Zobrazeno 1 - 10
of 466
pro vyhledávání: '"Immune environment"'
Autor:
Lu Che, Dengxiong Li, Jie Wang, Zhouting Tuo, Koo Han Yoo, Dechao Feng, Yun Ou, Ruicheng Wu, Wuran Wei
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Evidence suggests that the circadian clock (CIC) is among the important factors for tumorigenesis. We aimed to provide new insights into CIC-mediated molecular subtypes and gene prognostic indexes for prostate cancer (PCa) patient
Externí odkaz:
https://doaj.org/article/5c8eaeef2e6f4af6a413c3ab7bcf747e
Publikováno v:
Experimental Gerontology, Vol 196, Iss , Pp 112584- (2024)
Ischemic stroke (IS) is a severe condition regulated by complex molecular alterations. This study aimed to identify potential nicotinamide adenine dinucleotide (NAD+) metabolism-associated diagnostic markers of IS and explore their associations with
Externí odkaz:
https://doaj.org/article/bc5c2d084741426cbbf8fb8a8bc93ccd
Autor:
Xiaohong Liu, Bo Ren, Yuan Fang, Jie Ren, Xing Wang, Minzhi Gu, Feihan Zhou, Ruiling Xiao, Xiyuan Luo, Lei You, Yupei Zhao
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy with high probability of recurrence and distant metastasis. Liver metastasis is the predominant metastatic mode developed in most pancreatic cancer cases, which seriou
Externí odkaz:
https://doaj.org/article/6dc06b74c056457eab1daeae09e573ad
Autor:
Dong Zhou, Yan‐qi Li, Quan‐xing Liu, Xu‐feng Deng, Liang Chen, Man‐yuan Li, Jiao Zhang, Xiao Lu, Hong Zheng, Ji‐gang Dai
Publikováno v:
Cancer Medicine, Vol 13, Iss 11, Pp n/a-n/a (2024)
Abstract Objective The genomic and molecular ecology involved in the stepwise continuum progression of lung adenocarcinoma (LUAD) from adenocarcinoma in situ (AIS) to minimally invasive adenocarcinoma (MIA) and subsequent invasive adenocarcinoma (IAC
Externí odkaz:
https://doaj.org/article/c1efcca04ca84a6cb828eb67481732c1
Publikováno v:
Experimental Gerontology, Vol 190, Iss , Pp 112415- (2024)
Background: Lymphocyte antigen 96 (LY96) plays an important role in innate immunity and has been reported to be associated with various neurological diseases. However, its role in Parkinson's disease (PD) remains unclear. Methods: Transcriptome data
Externí odkaz:
https://doaj.org/article/d71897c2f1ff4a95bb8bd12ac5abd8df
Autor:
Zixi Chen, Jinpeng Li, Jin Zheng, Fenfen Xiang, Xiaoxiao Li, Mengzhe Zhang, Xiangdong Kang, Rong Wu
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e28451- (2024)
Objective: This research aims to examine the involvement of lymphocyte subsets and inflammatory cytokines in the development and progression of COVID-19. Methods: 164 COVID-19 patients were admitted to hospital between December 2022 and January 2023.
Externí odkaz:
https://doaj.org/article/f85e2e0b70ab4649b56a6a0b5e0aa5dc
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Background: Prostate cancer (PCa) is one of the most common malignancies in men with a poor prognosis. It is therefore of great clinical importance to find reliable prognostic indicators for PCa. Many studies have revealed the pivotal role of protein
Externí odkaz:
https://doaj.org/article/380edee7ac3041ddb7993dfc3e8fe08e
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Increasing evidences have demonstrated that pyroptosis exerts key roles in the occurrence, development of chronic obstructive pulmonary disease. However, the mechanisms of pyroptosis in COPD remain largely unknown. In our research, Statistic
Externí odkaz:
https://doaj.org/article/23a9ad268b144f8d82ea789479707fb7
Autor:
Takanori Teshima, Daigo Hashimoto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Allogeneic hematopoietic cell transplantation (HCT) is a curative therapy for various hematologic malignancies. However, alloimmune response is a double-edged sword that mediates both beneficial graft-versus-leukemia (GVL) effects and harmful graft-v
Externí odkaz:
https://doaj.org/article/32decd913a8c492d907164c187854ab4
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 9005-9023 (2023)
Abstract Lung cancer poses severe threats to human health. It is indispensable to discover more druggable molecular targets. We identified a novel dysregulated long non‐coding RNA (lncRNA), LINC00669, in lung adenocarcinoma (LUAD) by analyzing the
Externí odkaz:
https://doaj.org/article/8f1d776586a542c5b04d17555d6c52dd