Zobrazeno 1 - 10
of 7 397
pro vyhledávání: '"Immune suppression"'
Autor:
Milan Kuchař, Kristýna Sloupenská, Leona Rašková Kafková, Yaroslava Groza, Jozef Škarda, Petr Kosztyu, Marie Hlavničková, Joanna M. Mierzwicka, Radim Osička, Hana Petroková, Stephen I. Walimbwa, Shiv Bharadwaj, Jiří Černý, Milan Raška, Petr Malý
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Human interleukin-22 (IL-22) is known as a “dual function” cytokine that acts as a master regulator to maintain homeostasis, structural integrity of the intestinal epithelial barrier, and shielding against bacterial pathogens.
Externí odkaz:
https://doaj.org/article/7572fe8ba3d04303a546ae87cac08392
Autor:
Chihiro Kawai, Masashi Miyao, Hirokazu Kotani, Hirozo Minami, Hitoshi Abiru, Keiji Tamaki, Yoko Nishitani
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Traumatic brain injury (TBI) has been found to be associated with certain peripheral organ injuries; however, a few studies have explored the chronological influences of TBI on multiple organs and the systemic effects of therapeutic interven
Externí odkaz:
https://doaj.org/article/5a4c530b40274b9fb325990ac4fd5cd1
Autor:
Fusheng Zhang, Yongsu Ma, Dongqi Li, Jianlei Wei, Kai Chen, Enkui Zhang, Guangnian Liu, Xiangyu Chu, Xinxin Liu, Weikang Liu, Xiaodong Tian, Yinmo Yang
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-32 (2024)
Abstract Metabolic reprogramming provides tumors with an energy source and biofuel to support their survival in the malignant microenvironment. Extensive research into the intrinsic oncogenic mechanisms of the tumor microenvironment (TME) has establi
Externí odkaz:
https://doaj.org/article/39bb2397a0014455aa69c3ece416888d
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background Multiple sclerosis (MS) therapeutic goals have traditionally been dichotomized into two distinct avenues: immune-modulatory-centric interventions and pro-regenerative strategies. Oligodendrocyte progenitor cells (OPCs) were regard
Externí odkaz:
https://doaj.org/article/f3b0a8dabcaa40e0a58c3f1e48382179
Publikováno v:
Journal of Hepatocellular Carcinoma, Vol Volume 11, Pp 1171-1183 (2024)
Yi-Ning Du,1 Jin-Wei Zhao2 1Department of Medical Sciences, Li Ka-shing School of Medicine, University of Hong Kong, Hong Kong, People’s Republic of China; 2Department of Hepatopancreatobiliary Surgery, Second Hospital of Jilin University, Jilin Un
Externí odkaz:
https://doaj.org/article/b422433d42a448848e1f9120d53a2bbe
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-34 (2024)
Abstract Extracellular vesicles (EVs) are lipid bilayer structures released by all cells and widely distributed in all biological fluids. EVs are implicated in diverse physiopathological processes by orchestrating cell–cell communication. Colorecta
Externí odkaz:
https://doaj.org/article/2b381077eb514a63afcbf4c59d362a2e
Autor:
Longsheng Wang, Jie Zhang, Wenxin Zhang, Mingming Zheng, Hongjie Guo, Xiaohui Pan, Wen Li, Bo Yang, Ling Ding
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 5, Pp 1951-1964 (2024)
Adenosine (Ado) is significantly elevated in the tumor microenvironment (TME) compared to normal tissues. It binds to adenosine receptors (AdoRs), suppressing tumor antigen presentation and immune cell activation, thereby inhibiting tumor adaptive im
Externí odkaz:
https://doaj.org/article/47c85988398546b29c2f6ccb59e34f4c
Autor:
Yan-Lin Tao, Jing-Ran Wang, Miao Liu, Ya-Nan Liu, Jin-Qiu Zhang, Yi-Jing Zhou, Shao-wei Li, Shu-Fen Zhu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Sepsis, a disease with high incidence, mortality, and treatment costs, has a complex interaction with the gut microbiota. With advances in high-throughput sequencing technology, the relationship between sepsis and intestinal dysbiosis has become a ne
Externí odkaz:
https://doaj.org/article/113c78379ba84ae9ac2956ba01b0c41f
Autor:
Hao Zhang, Fangyu Hu, Ouyang Peng, Yihui Huang, Guangli Hu, Usama Ashraf, Meifeng Cen, Xiaojuan Wang, Qiuping Xu, Chuangchao Zou, Yu Wu, Bibo Zhu, Wentao Li, Qunhui Li, Chujun Li, Chunyi Xue, Yongchang Cao
Publikováno v:
Advanced Science, Vol 11, Iss 34, Pp n/a-n/a (2024)
Abstract As a significant infectious disease in livestock, porcine reproductive and respiratory syndrome (PRRS) imposes substantial economic losses on the swine industry. Identification of diagnostic markers and therapeutic targets has been a focal c
Externí odkaz:
https://doaj.org/article/ee38c485bd984957962a88528543baff