Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Immune respons"'
Autor:
Monika Nedomova, Stefanie Haberecht-Müller, Sophie Möller, Simone Venz, Michaela Prochazkova, Jan Prochazka, Frantisek Sedlak, Kallayanee Chawengsaksophak, Elke Hammer, Petr Kasparek, Michael Adamek, Radislav Sedlacek, Jan Konvalinka, Elke Krüger, Klara Grantz Saskova
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110893- (2024)
Summary: DDI2 is an aspartic protease that cleaves polyubiquitinated substrates. Upon proteotoxic stress, DDI2 activates the transcription factor TCF11/NRF1 (NFE2L1), crucial for maintaining proteostasis in mammalian cells, enabling the expression of
Externí odkaz:
https://doaj.org/article/8fa378f6b0684b9892e996b65ed983a4
Akademický článek
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Akademický článek
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Autor:
Bryce M. Warner, Lisa A. Santry, Alexander Leacy, Mable Chan, Phuc H. Pham, Robert Vendramelli, Yanlong Pei, Nikesh Tailor, Emelissa Valcourt, Anders Leung, Shihua He, Bryan D. Griffin, Jonathan Audet, Marnie Willman, Kevin Tierney, Alixandra Albietz, Kathy L. Frost, Jacob G.E. Yates, Robert C. Mould, Lily Chan, Yeganeh Mehrani, Jason P. Knapp, Jessica A. Minott, Logan Banadyga, David Safronetz, Heidi Wood, Stephanie Booth, Pierre P. Major, Byram W. Bridle, Leonardo Susta, Darwyn Kobasa, Sarah K. Wootton
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103219- (2021)
Summary: The pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19). Worldwide efforts are being made to develop vaccines to mitigate this pandemic. We engineered two recombinant Newc
Externí odkaz:
https://doaj.org/article/a9d6cd355eb7470ba0489696155667f5
Autor:
Ang Gao, Zhilin Chen, Assaf Amitai, Julia Doelger, Vamsee Mallajosyula, Emily Sundquist, Florencia Pereyra Segal, Mary Carrington, Mark M. Davis, Hendrik Streeck, Arup K. Chakraborty, Boris Julg
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102311- (2021)
Summary: We describe a physics-based learning model for predicting the immunogenicity of cytotoxic T lymphocyte (CTL) epitopes derived from diverse pathogens including SARS-CoV-2. The model was trained and optimized on the relative immunodominance of
Externí odkaz:
https://doaj.org/article/874d4f9281b64d1cbb85c2625a8ff922
Autor:
Michael Riedelberger, Philipp Penninger, Michael Tscherner, Bernhard Hadriga, Carina Brunnhofer, Sabrina Jenull, Anton Stoiber, Christelle Bourgeois, Andriy Petryshyn, Walter Glaser, Andreas Limbeck, Michael A. Lynes, Gernot Schabbauer, Guenter Weiss, Karl Kuchler
Publikováno v:
iScience, Vol 23, Iss 5, Pp - (2020)
Summary: Host and fungal pathogens compete for metal ion acquisition during infectious processes, but molecular mechanisms remain largely unknown. Here, we show that type I interferons (IFNs-I) dysregulate zinc homeostasis in macrophages, which emplo
Externí odkaz:
https://doaj.org/article/20189ec086c24357bfbc0929fda069b3
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Jonathan Audet, Sarah K. Wootton, Byram W. Bridle, Lily Chan, Lisa A. Santry, Logan Banadyga, Emelissa J. Valcourt, Darwyn Kobasa, Leonardo Susta, Kathy L. Frost, Marnie Willman, Anders Leung, Jessica A. Minott, Robert C. Mould, Nikesh Tailor, Alixandra Albietz, Bryce M. Warner, Jason P. Knapp, Pierre Major, Yanlong Pei, Yeganeh Mehrani, Robert Vendramelli, Phuc H. Pham, Kevin Tierney, Alexander Leacy, Heidi Wood, Jacob G. E. Yates, Mable Chan, David Safronetz, Stephanie A. Booth, Shihua He, Bryan D. Griffin
Publikováno v:
iScience
iScience, Vol 24, Iss 11, Pp 103219-(2021)
iScience, Vol 24, Iss 11, Pp 103219-(2021)
The pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of Coronavirus Disease 2019 (COVID-19). Worldwide efforts are being made to develop vaccines to mitigate this pandemic. We engineered two recombinant Newcastle dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3850159091ded9ae75249b1e3799eb9
https://pubmed.ncbi.nlm.nih.gov/36028140
https://pubmed.ncbi.nlm.nih.gov/36028140
Autor:
Assaf Amitai, Vamsee Mallajosyula, Mary Carrington, Emily Sundquist, Julia Doelger, Boris Julg, Mark M. Davis, Florencia P Segal, Arup K. Chakraborty, Zhilin Chen, Ang Gao, Hendrik Streeck
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 2
Elsevier
iScience, Vol 24, Iss 4, Pp 102311-(2021)
iScience
article-version (status) pre
article-version (number) 2
Elsevier
iScience, Vol 24, Iss 4, Pp 102311-(2021)
iScience
We describe a physics-based learning model for predicting the immunogenicity of Cytotoxic-T-Lymphocyte (CTL) epitopes derived from diverse pathogens including SARS-CoV-2. The model was trained and optimized on the relative immunodominance of CTL epit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb38aead26d4fab8045abf8acaf4a8c
https://pubmed.ncbi.nlm.nih.gov/32511339
https://pubmed.ncbi.nlm.nih.gov/32511339
Autor:
Peter E. Nielsen
Publikováno v:
Mmw Fortschritte Der Medizin
MMW-Fortschritte der Medizin
MMW-Fortschritte der Medizin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f24e6f6b83696c60bfea9e3a4887a6
https://pubmed.ncbi.nlm.nih.gov/32959282
https://pubmed.ncbi.nlm.nih.gov/32959282