Zobrazeno 1 - 10
of 698
pro vyhledávání: '"Immune restoration"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/489ddaab83a141d7bd738ea029424e57
Autor:
Yuliana A. Belova, Sergey V. Kotov
Publikováno v:
Consilium Medicum, Vol 26, Iss 2, Pp 88-92 (2024)
Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection with severe brain damage caused by the JC-virus, against the background of immunosuppressive conditions. The diagnosis of PML is complex and includes: the clinical picture
Externí odkaz:
https://doaj.org/article/a74acce1b32f4ca7a771741a6b0f8c22
Autor:
Tao Yang, Zhiman Xie, Zhe Xu, Bo Tu, Huan Lu, Huihuang Huang, Lei Huang, Chao Zhang, Liying Gao, Lei Jin, Ping Ma, Jun Zou, Limin Liu, Cheng Zhen, Chunbao Zhou, Sirun Meng, Yuan-Yuan Li, Jin-Wen Song, Shixiong Yang, Hui-Sheng Ai, Yanmei Jiao, Ming Shi, Ruonan Xu, Fu-Sheng Wang
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Recurrent opportunistic infections (OIs) in patients with severely immunosuppressed AIDS remain an unresolved medical challenge despite advancements in antiretroviral therapy (ART). To address this gap, we developed an HLA-mismatched allogeneic adopt
Externí odkaz:
https://doaj.org/article/437226862c2d4cd3907b829d2e65b8c6
Autor:
Wilhelm A. J. W. Vos, Adriana Navas, Elise M. G. Meeder, Marc J. T. Blaauw, Albert L. Groenendijk, Louise E. van Eekeren, Twan Otten, Nadira Vadaq, Vasiliki Matzaraki, Bram van Cranenbroek, Kees Brinkman, Jan van Lunzen, Leo A. B. Joosten, Mihai G. Netea, Willem L. Blok, Andre J. A. M. van der Ven, Hans J. P. M. Koenen, Janneke E. Stalenhoef
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionImmunological non-responders (INR) are people living with HIV (PLHIV) who fail to fully restore CD4+ T-cell counts despite complete viral suppression with antiretroviral therapy (ART). INR are at higher risk for non-HIV related morbidity
Externí odkaz:
https://doaj.org/article/fe9f62a30ced4509bab65036784e5714
Autor:
Yichao Jiang, Xiaoqing Chen, Xinya Ye, Can Wen, Tao Xu, Chao Yu, Wenjing Ning, Guosong Wang, Xinchu Xiang, Xiaomin Liu, Yalin Wang, Yuanzhi Chen, Xue Liu, Changrong Shi, Chao Liu, Quan Yuan, Yixin Chen, Tianying Zhang, Wenxin Luo, Ningshao Xia
Publikováno v:
Advanced Science, Vol 11, Iss 15, Pp n/a-n/a (2024)
Abstract Chronic hepatitis B (CHB) remains a major public health concern because of the inefficiency of currently approved therapies in clearing the hepatitis B surface antigen (HBsAg). Antibody‐based regimens have demonstrated potency regarding vi
Externí odkaz:
https://doaj.org/article/44d6050782c1433d87e077efd94bcad1
Autor:
Hyeon Jin Lee, Ki-Won Shin, Seo Jun Lee, Ji Young Park, In Chul Lee, Hyung-Jun Kwon, Hyung Jae Jeong, Jae-Min Yuk, Young-Bae Ryu, Woo Sik Kim
Publikováno v:
Journal of Functional Foods, Vol 112, Iss , Pp 105981- (2024)
This study investigated the immunological features and therapeutic potential of extracellular vesicle-like nanoparticles isolated from the marine macroalgae Sargassum fusiforme (SF-NPs). SF-NPs were approximately 266.4 nm in size, and comprehensive m
Externí odkaz:
https://doaj.org/article/bf70fdeb4a8246a692161f467da2a401
Autor:
Thomas Daix, Armelle Mathonnet, Scott Brakenridge, Pierre-François Dequin, Jean-Paul Mira, Frederique Berbille, Michel Morre, Robin Jeannet, Teresa Blood, Jacqueline Unsinger, Jane Blood, Andrew Walton, Lyle L. Moldawer, Richard Hotchkiss, Bruno François
Publikováno v:
Annals of Intensive Care, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Background Profound lymphopenia is an independent predictor of adverse clinical outcomes in sepsis. Interleukin-7 (IL-7) is essential for lymphocyte proliferation and survival. A previous phase II study showed that CYT107, a glycosylated rec
Externí odkaz:
https://doaj.org/article/ac01ea5bbb564dde939f73024683bed3
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/962653f714924e558bdb1fdbd63f310d
Autor:
Andrea M. H. Towlerton, Shashidhar Ravishankar, David G. Coffey, Camille E. Puronen, Edus H. Warren
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Long-term antiretroviral therapy (ART) in people living with HIV (PLHIV) is associated with sustained increases in CD4+ T-cell count, but its effect on the peripheral blood T-cell repertoire has not been comprehensively evaluated. In this study, we p
Externí odkaz:
https://doaj.org/article/a9febdcf9fc74b49aee6ef8069050e44
Autor:
Jiaye Liu, Lifeng Wang, Yuying Hou, Yan Zhao, Zhihui Dou, Ye Ma, Dawei Zhang, Yasong Wu, Decai Zhao, Zhongfu Liu, Fujie Zhang, Lei Jin, Ji-Yuan Zhang, Ruonan Xu, Ming Shi, Lei Huang, Zunyou Wu, Mengjie Han, George F. Gao, Fu-Sheng Wang
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 2550-2561 (2020)
ABSTRACTUsing normalization of CD4 counts as the main evaluation parameter of complete immune restoration for HIV-1 patients under antiretroviral therapy (ART) might be not enough. A comprehensive evaluation system more accurately reflecting immune r
Externí odkaz:
https://doaj.org/article/d9b6222a0ad44cf880e43292ebe74e82