Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Immunologic receptor"'
Autor:
Robert L. Ferris, Yu Lei, Benedikt Höing, Benjamin A. Kansy, E Deuß, Cornelius H. L. Kürten, B Kramer, Stephan Lang
Publikováno v:
HNO. 68:916-921
CD8+-T-Effektor-Zellen spielen eine Schlusselrolle in der Identifikation und Elimination von Tumorzellen. Tumoren entkommen einer effektiven T‑Zell-Antwort durch Induktion eines Erschopfungszustands, der die zytotoxische Kapazitat der Effektorzelle
Autor:
Sandra Lara, André Perez-Potti, Laurent Adumeau, Yan Yan, Luciana M. Herda, Kenneth A. Dawson
Publikováno v:
ACS Nano. 12:4930-4937
Key practical challenges such as understanding the immunological processes at the nanoscale and controlling the targeting and accumulation of nano-objects in vivo now further stimulate efforts to underpin phenomenological knowledge of the nanoscale w
Akademický článek
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Autor:
Torres-Aguilar Honorio, Aguilar-Ruiz Sergio Roberto, Bustos-Arriaga José, Valle-Jiménez Xareni Raque, Ramírez-Cosmes Adriana, Sánchez-García Juan Carlos, Revilla-Rodríguez Eduardo, Romero-Tlalolini María de los Ángeles, Baltierrez-Hoyos Rafael
Publikováno v:
Immunological investigations. 47(2)
Sepsis is an organic dysfunction that puts at risk the life of patients suffering this disorder due to an exacerbated immunological response to the infection mediated by the host. Platelets have been largely researched on sepsis owing to its role in
Publikováno v:
Journal of the Neurological Sciences. 328:9-18
Fingolimod is the first oral disease-modifying therapy approved for relapsing forms of multiple sclerosis (MS). Following phosphorylation in vivo, the active agent, fingolimod phosphate (fingolimod-P), acts as a sphingosine 1-phosphate (S1P) receptor
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e51243 (2013)
PLoS ONE
PLoS ONE
Toll-like Receptors (TLR) are phylogenetically conserved transmembrane proteins responsible for detection of pathogens and activation of immune responses in diverse animal species. The stimulation of TLR by pathogen-derived molecules leads to the pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f08c89d83d04a6028ee864b1d2933787
https://doi.org/10.1371/journal.pone.0051243
https://doi.org/10.1371/journal.pone.0051243
Autor:
Yu Suzuki, Yoshiaki Yoshikawa, Yumie Ogasawara, Masahiko Muto, Takehiko Sasazuki, Yoshiaki Hamamoto, Kimi Ishikawa
Publikováno v:
Journal of Investigative Dermatology. 122:1133-1136
To elucidate the association between killer cell immunoglobulin-like receptors (KIRs) and psoriasis vulgaris (PV), we typed 14 KIR genes in 96 Japanese cases and 50 healthy controls using PCR with sequence-specific primers (PCR-SSP). Here we report a
Autor:
Siamon Gordon, Jurgen Herre, Janet A. Willment, Gordon D. Brown, Philip R. Taylor, David L. Williams
Publikováno v:
The Journal of Immunology. 172:1157-1162
We recently demonstrated that the β-glucan receptor Dectin-1 (βGR) was the major nonopsonic β-glucan receptor on macrophages (Mφ) for the yeast-derived particle zymosan. However, on resident peritoneal Mφ, we identified an additional mannan-inhi
Autor:
Erlene K. Seymour, Andrew D. Zelenetz, Kelly Piersanti, Carly G. K. Ziegler, Sami N. Malek, Jeffrey Gardner, Kurt S. Bantilan, Robert S. Balderas, M. Lia Palomba, Hugo Decker, Ivelise Rijo, Debra L Bemis, Jesse W. Cotari, Grégoire Altan-Bonnet, Mark L. Heaney, Marcel R.M. van den Brink
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e79987 (2014)
PLoS ONE
PLoS ONE
Purpose Chronic Lymphocytic Leukemia (CLL) is defined by a perturbed B-cell receptor-mediated signaling machinery. We aimed to model differential signaling behavior between B cells from CLL and healthy individuals to pinpoint modes of dysregulation.
Autor:
Siva Kumar Kolluri, Hyo Sang Jang, Jamie M. Pennington, Sumit Punj, Patrick L. Iversen, Diana Rohlman, Jessica Lynne Phillips, Prasad Rao Kopparapu, Edmond F. O’Donnell, Nancy I. Kerkvliet
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88726 (2014)
PLoS ONE
PLoS ONE
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that plays multiple roles in regulation of immune and inflammatory responses. The ability of certain AhR ligands to induce regulatory T cells (Tregs) has generated interes