Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Immunoglobulin heavy locus"'
Autor:
Abdelrahman Nanah, Samer Al Hadidi
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:e213-e219
Bing-Neel syndrome (BNS) is a rare syndrome that occurs in patients with Waldenstrom macroglobulinemia and is characterized by lymphoplasmacytic infiltration into the leptomeningeal tissue and/or the central nervous system. It represents an extramedu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245fb21d7b8291c6c823743f46279159
https://doi.org/10.1016/j.clml.2021.09.014
https://doi.org/10.1016/j.clml.2021.09.014
Autor:
Cody Ashby, Brian A Walker, Marco Trevisan-Herraz, Sharmilan Thanendrarajan, Kent Fung, Agata Cieslak, Shmuel Yaccoby, Maurizio Zangari, Aneta Mikulasova, Daniel Rico, Vahid Asnafi, Lisa J. Russell, Nefeli Karataraki, Anne E. Corcoran, Daniel Kent, Sophie Hambleton, Carolina Schinke, Gareth J. Morgan, Salvatore Spicuglia, Frits van Rhee, Chris A. Brackley
Publikováno v:
Mikulasova, A, Kent, D, Trevisan-Herraz, M, Karataraki, N, Fung, K T M, Ashby, C, Cieslak, A, Yaccoby, S, van Rhee, F, Zangari, M, Thanendrarajan, S, Schinke, C, Morgan, G J, Asnafi, V, Spicuglia, S, Brackley, C A, Corcoran, A E, Hambleton, S, Walker, B A, Rico, D & Russell, L J 2021, ' Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers ', Genome Research, vol. 2022, 32, pp. 1343-1354 . https://doi.org/10.1101/gr.276042.121
Chromosomal translocations are important drivers of haematological malignancies whereby proto-oncogenes are activated by juxtaposition with enhancers, often called enhancer hijacking. We analysed the epigenomic consequences of rearrangements between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eedf4484dfbaf56189657b0745b5f853
https://doi.org/10.1101/gr.276042.121
https://doi.org/10.1101/gr.276042.121
Autor:
Emina Jukic, Johannes Zschocke, Irmgard Verdorfer, Eberhard Gunsilius, Friedrich Fresser, Roman Weger, David Nachbaur, Günther Gastl, Normann Steiner, Dominik Wolf, Michael Steurer, Wolfgang Willenbacher, Ewald Wöll, Markus A. Keller, Carmen Ruepp, Maurus Locher
Publikováno v:
American Journal of Hematology
Hyperdiploidy (HRD) and specific immunoglobulin heavy locus (IGH) translocations are primary chromosomal abnormalities (CA) in multiple myeloma (MM). In this retrospective study of 794 MM patients we aimed to investigate clinical features and common
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d945ebf8d0f8de0d5656315b6b690e5d
https://pubmed.ncbi.nlm.nih.gov/32936982
https://pubmed.ncbi.nlm.nih.gov/32936982
Autor:
Kah Keng Wong, Venugopal Balakrishnan, Shandra Devi Balasubramaniam, Gurjeet Kaur, Chern Ein Oon
Publikováno v:
Life Sciences. 256:118026
Aim We aimed to determine the biological processes and pathways involved in cervical carcinogenesis associated with high-risk human papillomavirus (HPV) infection. Materials and methods Total RNA was extracted from three formalin-fixed paraffin-embed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ccdbd87a02b2dfc31b18f068adebf3
https://doi.org/10.1016/j.lfs.2020.118026
https://doi.org/10.1016/j.lfs.2020.118026
Autor:
Martina Rincic, Isabel M. Carreira, Jolanta Rygier, Britta Meyer, Thomas Liehr, Beata Grygalewicz, Anna Ejduk, Joana B. Melo, Moneeb A.K. Othman, Barbara Pienkowska-Grela
Publikováno v:
Oncology Letters. 11:2117-2122
Acquired copy number changes are common in acute leukemia. They are reported as recurrent amplifications or deletions (del), and may be indicative of involvement of oncogenes or tumor suppressor genes in acquired disease, as well as serving as potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e200442257235f2c95ca3a505961360
https://doi.org/10.3892/ol.2016.4169
https://doi.org/10.3892/ol.2016.4169
Autor:
Xuan Zhou, Rui Cao, Yuling Li, Jixian Huang, Lin Li, Xiaoli Liu, Ziyuan Lu, Jing Sun, Qifa Liu, Qingfeng Du, Huan Li, Qisi Lu, Na Xu
Publikováno v:
Journal of Cancer
Deletion of cyclin-dependent kinase inhibitor 2A/B (CDKN2A/B) is well known in many hematologic malignancies, but only few reports have investigated this deletion effect on clinical prognosis. This study performed analysis of the CDKN2 deletion in 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6d882e69c8271c18e2e9572f8f79a5
http://europepmc.org/articles/PMC4615347
http://europepmc.org/articles/PMC4615347
Autor:
Jacob Rozmus, Klaus Warnatz, Polina Stepensky, Andrew L. Snow, Stuart E. Turvey, Raif S. Geha, Johann Greil, Jürgen Ruland, Alain Fischer, Andreas Gewies, Bärbel Keller, Bénédicte Neven, Anne Durandy, Thomas Giese, Margaret L. McKinnon, Shan-Yu Fung
Publikováno v:
Journal of Allergy and Clinical Immunology
Next-generation DNA sequencing has accelerated the genetic characterization of many human primary immunodeficiency diseases (PIDs). These discoveries can be lifesaving for the affected patients and also provide a unique opportunity to study the effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad495c041cf14f8d82e1cce991d69211
https://doi.org/10.1016/j.jaci.2014.06.015
https://doi.org/10.1016/j.jaci.2014.06.015
Autor:
Wei Cui, Katsuya Miyatani, Hiroshi Sonobe, Nobuharu Fujii, Tadashi Yoshino, Noriko Iwaki, Rie Yamasaki, Yasuharu Sato, Ichiro Yamadori, Yoshinobu Maeda, Naoya Nakamura, Katsuyoshi Takata, Tomoko Miyata-Takata, Katsuhiko Saito, Kayoko Iwatani, Seiko Sawada-Kitamura, Mitsune Tanimoto, Maiko Tamura, Yasushi Terasaki
Publikováno v:
Human Pathology. 45:1379-1387
Cases of low-grade B-cell lymphoma presenting primarily in the bone marrow are rare, and its clinicopathology remains unclear. We retrospectively examined patients with low-grade B-cell lymphoma presenting primarily in the bone marrow. Fourteen patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70931783d1276fc7137c2015511fe0dc
https://doi.org/10.1016/j.humpath.2014.02.010
https://doi.org/10.1016/j.humpath.2014.02.010
Autor:
Cosimo Cumbo, Paola Orsini, Crescenzio Francesco Minervini, Elisa Parciante, Giorgina Specchia, Angelo Cellamare, Claudia Brunetti, Antonella Zagaria, Anna Mestice, Luciana Impera, Luisa Anelli, Angela Minervini, Giuseppina Tota, Nicoletta Coccaro, Francesco Albano, Paola Casieri
Primary plasma cell leukemia (pPCL) is an uncommon form of plasma cell dyscrasia, and the most aggressive of the human monoclonal gammopathies. The t(11;14)(q13;q32) rearrangement is the most common alteration in pPCL, promoting cyclin D1 (CCND1) gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b300abe7216c4c3a2f2b5300a31af1
https://europepmc.org/articles/PMC4950221/
https://europepmc.org/articles/PMC4950221/
Autor:
Hironobu Minami, Hiroshi Matsuoka, Atsuo Okamura, Tohru Murayama, Katsuya Yamamoto, Yumiko Inui, Kimikazu Yakushijin
Publikováno v:
Leukemia Research. 36:e202-e205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5fe971b22dee21b804d818944733808
https://doi.org/10.1016/j.leukres.2012.05.002
https://doi.org/10.1016/j.leukres.2012.05.002