Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Immunology/Allergy and Hypersensitivity"'
Interleukin-13 Promotes Susceptibility to Chlamydial Infection of the Respiratory and Genital Tracts
Autor:
Kenneth W. Beagley, Paul S. Foster, Alison J. Carey, Gerard E. Kaiko, Kelly L. Asquith, Philip M. Hansbro, Jay C. Horvat
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 5, p e1001339 (2011)
PLoS Pathogens, Vol 7, Iss 5, p e1001339 (2011)
Chlamydiae are intracellular bacteria that commonly cause infections of the respiratory and genital tracts, which are major clinical problems. Infections are also linked to the aetiology of diseases such as asthma, emphysema and heart disease. The cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3745d719d566d1c509a4452627895b33
https://hdl.handle.net/10453/128825
https://hdl.handle.net/10453/128825
Autor:
Brian O. Smith, Graeme Ball, Alan Cooper, Krystyna Bromek, Nicola Meenan, Malcolm W. Kennedy, Dušan Uhrín
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 4, p e1040 (2011)
PLoS Neglected Tropical Diseases
Meenan, N A G, Ball, G, Bromek, K, Uhrin, D, Cooper, A, Kennedy, M W & Smith, B O 2011, ' Solution Structure of a Repeated Unit of the ABA-1 Nematode Polyprotein Allergen of Ascaris Reveals a Novel Fold and Two Discrete Lipid-Binding Sites ', PLoS Neglected Tropical Diseases, vol. 5, no. 4, e1040, pp.-. https://doi.org/10.1371/journal.pntd.0001040
PLoS Neglected Tropical Diseases
Meenan, N A G, Ball, G, Bromek, K, Uhrin, D, Cooper, A, Kennedy, M W & Smith, B O 2011, ' Solution Structure of a Repeated Unit of the ABA-1 Nematode Polyprotein Allergen of Ascaris Reveals a Novel Fold and Two Discrete Lipid-Binding Sites ', PLoS Neglected Tropical Diseases, vol. 5, no. 4, e1040, pp.-. https://doi.org/10.1371/journal.pntd.0001040
Background Nematode polyprotein allergens (NPAs) are an unusual class of lipid-binding proteins found only in nematodes. They are synthesized as large, tandemly repetitive polyproteins that are post-translationally cleaved into multiple copies of sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e54fb6e5d15a32b512ce1addd9a940
http://europepmc.org/articles/PMC3079579?pdf=render
http://europepmc.org/articles/PMC3079579?pdf=render
Autor:
Sabine Altrichter, Martin Metz, Hans-Jürgen Peter, Dina Pisarevskaja, Marcus Maurer, Peter Martus
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e14794 (2011)
PLoS ONE
PLoS ONE
Background Chronic spontaneous urticaria (csU), which is characterized by recurrent episodes of mast cell-driven wheal and flare-type skin reactions, is often associated with elevated total IgE levels and thyroid autoimmunity. We speculate that some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962a6a86a852f196f0bb3126228cfc74
http://europepmc.org/articles/PMC3075251?pdf=render
http://europepmc.org/articles/PMC3075251?pdf=render
Autor:
Umesh C. S. Yadav, Istvan Boldogh, Kota V. Ramana, Leopoldo Aguilera-Aguirre, Satish K. Srivastava
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14440 (2010)
PLoS ONE
PLoS ONE
Background Goblet cell metaplasia that causes mucus hypersecretion and obstruction in the airway lumen could be life threatening in asthma and chronic obstructive pulmonary disease patients. Inflammatory cytokines such as IL-13 mediate the transforma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e37d07b73dd2f701800a8dcc67f224f4
http://europepmc.org/articles/PMC3010981?pdf=render
http://europepmc.org/articles/PMC3010981?pdf=render
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 11, p e14174 (2010)
PLoS ONE, Vol 5, Iss 11, p e14174 (2010)
Background Th2-dominated inflammatory response in the airway is an integral component in the pathogenesis of allergic asthma. Accumulating evidence supports the notion that the phosphoinositide 3-kinase (PI3K) pathway is involved in the process. We p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4554c352e4cfc4b8b647ae3a64ae136
http://europepmc.org/articles/PMC2994819
http://europepmc.org/articles/PMC2994819
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12204 (2010)
PLoS ONE
PLoS ONE
Background Elevated serum immunoglobulin (Ig) E is a diagnostic marker of immediate-type allergic reactions. We hypothesize that serum IgE does not necessarily reflect total body IgE because in vivo IgE can be bound to cell surface receptors such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ac2aa42949eef9c204101c7aa20bdf
http://europepmc.org/articles/PMC2922369?pdf=render
http://europepmc.org/articles/PMC2922369?pdf=render
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e11983 (2010)
PLoS ONE
PLoS ONE
Background Pertussis toxin (PTX), an exotoxin of Bordetella pertussis, enhances the development of experimental autoimmune diseases such as experimental autoimmune uveitis (EAU) and experimental autoimmune encephalomyelitis (EAE) in rodent models. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b91c7eef7fe2925817a728d7ddf9b20
http://europepmc.org/articles/PMC2916836?pdf=render
http://europepmc.org/articles/PMC2916836?pdf=render
Autor:
Emilie Bardel, Shizuo Akira, Abdulraouf Ramadan, Alejandro Gomez Alcala, Nathalie Thieblemont, Aude Aumeunier, Françoise Grela, Pascale Jeannin, Linh Pham Van, Jean-François Bach
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5, pp.e11484
PLoS ONE, Vol 5, Iss 7, p e11484 (2010)
PLoS ONE, Public Library of Science, 2010, 5, pp.e11484
PLoS ONE, Vol 5, Iss 7, p e11484 (2010)
BACKGROUND: Infections may be associated with exacerbation of allergic and autoimmune diseases. Paradoxically, epidemiological and experimental data have shown that some microorganisms can also prevent these pathologies. This observation is at the or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c468ac28b7d98b0c0dca10f9e08b471
http://europepmc.org/articles/PMC2900205
http://europepmc.org/articles/PMC2900205
Autor:
Steven Haenen, Vanessa De Vooght, Benoit Nemery, Peter Hoet, Jeroen Vanoirbeek, Katrien Luyts
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 9, p e12581 (2010)
PLoS ONE, Vol 5, Iss 9, p e12581 (2010)
BACKGROUND: The development of occupational asthma is the result of interactions between environmental factors and individual susceptibility. We assessed how our model of chemical-induced asthma is influenced by using different mouse strains. METHODO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f701c2aaf3a3660ededc4ef840fab0a
https://pubmed.ncbi.nlm.nih.gov/20830207
https://pubmed.ncbi.nlm.nih.gov/20830207
Autor:
Ulrich Pöschl, Gertie Janneke Oostingh, Erika Jensen-Jarolim, Regina Knittelfelder, Susanne C. Diesner, Otto Scheiner, Elisabeth Förster-Waldl, Cornelia Schultz, Philipp Starkl, Yingyi Zhang, Albert Duschl, Kathrin Selzle, Durga Krishnamurthy, Tobias Pfaller, Eva Untersmayr, Arnold Pollak
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 12, p e14210 (2010)
PLoS ONE, Vol 5, Iss 12, p e14210 (2010)
Background: Nitration of proteins on tyrosine residues, which can occur due to polluted air under “summer smog” conditions, has been shown to increase the allergic potential of allergens. Since nitration of tyrosine residues is also observed duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f19de96faf1af7d620138e468e003d
https://pubmed.ncbi.nlm.nih.gov/21151984
https://pubmed.ncbi.nlm.nih.gov/21151984