Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Immunologic/pharmacology"'
Autor:
Vandebriel, Rob J., Stalpers, Coen A.L., Vermeulen, Jolanda P., Remkes, Mariska, Schmelter, Marit, Broere, Femke, Hoefnagel, Marcel H.N.
Publikováno v:
Vaccine
Safety and potency assessment for batch release testing of established vaccines still relies partly on animal tests. An important avenue to move to batch release without animal testing is the consistency approach. This approach is based on thorough c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d7df5b10786c856cf518b8b471e363f
https://doi.org/10.1016/j.vaccine.2022.08.022
https://doi.org/10.1016/j.vaccine.2022.08.022
Autor:
Martinez Sanz, Paula, van Rees, Dieke J, van Zogchel, Lieke M J, Klein, Bart, Bouti, Panagiota, Olsman, Hugo, Schornagel, Karin, Kok, Ivana, Sunak, Ali, Leeuwenburg, Kira, Timmerman, Ilse, Dierselhuis, Miranda P, Kholosy, Waleed M, Molenaar, Jan J, van Bruggen, Robin, van den Berg, Timo K, Kuijpers, Taco W, Matlung, Hanke L, Tytgat, Godelieve A M, Franke, Katka, Afd Pharmaceutics, Pharmaceutics
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Journal for ImmunoTherapy of Cancer, 9(5), 1. BioMed Central Ltd.
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, 9(5), 1. BioMed Central
Journal for immunotherapy of cancer, 9(5):e002259. BioMed Central Ltd.
Journal for ImmunoTherapy of Cancer, 9(5), 1. BioMed Central Ltd.
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, 9(5), 1. BioMed Central
Journal for immunotherapy of cancer, 9(5):e002259. BioMed Central Ltd.
BackgroundCurrent immunotherapy for patients with high-risk neuroblastoma involves the therapeutic antibody dinutuximab that targets GD2, a ganglioside expressed on the majority of neuroblastoma tumors. Opsonized tumor cells are killed through antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a8c22e38a8b458ee9e9cfac080fa47
https://doi.org/10.1136/jitc-2020-002259
https://doi.org/10.1136/jitc-2020-002259
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-7 (2018)
Malaria Journal
Malaria journal, vol. 17, no. 1, pp. 77
Malaria Journal
Malaria journal, vol. 17, no. 1, pp. 77
Background Plasmodium parasites are known to impose fitness costs on their vertebrate hosts. Some of these costs are due to the activation of the immune response, which may divert resources away from self-maintenance. Plasmodium parasites may also im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0534c0c46fb8de35f0ac6627b8b1cd3c
http://link.springer.com/article/10.1186/s12936-018-2219-3
http://link.springer.com/article/10.1186/s12936-018-2219-3
Autor:
Steven W. Wingett, Kassim Kamaka, Danika L. Hill, Martin S. Zand, Jiong Wang, Elizabeth F. Wallin, Catherine Mkindi, François Spertini, Wim Pierson, Régine Audran, Daniel J. Bolland, Said Jongo, Sophie Houard, Michelle A. Linterman, Anne E. Corcoran, Edward J. Carr, Claudia Daubenberger
Publikováno v:
The Journal of experimental medicine, vol. 216, no. 8, pp. 1857-1873
The Journal of Experimental Medicine
The Journal of Experimental Medicine
A rational strategy to achieve optimal vaccine responses is to potentiate Tfh cells and the germinal center response. This work shows the adjuvant GLA-SE enhances circulating Tfh cells and enduring antibody responses to a malaria vaccine in Tanzanian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02643e911e2eb9a88542a1b440cd038
https://serval.unil.ch/notice/serval:BIB_B9B6A1FE4844
https://serval.unil.ch/notice/serval:BIB_B9B6A1FE4844
Autor:
Claire-Anne Siegrist, Paul-Henri Lambert, Flora Castellino, Floriane Auderset, Anja Seubert, Beatris Mastelic Gavillet, Giuseppe Del Giudice, John S. Tregoning, Ennio De Gregorio, Christiane S. Eberhardt
Publikováno v:
J Immunol
Journal of Immunology, Vol. 194, No 10 (2015) pp. 4836-4845
Journal of Immunology, Vol. 194, No 10 (2015) pp. 4836-4845
The early life influenza disease burden calls for more effective vaccines to protect this vulnerable population. Influenza vaccines including the MF59 oil-in-water adjuvant induce higher, broader, and more persistent Ab responses in adults and partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abca0938f0b186e151fbb5a3aa2fd758
https://doi.org/10.4049/jimmunol.1402071
https://doi.org/10.4049/jimmunol.1402071
Publikováno v:
Scientific Reports
Scientific reports, vol. 7, pp. 43844
Scientific reports, vol. 7, pp. 43844
The inflammasome–IL-1 axis and type I interferons (IFNs) have been shown to exert protective effects upon respiratory tract infections. Conversely, IL-1 has also been implicated in inflammatory airway pathologies such as asthma and chronic obstruct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db7b72299d640486f2d0ab0a279b556
Autor:
Martin Schreder, Arnold Bolomsky, Niklas Zojer, Tobias Meißner, Heinz Ludwig, Dirk Hose, Sabine Pfeifer
Publikováno v:
Experimental Hematology. 42:516-525
Osteoblastic activity is severely impaired in active myeloma, contributing to the development of myeloma bone disease. Although several drugs reducing osteoclast-mediated bone degradation are in clinical use, approaches to specifically augment bone f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadc383af9285f518a1bbf0536cd2e44
https://doi.org/10.1016/j.exphem.2014.03.005
https://doi.org/10.1016/j.exphem.2014.03.005
Publikováno v:
Methods in molecular biology, vol. 1494, pp. 73-86
QS-21, a saponin extracted from the tree Quillaja saponaria Molina, is a vaccine adjuvant which has been shown to elicit robust antibody and cell-mediated immune responses in a variety of preclinical and clinical studies [1]. Its purification from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::efa4a661b1da4c154befe403e0d016db
https://serval.unil.ch/notice/serval:BIB_AF425E56083A
https://serval.unil.ch/notice/serval:BIB_AF425E56083A
Autor:
Marta Ruiz, Marta Martínez, Maika Durantez, Pablo Sarobe, Jaione Bezunartea, Francisco Borrás-Cuesta, Juan José Lasarte, Cristina Mansilla, Fernando Aranda, Jose I Riezu-Boj, Diana Llopiz, Jesús Prieto, Nancy Díaz-Valdés
Publikováno v:
Cancer Research. 71:3214-3224
Low antigen expression and an absence of coimmunostimulatory signals may be partly responsible for the low immunogenicity of many tumors. It may be possible to overcome this situation by defining a combination of adjuvants and antigens that can activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf3d3c8a704aaf06d77cdbf34b3b91e
https://doi.org/10.1158/0008-5472.can-10-3259
https://doi.org/10.1158/0008-5472.can-10-3259
Autor:
Shozo Izui, R. Michael E. Parkhouse, Thomas Moll, Yves Chicheportiche, Isabelle Semac, Lars Nitschke, Frédéric Lajaunias, Eduardo Martinez-Soria
Publikováno v:
Journal of Immunology, Vol. 168, No 12 (2002) pp. 6078-6083
Scopus-Elsevier
CIÊNCIAVITAE
Scopus-Elsevier
CIÊNCIAVITAE
CD22 is a B cell-restricted transmembrane protein that apparently controls signal transduction thresholds initiated through the B cell Ag receptor (BCR) in response to Ag. However, it is still poorly understood how the expression of CD22 is regulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33ec62626860cdc3e0f48868372dc40
https://doi.org/10.4049/jimmunol.168.12.6078
https://doi.org/10.4049/jimmunol.168.12.6078