Zobrazeno 1 - 10
of 930
pro vyhledávání: '"Immunology in the medical area"'
Autor:
Marco Mannes, Rebecca Halbgebauer, Lisa Wohlgemuth, David Alexander Christian Messerer, Susa Savukoski, Anke Schultze, Bettina Berger, Christiane Leonie Knapp, Christoph Q. Schmidt, Daniel Fürst, Morten Hillmer, Reiner Siebert, Oskar Eriksson, Barbro Persson, Bo Nilsson, Kristina Nilsson Ekdahl, Markus Huber-Lang
Publikováno v:
Journal of innate immunity, 15(1):412-427
The complement system plays a crucial role in host defense, homeostasis, and tissue regeneration and bridges the innate and the adaptive immune systems. Although the genetic variants in complement C2 (c.839_849+17del; p.(Met280Asnfs*5)) and C8B (c.16
Autor:
Anders Krifors, Elisabeth Freyhult, Mulki Rashid Teljebäck, Robert P. A. Wallin, Ola Winqvist, Emeli Månsson
Publikováno v:
Infectious Diseases. 55:142-148
Background: Vaccination against SARS-CoV-2 reduces the risk of hospitalisation and death, but vaccine-induced IgG antibodies against the spike protein (IgG S) decline over time. Less is known about the nature of the vaccine-induced T-cell response to
Publikováno v:
Frontiers in Immunology, 14:1145840. Frontiers Media SA
ObjectiveThe hyperinflammatory response, caused by severe acute respiratory syndrome-2 (SARS-CoV-2), is the most common cause of death in patients with coronavirus disease 2019 (COVID-19). The etiopathogenesis of this illness is not fully understood.
Autor:
Anna Sandström Gerdtsson, Mattis Knulst, Johan Botling, Artur Mezheyeuski, Patrick Micke, Sara Ek
Publikováno v:
Scientia
Immune infiltration; Spatial omics; Tertiary lymphoid structures Infiltración inmune; Ómica espacial; Estructuras linfoides terciarias Infiltració immune; Òmica espacial; Estructures limfoides terciàries The immune microenvironment of non-small
Autor:
Mark Chernyshev, Mrunal Sakharkar, Ruth I. Connor, Haley L. Dugan, Daniel J. Sheward, C. G. Rappazzo, Aron Stålmarck, Mattias N. E. Forsell, Peter F. Wright, Martin Corcoran, Ben Murrell, Laura M. Walker, Gunilla B. Karlsson Hedestam
Publikováno v:
Nature Communications. 14
Vaccination of SARS-CoV-2 convalescent individuals generates broad and potent antibody responses. Here, we isolate 459 spike-specific monoclonal antibodies (mAbs) from two individuals who were infected with the index variant of SARS-CoV-2 and later b
Publikováno v:
Frontiers in Cellular and Infection Microbiology. 13
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 148:2295-2311
Purpose Loss of expression of DLG2 has been identified in a number of cancers to contribute to the disease by resulting in increased tumor cell proliferation and poor survival. In light of the previous evidence that DLG2 alters the cell cycle and aff
Autor:
Linda Wass, Hanne Quarsten, Per-Eric Lindgren, Pia Forsberg, Elisabet Skoog, Kenneth Nilsson, Christine Lingblom, Christine Wennerås
Publikováno v:
Medical Microbiology and Immunology. 211:133-141
Purpose The tick-borne bacterium Neoehrlichia mikurensis causes the infectious disease neoehrlichiosis in humans. Vascular endothelium is one of the target cells of the infection. Neoehrlichiosis patients with compromised B cell immunity present with
Autor:
Kedeye, Tuerxun, Kristine, Midtbö, Eva, Särndahl, Egor, Vorontsov, Roger, Karlsson, Alexander, Persson, Robert, Kruse, Daniel, Eklund
Publikováno v:
Journal of Leukocyte Biology. 112:679-692
Myeloid-derived suppressor cells (MDSCs) are functionally immunosuppressive cellsthat arise and expand during extensive inflammatory conditions by increasedhematopoietic output or reprogramming of immune cells. In sepsis, an increase of circulatingMD
Autor:
Ewa Maria Sroka, Mathilde Lavigne, Marika Pla, Chrysoula Daskalogianni, Maria Camila Tovar-Fernandez, Rodrigo Prado Martins, Bénédicte Manoury, Guillaume Darrasse-Jéze, Megane Nascimento, Sebastien Apcher, Robin Fåhraeus
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (7), pp.e2208509120. ⟨10.1073/pnas.2208509120⟩
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (7), pp.e2208509120. ⟨10.1073/pnas.2208509120⟩
Antigenic peptides derived from introns are presented on major histocompatibility (MHC) class I molecules, but how these peptides are produced is poorly understood. Here, we show that an MHC class I epitope (SL8) sequence inserted in the second intro