Structural insight to elucidate the binding specificity of the anti-cortisol Fab fragment with glucocorticoids

Autor: Veikko Eronen, Antti Tullila, Kristiina Iljin, Juha Rouvinen, Tarja K. Nevanen, Nina Hakulinen

Publikováno v: Eronen, V, Tullila, A, Iljin, K, Rouvinen, J, Nevanen, T K & Hakulinen, N 2023, ' Structural insight to elucidate the binding specificity of the anti-cortisol Fab fragment with glucocorticoids ', Journal of Structural Biology, vol. 215, no. 2, 107966 . https://doi.org/10.1016/j.jsb.2023.107966

Cortisol is a steroid hormone that is produced by the adrenal gland. It is a primary stress hormone that increases glucose levels in the blood stream. High concentrations of cortisol in the body can be used as a biomarker for acute and chronic stress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5308381e7ae11aea0e1554ad31f31abb
https://cris.vtt.fi/en/publications/06e4ad63-7650-458e-a656-421f311cea9d

Quantifying histone and RNA polymerase II post-translational modification dynamics in mother and daughter cells

Autor: Timothy J. Stasevich, Hiroshi Kimura, Yuko Sato, Naohito Nozaki

Publikováno v: Methods (San Diego, Calif.). 70:77-88

Post-translational histone modifications are highly correlated with transcriptional activity, but the relative timing of these marks and their dynamic interplay during gene regulation remains controversial. To shed light on this problem and clarify t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b8b216adb1278f785d52a65ea1b882
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100714246