Zobrazeno 1 - 10
of 1 106
pro vyhledávání: '"Immune effector"'
Autor:
Chiranjeevi Sainatham, Devvrat Yadav, Aravind Dilli Babu, Jayanth Reddy Tallapalli, Sai Gautham Kanagala, Evgenii Filippov, Franco Murillo Chavez, Nausheen Ahmed, Forat Lutfi
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Immune cell effector therapies, including chimeric antigen receptor (CAR)-T cells, T-cell receptor (TCR) T cells, natural killer (NK) cells, and macrophage-based therapies, represent a transformative approach to cancer treatment, harnessing the immun
Externí odkaz:
https://doaj.org/article/f0abd05f4a5f47ad88dca18090e29d19
Autor:
Min Woo Han, So Yeong Jeong, Chong Hyun Suh, Hyesun Park, Jeffrey P. Guenette, Raymond Y. Huang, Kyung Won Kim, Dok Hyun Yoon
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
ObjectivesWe aim to assess the pooled incidence of immune effector cell-associated neurotoxicity syndrome (ICANS) in clinical trials and real-world studies of chimeric antigen receptor (CAR) T-cell therapy for hematologic malignancy and compare the i
Externí odkaz:
https://doaj.org/article/c9c414da47c743598a43fbd7ba941cb5
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 51, Iss 6, Pp 426-431 (2024)
ObjectiveTo explore the significance of the combined strategy of oncolytic virus infection, immune effector cell supplement, and immune checkpoint blocking in the treatment of gastric cancer. MethodsA tumor-bearing nude mouse model of gastric cancer
Externí odkaz:
https://doaj.org/article/f9618f1a33464605aae3172db47ba2ec
Autor:
Guido Ghilardi, Luca Paruzzo, Vrutti Patel, Jakub Svoboda, Emeline R. Chong, Eugenio Fardella, Elise A. Chong, Giulia Gabrielli, Sunita D. Nasta, Daniel J. Landsburg, Jordan Carter, Raymone Pajarillo, Stefan K. Barta, Griffin White, Elizabeth Weber, Ellen Napier, David L. Porter, Alfred L. Garfall, Stephen J. Schuster, Marco Ruella
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-5 (2024)
Abstract Bendamustine has been retrospectively shown to be an effective and safe lymphodepletion regimen prior to the anti-CD19 chimeric antigen receptor T cell (CART) products tisagenlecleucel and axicabtagene ciloleucel, as well as the anti-BCMA CA
Externí odkaz:
https://doaj.org/article/7841086f48d141fcacd16214fbafb379
Autor:
Yuhan Ma, Hongyuan Zhou, Jiaoli Zhang, Qing Zhang, Yujie Li, Ruiyang Xie, Bingpei Zhang, Ziyuan Shen, Ping Li, Aibin Liang, Keshu Zhou, Lu Han, Yongxian Hu, Kailin Xu, Wei Sang, Xiangmin Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundChimeric antigen receptor T-cell (CAR-T) therapy has offered new opportunities for patients with relapsed/refractory B-cell lymphoblastic leukemia (r/r B-ALL). However, cytokine release syndrome (CRS) and immune effector cell–associated n
Externí odkaz:
https://doaj.org/article/dc38e97ee33a4778844cb1f8c26c8343
Autor:
Corentin Le Cacheux, Audrey Couturier, Clara Sortais, Roch Houot, Morgane Péré, Thomas Gastinne, Amélie Seguin, Jean Reignier, Jean-Baptiste Lascarrou, Jean-Marc Tadié, Quentin Quelven, Emmanuel Canet
Publikováno v:
Annals of Intensive Care, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Background Chimeric antigen receptor T-cell (CAR-T) therapy is increasingly used in patients with refractory haematological malignancies but can induce severe adverse events. We aimed to describe the clinical features and outcomes of patient
Externí odkaz:
https://doaj.org/article/6d5917397a1e41a3b323a60b0ea85ca3
Autor:
Aigul R. Rakhmatullina, Mariya A. Zolotykh, Yuliya V. Filina, Aigul Kh. Valiullina, Ekaterina A. Zmievskaya, Dina U. Gafurbaeva, Aisylu R. Sagdeeva, Emil R. Bulatov, Albert A. Rizvanov, Regina R. Miftakhova
Publikováno v:
Cells, Vol 13, Iss 22, p 1892 (2024)
CAR-T therapy has revolutionized the field of oncology, offering a promising treatment option for cancer patients. However, the significant morbidity associated with therapy-related toxicity presents a major challenge to its widespread use. Despite e
Externí odkaz:
https://doaj.org/article/bbbfc8938c3641e7bc78e8dd68b1a25d
Autor:
Enrico Schalk
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 881-882 (2024)
Externí odkaz:
https://doaj.org/article/ff3396cabde149bd9270f598a3af208a
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Chimeric antigen receptor (CAR) T cell therapies have dramatically improved treatment outcomes for patients with relapsed or refractory B-cell acute lymphoblastic leukemia, large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, and multipl
Externí odkaz:
https://doaj.org/article/00ef79012c4c4dbe9f0470b81faa2a40
Autor:
Marco Aurelio Salvino, Alberto Mussetti, Marta Peña, Annalisa Paviglianiti, Abel Santos Carreira, Daniel Rizky, Anna Sureda
Publikováno v:
Frontiers in Nephrology, Vol 4 (2024)
Cell therapy, specifically the revolutionary chimeric antigen receptor (CAR) T-cell therapy, has transformed the landscape of oncology, making substantial strides in practical treatment approaches. Today, established guidelines for diseases such as l
Externí odkaz:
https://doaj.org/article/f4397de0f82a44eeaeb1a0d77f62d805