Zobrazeno 1 - 10
of 542
pro vyhledávání: '"Immune signature"'
Autor:
Zhengrui Huang, Lu Sun, Yudie Gao, Meiting Shi, Ping Zhang, Yuzhen Ding, Jian Wang, Jiachun Wei, Xiuli Yang, Ruiman Li
Publikováno v:
BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Preeclampsia is a severe obstetric disorder that significantly affects the maternal and neonatal peri-partum safety and long-term quality of life. However, there is limited research exploring the common mechanisms and potential cl
Externí odkaz:
https://doaj.org/article/efba06b2d87d43a8b719ecba9ece29c5
Publikováno v:
AIMS Bioengineering, Vol 10, Iss 4, Pp 440-465 (2023)
Background: Myelodysplastic syndrome is a malignant clonal disorder of hematopoietic stem cells (HSC) with both myelodysplastic problems and hematopoietic disorders. The greatest risk factor for the development of MDS is advanced age, and aging caus
Externí odkaz:
https://doaj.org/article/a20716992bdd449e8157a9ad92452059
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPulmonary infections are a crucial health concern for patients with advanced non–small-cell lung cancer (NSCLC). Whether the clinical outcome of pulmonary infection is influenced by immunotherapy(IO) remains unclear. By evaluating immune
Externí odkaz:
https://doaj.org/article/e47016c1e7a845a4945899bdc26960c0
Autor:
Yizhe Mao, Tuba N. Gide, Nurudeen A. Adegoke, Camelia Quek, Nigel Maher, Alison Potter, Ellis Patrick, Robyn P. M. Saw, John F. Thompson, Andrew J. Spillane, Kerwin F. Shannon, Matteo S. Carlino, Serigne N. Lo, Alexander M. Menzies, Inês Pires da Silva, Georgina V. Long, Richard A. Scolyer, James S. Wilmott
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Gene expression profiling is increasingly being utilised as a diagnostic, prognostic and predictive tool for managing cancer patients. Single-sample scoring approach has been developed to alleviate instability of signature scores
Externí odkaz:
https://doaj.org/article/ef7110af153c44aabefb4fbcf176e3ad
Autor:
Lijuan Li, Nan Wu, Gaojian Zhuang, Lin Geng, Yu Zeng, Xuan Wang, Shuang Wang, Xianhui Ruan, Xiangqian Zheng, Juntian Liu, Ming Gao
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Objective: Due to a lack of effective therapy, triple-negative breast cancer (TNBC) is extremely poor prognosis. Metabolic reprogramming is an important hallmark in tumorigenesis, cancer diagnosis, prognosis, and treatment. Categorizing metabolic pat
Externí odkaz:
https://doaj.org/article/20a69fb3f5be4915b0b5d6a3d5e87f32
Autor:
Long Liu, Xingxing Yu, Zhifeng Li, Xiaohua He, Jie Zha, Zhijuan Lin, Yan Hong, Huijian Zheng, Qian Lai, Kaiyang Ding, Xian Jia, Guo Fu, Haifeng Yu, Haiyan Yang, Zhiming Li, Ken H. Young, Bing Xu
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-6 (2022)
Abstract Background Patients with follicular lymphoma (FL) who experience disease progression within 24 months (POD24) have inferior outcomes. The tumor immune microenvironment (TIME) plays a crucial role in pathogenesis and progression of follicular
Externí odkaz:
https://doaj.org/article/9cd465cfbc6546cc8c5621669bc2d7c4
Publikováno v:
World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background Breast cancer (BC) is a highly heterogeneous disease. Among the BC molecular subtypes, basal-like/triple-negative BC (TNBC) is characterized by a high propensity for relatively early metastases and a lack of available endocrine an
Externí odkaz:
https://doaj.org/article/df2006accd7b4f7d93f5bc2a1d2299b2
Autor:
Yuhui Ma, Hutao Shi, Guangqiang Zhao, Xin Liu, Jingjing Cai, Guangjian Li, Wanlin Chen, Yujie Lei, Lianhua Ye, Chaojiang Fu, Li Zhao, Yongchun Zhou, Yunchao Huang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundChina’s southwestern region, Qujing, harbors a high incidence of non-small cell lung cancer (NSCLC) and related mortality. This study was designed to reveal the impact of an immune-related prognostic signature (IRPS) on advanced NSCLC in
Externí odkaz:
https://doaj.org/article/c8ce58c908534506820a59021c130f46
Autor:
Katharine A Kott, Adam S Chan, Stephen T Vernon, Thomas Hansen, Taiyun Kim, Macha deDreu, Bavani Gunasegaran, Andrew J Murphy, Ellis Patrick, Peter J Psaltis, Stuart M Grieve, Jean Y Yang, Barbara Fazekas de St Groth, Helen M McGuire, Gemma A Figtree
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 11, Pp n/a-n/a (2023)
Abstract Objective The importance of inflammation in atherosclerosis is well accepted, but the role of the adaptive immune system is not yet fully understood. To further explore this, we assessed the circulating immune cell profile of patients with c
Externí odkaz:
https://doaj.org/article/c6896394e4c5467bb8255df0f5093c80
Autor:
Yaël Glasson, Laure-Agnès Chépeaux, Anne-Sophie Dumé, Philippe Jay, Nelly Pirot, Nathalie Bonnefoy, Henri-Alexandre Michaud
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Currently, the study of resistance mechanisms and disease progression in cancer relies on the capacity to analyze tumors as a complex ecosystem of healthy and malignant cells. Therefore, one of the current challenges is to decipher the intra-tumor he
Externí odkaz:
https://doaj.org/article/49ff55de47584104aef0b8187ecdf13a