Zobrazeno 1 - 10
of 1 510
pro vyhledávání: '"Immune protection"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Toxoplasma gondii (T. gondii) is a zoonotic disease that poses great harm to humans and animals. So far, no effective T. gondii vaccine has been developed to provide fully protection against such parasites. Recently, numerous researches have focused
Externí odkaz:
https://doaj.org/article/a346178b26464030ba7becc870e2b12d
Autor:
Zehui Tong, Xiangting Zhang, Xiao Guo, Gengshan Wu, Shiyang Cao, Yuan Zhang, Xiangze Meng, Tong Wang, Yiqian Wang, Yajun Song, Ruifu Yang, Zongmin Du
Publikováno v:
mSphere, Vol 9, Iss 9 (2024)
ABSTRACT Outer membrane vesicles (OMVs) from Gram-negative bacteria can be used as a vaccine platform to deliver heterologous antigens. Here, the major protective antigens of Yersinia pestis, F1 and LcrV, were fused either with the leader sequence or
Externí odkaz:
https://doaj.org/article/6d44d5a5526849cf95f15b07fe6db233
Autor:
Weiwei Wang, Yu Huang, Yan Zhang, Yuanzheng Qiao, Jun Shi, Jianni Huang, Teng Huang, Tianchao Wei, Meilan Mo, Xiumiao He, Ping Wei
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Novel variant infectious bursal disease virus (nvIBDV) is an emerging genotype (A2dB1b) that can cause severe and prolonged immunosuppression in young chickens. Despite current commercial vaccines being proven to lack complete protection against nvIB
Externí odkaz:
https://doaj.org/article/18225bd2f8eb4c94b88609dee56bee89
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Bioactive molecules in tick saliva are considered to be key to successful feeding and further the transmission of tick-borne pathogens. Problems such as pathogen transmission and animal weight loss result in tick infestation can cause tremen
Externí odkaz:
https://doaj.org/article/d40331079d244ee88e84d27020dd5dab
Attenuated vaccine PmCQ2Δ4555–4580 effectively protects mice against Pasteurella multocida infection
Autor:
Fang He, Pan Xiong, Huihui Zhang, Liu Yang, Yangyang Qiu, Pan Li, Guangfu Zhao, Nengzhang Li, Yuanyi Peng
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-12 (2024)
Abstract Pasteurella multocida type A (PmA) mainly causes respiratory diseases such as pneumonia in bovines, leading to great economic losses to the breeding industry. At present, there is still no effective commercial vaccine against PmA infection.
Externí odkaz:
https://doaj.org/article/2fecf51720cb4b61b153d196e6708c1c
Autor:
Juan Liu, Huafeng Han, Binbin Yang, Naifang Zhang, Jing Li, Xicheng Chen, Jie Wu, Yingying Zhao, Yongsheng Yang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
With the rapid global spread of COVID-19 and the continuous emergence of variants, there is an urgent need to develop safe and effective vaccines. Here, we developed a novel mRNA vaccine, HC009, based on new formulation by the QTsome delivery platfor
Externí odkaz:
https://doaj.org/article/df3d7fd7836f42f6a0614cad492db648
Autor:
Guixin Zhao, Wenlong Duan, Lu Zhang, Wenchao Sun, Wan Liu, Xiaoyu Zhang, Yanying Zhang, Qiumei Shi, Tonglei Wu
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
BackgroundSalmonella enteritidis (S. enteritidis), a zoonotic pathogen with a broad host range, presents a substantial threat to global public health safety. Vaccination stands as an effective strategy for the prevention and control of S. enteritidis
Externí odkaz:
https://doaj.org/article/ca20a99246dd4e93945ddce4393f9a89
Autor:
Wiebke Graf, Franziska Bertram, Katharina Dost, Anna Brennecke, Veronika Kowalski, Victoria van Rüth, Dominik Sebastian Nörz, Birgit Wulff, Benjamin Ondruschka, Klaus Püschel, Susanne Pfefferle, Marc Lütgehetmann, Fabian Heinrich
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
IntroductionHomeless individuals suffer a high burden of vaccine-preventable infectious diseases. Moreover, they are particularly susceptible to adverse infection outcomes with limited access to the health care system. Data on the seroprevalence of m
Externí odkaz:
https://doaj.org/article/30b94de820524a42b15940fee0bbd11e
Autor:
Haoran Zhong, Ling Hou, Fanglin Qin, Yuqi Ren, Bowen Dong, Danlin Zhu, Hao Li, Ke Lu, Zhiqiang Fu, Jinming Liu, Shaopeng Gu, Yamei Jin
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-16 (2023)
Abstract Schistosomiasis is a neglected tropical disease that affects humans and animals in tropical and subtropical regions worldwide. Schistosome eggs are responsible for the pathogenesis and transmission of schistosomiasis, thus reducing egg produ
Externí odkaz:
https://doaj.org/article/4ede3a611170464385f2bfead601d331
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8753 (2024)
Th1 and Th2 cytokines determine the outcome of Leishmania major infection and immune protection depends mainly on memory T cells induced during vaccination. This largely hinges on the nature and type of memory T cells produced. In this study, transge
Externí odkaz:
https://doaj.org/article/36830874125b4487b49dcd283e7134ef