Výsledky vyhledávání - "Immunocompromised Mice"

Akademický článek

Recombinant chimeric horsepox virus (TNX-801) is attenuated relative to vaccinia virus strains in both in vitro and in vivo models

Autor: Stephanie V. Trefry, Mayanka Awasthi, Christy N. Raney, Amy L. Cregger, Chase A. Gonzales, Brittney L. Layton, Robert N. Enamorado, Nelson A. Martinez, Deborah S. Gohegan, Masoudeh Masoud-Bahnamiri, Jennifer Y. Cho, Dawn M. Myscofski, Tinoush Moulaei, Natasza E. Ziółkowska, Scott J. Goebel, Seth Lederman, Sina Bavari, Farooq Nasar

Publikováno v: mSphere, Vol 9, Iss 12 (2024)

ABSTRACT Recombinant chimeric horsepox virus (TNX-801) is a preclinical vaccine in development against mpox and smallpox. In this report, we investigated the potential phenotypic differences in in vitro and in vivo models between TNX-801 and older va

Externí odkaz: https://doaj.org/article/7144c18377e74ad4a34bf65844c292b2

Zobrazit plný text záznamu

Akademický článek

Comparative development of human filariae Loa loa, Onchocerca volvulus and Mansonella perstans in immunocompromised mouse strains

Autor: Valerine C. Chunda, Fanny Fri Fombad, Chi Anizette Kien, Rene Ebai, Frederick Esofi, Anna Ning Ntuh, Emmanuel Ouam, Narcisse Victor Tchamatchoua Gandjui, Relindis Ekanya, Franck Nietcho, Lucy Cho Nchang, Chefor Magha, Abdel Jelil Njouendou, Peter Enyong, Achim Hoerauf, Samuel Wanji, Manuel Ritter

Publikováno v: Frontiers in Tropical Diseases, Vol 5 (2024)

IntroductionMouse models of human filarial infections are not only urgently needed to investigate the biology of the nematodes and their modulation of the host’s immunity, but will also provide a platform to screen and test novel anti-filarial drug

Externí odkaz: https://doaj.org/article/d2066627f88a44eca8ac60bfc4366a77

Zobrazit plný text záznamu

Akademický článek

Animal model considerations for chordoma research: reproducing the tumor microenvironment in vivo with humanized mice

Autor: Beatrice Campilan, Christian Schroeder, Emilija Sagaityte, Jonathan Arditi, Owen P. Leary, Ziya L. Gokaslan, Patricia L. Zadnik Sullivan, Margot Martinez-Moreno

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

Animal models have been commonly used in immunotherapy research to study the cell response to external agents and to assess the effectiveness and safety of new therapies. Over the past few decades, immunocompromised (also called immunodeficient) mice

Externí odkaz: https://doaj.org/article/4a2e36a1f4474a9285ec7900e49794d0

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Annona muricata Leaf as an Anti-Cryptosporidial Agent: An In Silico Molecular Docking Analysis and In Vivo Studies

Autor: Eman S. El-Wakil, Hagar F. Abdelmaksoud, Majed H. Wakid, Muslimah N. Alsulami, Olfat Hammam, Haleema H. Albohiri, Marwa M. I. Ghallab

Publikováno v: Pharmaceuticals, Vol 16, Iss 6, p 878 (2023)

Cryptosporidiosis is a serious parasitic diarrheal disease linked to the occurrence of colorectal cancer in immunocompromised patients. The FDA-approved drug nitazoxanide (NTZ) achieved a temporary effect, and relapses occur. Annona muricata leaf is

Externí odkaz: https://doaj.org/article/87f15a6fd7044781b0dd6f3962ca2736

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Immunomodulatory effect of Cyclocarya paliurus polysaccharide in cyclophosphamide induced immunocompromised mice

Autor: Xiong, Lei ^{a, 1}, Ouyang, Ke-Hui ^{b, 1}, Chen, Hui ^a, Yang, Zhan-Wei ^a, Hu, Wen-Bing ^a, Wang, Ning ^a, Liu, Xin ^a, Wang, Wen-Jun ^{a, ∗}

Publikováno v: In Bioactive Carbohydrates and Dietary Fibre October 2020 24

Zobrazit plný text záznamu

Akademický článek

C57BL/6J Mice Are Not Suitable for Modeling Severe SARS-CoV-2 Beta and Gamma Variant Infection

Autor: Joshua M. Currey, Felix Rabito, Nicholas J. Maness, Robert V. Blair, Jay Rappaport, Xuebin Qin, Jay K. Kolls, Akhilesh K. Srivastava

Publikováno v: Viruses, Vol 14, Iss 5, p 966 (2022)

SARS-CoV-2 variants, including B.1.1.7 (Alpha), B.1.351 (Beta), P.1 (Gamma), and B.1.617.2 (Delta) variants, have displayed increased transmissibility and, therefore, have been categorized as variants of concern (VOCs). The pervasiveness of VOCs sugg

Externí odkaz: https://doaj.org/article/811a0ef383a9462dacaa3476e3de2b76

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Virucidal and Immunostimulating Activities of Monogalactosyl Diacylglyceride from Coccomyxa sp. KJ, a Green Microalga, against Murine Norovirus and Feline Calicivirus

Autor: Kyoko Hayashi, Satoko Komatsu, Hitoshi Kuno, Satomi Asai, Iori Matsuura, Vyankatesh Ramlu Kudkyal, Toshio Kawahara

Publikováno v: Marine Drugs, Vol 20, Iss 2, p 131 (2022)

Human noroviruses are the most common pathogens causing acute gastroenteritis and may lead to more severe illnesses among immunosuppressed people, including elderly and organ transplant recipients. To date, there are no safe and effective vaccines or

Externí odkaz: https://doaj.org/article/77662929e8dd457faec6d0faffcacb02

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Vyhledávací nástroje:

Upřesnit hledání