Identification of a superagonist variant of the immunodominant Yellow fever virus epitope NS4b214-222 by combinatorial peptide library screening

Autor: Amandine Bovay, Vincent Zoete, Daniel E. Speiser, Philippe Delbreil, Pierre J. Rizkallah, David K. Cole, Konrad Beck, Silvia A. Fuertes Marraco

Publikováno v: Molecular immunology, vol. 125, pp. 43-50

The CD8 T cell response to the HLA-A2-restricted epitope LLWNGPMAV (LLW) of the non-structural protein 4b of Yellow Fever Virus (YFV) is remarkably immunodominant, highly prevalent and powerful in YFV-vaccinated humans. Here we used a combinatorial p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdebc85543c1a1115afc50e5311e006
https://orca.cardiff.ac.uk/id/eprint/133295/1/Mol_Immunol_060720.pdf

Conformational epitopes of myelin oligodendrocyte glycoprotein are targets of potentially pathogenic antibody responses in multiple sclerosis

Autor: H.-Christian von Büdingen, Til Menge, Claude P. Genain, Patrice H. Lalive

Publikováno v: Journal of Neuroinflammation, Vol 8, Iss 1, p 161 (2011)
Journal of neuroinflammation
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol. 8 (2011) P. 161
Menge, Til; Lalive, Patrice H; von Büdingen, H-Christian; & Genain, Claude P. (2011). Conformational epitopes of myelin oligodendrocyte glycoprotein are targets of potentially pathogenic antibody responses in multiple sclerosis. Journal of Neuroinflammation, 8(1), 161. doi: http://dx.doi.org/10.1186/1742-2094-8-161. Retrieved from: http://www.escholarship.org/uc/item/931532mb

Background Myelin/oligodendrocyte glycoprotein (MOG) is a putative autoantigen in multiple sclerosis (MS). Establishing the pathological relevance and validity of anti-MOG antibodies as biomarkers has yielded conflicting reports mainly due to differe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e17e6b96a1abdde098c3038baff89c
http://www.jneuroinflammation.com/content/8/1/161

Rapid and long-term disappearance of CD4+ T lymphocyte responses specific for Anaplasma marginale major surface protein-2 (MSP2) in MSP2 vaccinates following challenge with live A. marginale

Autor: Abbott, Jeffrey R, Palmer, Guy H, Kegerreis, Kimberly A, Hetrick, Peter F, Howard, Chris J, Hope, Jayne, Brown, Wendy C

Publikováno v: Abbott, J R, Palmer, G H, Kegerreis, K A, Hetrick, P F, Howard, C J, Hope, J & Brown, W C 2005, ' Rapid and long-term disappearance of CD4+ T lymphocyte responses specific for Anaplasma marginale major surface protein-2 (MSP2) in MSP2 vaccinates following challenge with live A. marginale ', Journal of Immunology, vol. 174, no. 11, pp. 6702-15 .

In humans and ruminants infected with Anaplasma, the major surface protein 2 (MSP2) is immunodominant. Numerous CD4(+) T cell epitopes in the hypervariable and conserved regions of MSP2 contribute to this immunodominance. Antigenic variation in MSP2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::4e7fe7a446f8b3dc3f9b39b047ce66ec
https://hdl.handle.net/20.500.11820/cdaef7fa-ec99-4e88-9384-20f7b6ff273a

P0 glycoprotein peptides 56-71 and 180-199 dose-dependently induce acute and chronic experimental autoimmune neuritis in Lewis rats associated with epitope spreading

Autor: Peter H. van der Meide, Sigliti-Henrietta Pelidou, Michael Levi, Jie Zhu, Eilhard Mix, Bengt Winblad, Georgia Deretzi, Li-Ping Zou

Publikováno v: Journal of neuroimmunology. 114(1-2)

Two synthetic peripheral nerve myelin P0 protein peptides, an immunodominant (amino acids 180-199) and a cryptic (amino acids 56-71) one, induced an acute or chronic course of experimental autoimmune neuritis (EAN) in Lewis rats, when given at low do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d3cb9c73917feb3a75a52268dee124
https://pubmed.ncbi.nlm.nih.gov/11240020