Zobrazeno 1 - 10
of 784
pro vyhledávání: '"Immunologic Tolerance"'
Autor:
Fang Ke, Zachary L Benet, Mitra P Maz, Jianhua Liu, Alexander L Dent, Joanne Michelle Kahlenberg, Irina L Grigorova
Publikováno v:
eLife, Vol 12 (2023)
Follicular regulatory T cells (Tfr) restrict development of autoantibodies and autoimmunity while supporting high-affinity foreign antigen-specific humoral response. However, whether Tfr can directly repress germinal center (GC) B cells that acquire
Externí odkaz:
https://doaj.org/article/859bb3259706499e8d6e931c50a4ed50
Autor:
Susumu Eguchi, Mitsuhisa Takatsuki
Publikováno v:
Journal of Hepato-Biliary-Pancreatic Sciences. 29:369-376
BACKGROUND Immunosuppression is essential after organ transplantation to prevent severe graft injury due to rejection, but in long-term, transplanted organs are generally accepted with minimal dose of immunosuppression, and adverse effects of it such
Autor:
Brendan P. Lovasik
Publikováno v:
Transplantation. 104:1537-1541
This historical retrospective explores the study of the freemartin condition and its impact on the discovery of immunologic tolerance and the field of transplant surgery-from the ancient Romans, to early modern anatomists Valsalva, Scarpa, and Hunter
Autor:
Amr Mansouri, Siawosh K. Eskandari, Harvey Cantor, John Choi, Jamil Azzi, Melissa Y. Yeung, Eman Alhussain, Saif A. Muhsin, Songjie Cai, Hye-Jung Kim, Hazim Allos, Jean Pierre Assaker, Marc A. Seelen, Ina Sulkaj, Juliano B. Alhaddad
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, 117(11), 6042-6046. NATL ACAD SCIENCES
Proceedings of the National Academy of Sciences of the United States of America, 117(11), 6042-6046. NATL ACAD SCIENCES
Induction of longstanding immunologic tolerance is essential for survival of transplanted organs and tissues. Despite recent advances in immunosuppression protocols, allograft damage inflicted by antibody specific for donor organs continues to repres
Autor:
Paul E. Monahan, Leonard A. Valentino, Claude Negrier, Michael D. Tarantino, Federico Mingozzi
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 2471, p 2471 (2021)
Journal of Clinical Medicine
Journal of Clinical Medicine
Adeno-associated viral (AAV) vector gene therapy has shown promise as a possible cure for hemophilia. However, immune responses directed against AAV vectors remain a hurdle to the broader use of this gene transfer platform. Both innate and adaptive i
Autor:
Martin Penagos, Stephen R. Durham
Publikováno v:
Current Opinion in Allergy & Clinical Immunology. 19:594-605
PURPOSE OF REVIEW We evaluated the time-course of clinical and immunologic changes that occur during and after cessation of sublingual and subcutaneous allergen immunotherapy for inhalant allergies. RECENT FINDINGS Increases in production of inhibito
Autor:
Wilson de Melo Cruvinel, Danilo Mesquita Jr., Júlio Antônio Pereira Araújo, Karina Carvalho Salmazi, Esper Georges Kállas, Luis Eduardo Coelho Andrade
Publikováno v:
Revista Brasileira de Reumatologia, Vol 48, Iss 6, Pp 342-355 (2008)
O sistema imune sadio deve manter o balanço entre a capacidade de responder a agentes infecciosos e de sustentar a autotolerância. A ausência de resposta adequada submete o indivíduo aos efeitos deletérios da invasão por patógenos, ao passo qu
Externí odkaz:
https://doaj.org/article/0c1fec531ad94066ada2cd08e64282f7
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Maternal-fetal immune-tolerance occurs throughout the whole gestational trimester, thus a mother can accept a genetically distinct fetus without immunological aggressive behavior. HLA-G, one of the non-classical HLA class I molecules, is restricted-e
Autor:
LM Massis, S Ruddle, SM Brewer, R Schade, R Narasimhan, JD Honeycutt, THM Pham, JA McKenna, SW Brubaker, P Chairatana, JA Klein, M Margalef-Català, MR Amieva, JG Vilches-Moure, DM Monack
Superspreader hosts carry out most pathogen transmission events and are often disease tolerant since they remain asymptomatic despite high pathogen burdens. Here we describe the superspreader immune state that allows for disease tolerance. In a model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be597c7617ec9bf9726b296d028a5971
https://doi.org/10.1101/2021.07.16.452606
https://doi.org/10.1101/2021.07.16.452606