Zobrazeno 1 - 10
of 6 242
pro vyhledávání: '"Immunometabolism"'
Autor:
Leonel Witcoski Junior, Jordana Dinorá de Lima, Amanda Girardi Somensi, Lucas Brito de Souza Santos, Giulia Leonel Paschoal, Thalita Suemy Uada, Thais Sibioni Berti Bastos, André Guilherme Portela de Paula, Rebeca Bosso Dos Santos Luz, Andressa Pacheco Czaikovski, Mariana Rodrigues Davanso, Tarcio Teodoro Braga
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-10 (2024)
Abstract Type 2 diabetes (T2D) is associated with insulin resistance and progressive dysfunction of β-pancreatic cells, leading to persistent hyperglycemia. Macrophages play a crucial role in this context, influencing both the development and progre
Externí odkaz:
https://doaj.org/article/1165e7196a844a2a86432e184482cbec
Autor:
Yujing Sun, Zhenhua Zhang, Qincheng Qiao, Ying Zou, Lina Wang, Tixiao Wang, Bo Lou, Guosheng Li, Miao Xu, Yanxiang Wang, Zhenhong Zhang, Xinguo Hou, Li Chen, Ruxing Zhao
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract The pathogenesis of Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) remains unclear, though increasing evidence suggests inflammatory processes play key roles. In this study, single-cell RNA sequencing (scRNA-seq) of peripheral b
Externí odkaz:
https://doaj.org/article/8ea964cfb0db40a2882660eb63ef2a0b
Autor:
Kathryn W. Kesler, Angel Abuelo
Publikováno v:
Journal of Dairy Science, Vol 107, Iss 10, Pp 8378-8386 (2024)
ABSTRACT: The inability of dairy calves to fully respond to immune stimuli until they reach maturity at 6 mo of age severely limits the use of parenteral vaccines to protect calves against disease. Immune responses are metabolically demanding, and im
Externí odkaz:
https://doaj.org/article/a72875d1b0db449d9e659969e517ddab
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-23 (2024)
Abstract Lung diseases triggered by endogenous or exogenous factors have become a major concern, with high morbidity and mortality rates, especially after the coronavirus disease 2019 (COVID-19) pandemic. Inflammation and an over-activated immune sys
Externí odkaz:
https://doaj.org/article/2f56b0c6873b41948fd441a1b266fa9a
Autor:
Chima V. Maduka, Ashley V. Makela, Anthony Tundo, Evran Ural, Katlin B. Stivers, Maxwell M. Kuhnert, Mohammed Alhaj, Ehsanul Hoque Apu, Nureddin Ashammakhi, Kurt D. Hankenson, Ramani Narayan, Jennifer H. Elisseeff, Christopher H. Contag
Publikováno v:
Bioactive Materials, Vol 40, Iss , Pp 64-73 (2024)
Composite biomaterials comprising polylactide (PLA) and hydroxyapatite (HA) are applied in bone, cartilage and dental regenerative medicine, where HA confers osteoconductive properties. However, after surgical implantation, adverse immune responses t
Externí odkaz:
https://doaj.org/article/409df55790de48dda2d0a7d4616cfc98
Autor:
Signe Mosegaard, Krishna S. Twayana, Simone W. Denis, Jeffrey Kroon, Bauke V. Schomakers, Michel vanWeeghel, Riekelt H. Houtkooper, Rikke K. J. Olsen, Christian K. Holm
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 9, Pp 337-350 (2024)
Abstract Stimulation of mammalian cells with inflammatory inducers such as lipopolysaccharide (LPS) leads to alterations in activity of central cellular metabolic pathways. Interestingly, these metabolic changes seem to be important for subsequent re
Externí odkaz:
https://doaj.org/article/7938490e07d84a48856606bf02802cfc
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-32 (2024)
Abstract Metabolic reprogramming drives the development of an immunosuppressive tumor microenvironment (TME) through various pathways, contributing to cancer progression and reducing the effectiveness of anticancer immunotherapy. However, our underst
Externí odkaz:
https://doaj.org/article/3b42e5bd71364a169460ec7c42977dda
Autor:
Chao Fang, Pan Ren, Yejun He, Yitian Wang, Shuting Yao, Congying Zhao, Xueyong Li, Xi Zhang, Jinqing Li, Mingkai Li
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Mitochondria play a crucial role in shaping the macrophage inflammatory response during bacterial infections. Spinster homolog 2 (Spns2), responsible for sphingosine-1-phosphate (S1P) secretion, acts as a key regulator of mitochon
Externí odkaz:
https://doaj.org/article/02762005b86d49e084263462486c2033
Publikováno v:
Nanotechnology Reviews, Vol 13, Iss 1, Pp 209-49 (2024)
Immunotherapy is currently the main treatment for malignant tumors by activating immune cell. Metabolic reprogramming in tumor microenvironment can greatly affect the function of immune cell, and T cell is the main anti-tumor effector cell. Therefore
Externí odkaz:
https://doaj.org/article/b2362cf7e66e4ad39a023c102c62d1a5
Autor:
A. Amato, L. Liotta, C. Cavallo, C. L. Randazzo, A. Pino, S. Bonacci, M. Frisina, A. Procopio, F. Litrenta, V. Floridia, A. R. Di Rosa, M. Oteri, E. Trevisi, V. Lopreiato
Publikováno v:
Italian Journal of Animal Science, Vol 23, Iss 1, Pp 1069-1090 (2024)
The aim of this study was to evaluate the effects of supplementing OC enriched in polyphenols (EOC) to mid-lactating Holstein cows on milk quality, metabolic response, and rumen fermentation and microbiota. Twenty multiparous Holstein dairy cows (10
Externí odkaz:
https://doaj.org/article/74c7d5ffe2f54a058c4c4b2b963a28ef