Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Immunosuppressive Agents/pharmacology"'
Autor:
Mario Habek, Koraljka Đurić, Alenka Horvat Ledinek, Ivana Lapić, Tereza Gabelić, Nevena Grbić, Gregor Jakob Brecl, Dunja Rogić, Vanja Bašić Kes, Ivan Adamec, Magdalena Krbot Skorić, Andreja Emeršič, Dragana Šegulja, Barbara Barun
Publikováno v:
Journal of Neuroimmunology
Aim To determine the influence of high-efficacy disease modifying therapy (DMT) on the development of IgG SARS-CoV-2 antibody response in COVID-19 convalescent people with multiple sclerosis (pwMS). Methods Seventy-four pwMS taking high-efficacy DMTs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23727aafa3f2fce8621d988211ff9593
https://urn.nsk.hr/urn:nbn:hr:105:017413
https://urn.nsk.hr/urn:nbn:hr:105:017413
Autor:
Lakshmi Narayanan, Simon M. Firestone, Todd M. Archer, Caroline S Mansfield, Julien R.S. Dandrieux
Publikováno v:
Dandrieux, J R S, Narayanan, L, Firestone, S, Archer, T M & Mansfield, C S 2019, ' Effect of immunosuppressive drugs on cytokine production in canine whole blood stimulated with lipopolysaccharide or a combination of ionomycin and phorbol 12-myristate 13-acetate ', Veterinary Medicine and Science, vol. 5, no. 2, pp. 199-205 . https://doi.org/10.1002/vms3.143
Veterinary Medicine and Science
Veterinary Medicine and Science
A pharmacodynamic assay has been previously developed to monitor ciclosporin treatment in dogs by assessing inhibition of cytokine transcription after whole blood stimulation with 12‐myristate 13‐1 acetate and ionomycin (PMA/I). In this study, wh
Autor:
Stefan Diem, Oltin T Pop, Joachim Müller, Alexandre Moulin, Sandra S. Ring, Omar Ali, Stefanie Müller, Lukas Flatz, Christoph Jakob Ackermann, Thomas Hundsberger, Fiamma Berner, Eva Markert
Publikováno v:
Cancer immunology, immunotherapy, vol. 70, no. 2, pp. 563-568
Cancer Immunology, Immunotherapy
Cancer Immunology, Immunotherapy
Immune checkpoint inhibitors (ICIs) are emerging as the new standard of care for treating various metastatic cancers. It is known that effective anti-tumor immune responses are associated with a stronger presence of tumor-infiltrating lymphocytes (TI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50dff028bc2af180e99598e3d2894abb
https://serval.unil.ch/notice/serval:BIB_57755DC2151E
https://serval.unil.ch/notice/serval:BIB_57755DC2151E
Autor:
Christopher J.R. Dunning, Tomas Deierborg, Bettina Hjelm Clausen, Yiyi Yang, Antonio Boza-Serrano, Kate Lykke Lambertsen
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-19 (2018)
Journal of Neuroinflammation
Yang, Y, Boza-Serrano, A, Dunning, C J R, Clausen, B H, Lambertsen, K L & Deierborg, T 2018, ' Inflammation leads to distinct populations of extracellular vesicles from microglia ', Journal of Neuroinflammation, vol. 15, 168 . https://doi.org/10.1186/s12974-018-1204-7
Journal of Neuroinflammation
Yang, Y, Boza-Serrano, A, Dunning, C J R, Clausen, B H, Lambertsen, K L & Deierborg, T 2018, ' Inflammation leads to distinct populations of extracellular vesicles from microglia ', Journal of Neuroinflammation, vol. 15, 168 . https://doi.org/10.1186/s12974-018-1204-7
Background Activated microglia play an essential role in inflammatory responses elicited in the central nervous system (CNS). Microglia-derived extracellular vesicles (EVs) are suggested to be involved in propagation of inflammatory signals and in th
Publikováno v:
Clinical Science, Vol. 129, No 10 (2015) pp. 895-914
Clinical science (London England : 1979)
Clinical science (London England : 1979)
mTOR (mechanistic target of rapamycin) functions as the central regulator for cell proliferation, growth and survival. Up-regulation of proteins regulating mTOR, as well as its downstream targets, has been reported in various cancers. This has promot
Autor:
Soumaya Marzouki, Melika Ben Ahmed, Jihene Bettaieb, Ines Bini Dhouib, Saloua El Fazaa, Chaouki Benabdessalem, Ammar Maroueni, Mohamed-Ridha Barbouche, Zakaria Bellasfar, Raoudha Doghri, Raja Rekik
Publikováno v:
Life Sciences
Life Sciences, Elsevier, 2018, 188, pp.10-16. ⟨10.1016/j.lfs.2017.08.022⟩
Life Sciences, Elsevier, 2018, 188, pp.10-16. ⟨10.1016/j.lfs.2017.08.022⟩
Aims Acetamiprid (ACE) is an insecticide of the neonicotinoid family, the most widely used in the world. Herein, we assessed the effect of ACE on either the humoral or cellular immune responses of rodents. We also evaluated the role of curcumin in th
Publikováno v:
Steeples, L R, Spry, P, Lee, R W J & Carreño, E 2018, ' Adalimumab in refractory cystoid macular edema associated with birdshot chorioretinopathy ', International Ophthalmology, vol. 38, no. 3, pp. 1357-1362 . https://doi.org/10.1007/s10792-017-0592-5
PURPOSE: To report the clinical outcomes of adalimumab therapy in cases of birdshot chorioretinitis (BCR) with cystoid macular edema (CME) refractory to conventional immunotherapy.METHODS: This is a retrospective case series of three BCR patients tre
Cytosine arabinoside (ARA-C) is a pyrimidine analog that may cause keratoconjunctivitis when used in high doses. The underlying mechanism may be the increased amounts of reactive oxygen radicals that may damage the DNA synthesis of corneal and conjun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3566::d632ab8dbc851ae9f31e25ec3c6a485c
Autor:
Philippe Morel, Laurianne Giovannoni, Thierry Berney, Nadja Niclauss, Géraldine Parnaud, Domenico Bosco
Publikováno v:
Transplantation, Vol. 91, No 7 (2011) pp. 714-22
The cause for a progressive attrition of islet graft function observed over the years after islet transplantation is not well defined but may be in part the result of adverse effects of immunosuppressive agents. In this study, we examined the effect
Autor:
Ralf Ludwig, Katja Hardt, Roland Kaufmann, Josef Pfeilschifter, Simone A. Rubant, Sandra Diehl, Wolf-Henning Boehncke
Publikováno v:
Journal of Investigative Dermatology, Vol. 128, No 2 (2008) pp. 326-331
Esters of fumaric acid have a long tradition in the treatment of psoriasis. Dimethylfumarate (DMF) is perceived as the main active substance. However, the molecular mechanisms of DMF action are not completely understood. Here, we investigate the effe