37 (2024)
Abstract Hepatocellular carcinoma (HCC) is a highly heterogeneous malignancy with high incidence, recurrence, and metastasis rates. The emergence of immunotherapy has improved the treatment of advanced HCC, but problems such as drug resistance and im
Externí odkaz:
https://doaj.org/article/0bb3d6de27e94bdf85c10ed6e6550ff6
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Cuproptosis is a novel type to regulate cell death with copper-dependent manner, and has been reported to involve in the occurrence and development of various malignant tumors. However, the association between cuproptosis and the tumor micro
Externí odkaz:
https://doaj.org/article/79e18b7957b24bc5bc2e08dfdaa2865b
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 6619-6641 (2024)
Xuan Pan,1,* Ting Han,2,* Zixuan Zhao,3,4 Xiaoming Wang,1 Xiaosan Fang1 1Department of Hepato-Biliary-Pancreatic Surgery, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, 241000, Peo
Externí odkaz:
https://doaj.org/article/cb70d119d8a94881ba70a163bef6c28c
Autor:
Yuxuan Peng, Shuang Liang, Dan Liu, Kongshuo Ma, Kaiqing Yun, Mengli Zhou, Linna Hai, Mengdi Xu, Yiyang Chen, Zhaohui Wang
Publikováno v:
Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)
Abstract The highly immunosuppressive tumor microenvironment (TME) restricts the efficient activation of immune responses. To restore the surveillance of the immune system for robust activation, vast efforts are devoted to normalizing the TME. Here,
Externí odkaz:
https://doaj.org/article/868a72428d9646aea2a71d7583aa3e40
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3780-3782 (2024)
Externí odkaz:
https://doaj.org/article/386b9bc9ee8b4ace93403357dc832e7d
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundClear cell renal cell carcinoma (ccRCC) poses substantial treatment challenges, especially in advanced stages where the efficacy of immune checkpoint blockade (ICB) therapy varies significantly. Elevated expression of the oncogene TUBA1C ha
Externí odkaz:
https://doaj.org/article/7879d0fe4fd146228a6bd10256a32afd
Autor:
Honglin Huang, Ningxi Li, Xiaodan Wei, Qingzhi Li, Junhan Guo, Geng Yang, Hong Yang, Lulu Cai, Yiyao Liu, Chunhui Wu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 3, Pp 1345-1361 (2024)
A novel strategy of not only stimulating the immune cycle but also modulating the immunosuppressive tumor microenvironment is of vital importance to efficient cancer immunotherapy. Here, a new type of spatiotemporal biomimetic “Gemini nanoimmunoreg
Externí odkaz:
https://doaj.org/article/4af792f9e05b4172917120374542fe81
Publikováno v:
In Molecular Therapy December 2024