Výsledky vyhledávání - "Immune Protection Inducing Protein"

Preliminary Evaluation of the Safety and Immunogenicity of an Antimalarial Vaccine Candidate Modified Peptide (IMPIPS) Mixture in a Murine Model

Autor: Leonardo Roa, Magnolia Vanegas, Catalina Avendaño, Manuel E. Patarroyo, Diana Diaz-Arévalo, Jennifer Lambraño, Manuel A. Patarroyo, Hernando Curtidor

Publikováno v: Repositorio Institucional UDCA
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
instacron:Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Journal of Immunology Research
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
Journal of Immunology Research, Vol 2019 (2019)

Malaria continues being a high-impact disease regarding public health worldwide; the WHO report for malaria in 2018 estimated that ~219 million cases occurred in 2017, mostly caused by the parasite Plasmodium falciparum. The disease cost the lives of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e45a2686b0e4a47db2b970d7441cc8e
https://www.hindawi.com/journals/jir/2019/3832513

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Immune protection-inducing protein structures (IMPIPS) against malaria : The weapons needed for beating Odysseus

Autor: Manuel A. Patarroyo, Hernando Curtidor, Laura Pabón, Luis A. Poloche, Manuel E. Patarroyo

Publikováno v: Homer, (1946) The Odyssey, [Transl. by E.V. Rieu], Penguin Group, London, England
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario

The review covers the functional and structural approach followed by our group for more than 34 years in the search for a methodology that allows the rational design of chemically synthesised vaccines. An analogy between Odysseus, the cunning hero of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d97e1208edc93594725e940bab2162
http://repository.urosario.edu.co/handle/10336/19014

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IMPIPS : The Immune Protection-Inducing Protein Structure concept in the search for steric-electron and topochemical principles for complete fully-protective chemically synthesised vaccine development

Autor: Manuel E. Patarroyo, Manuel A. Patarroyo, Luis A. Poloche, Martha Patricia Alba, Adriana Bermúdez, Magnolia Vanegas, Armando Moreno-Vranich

Publikováno v: Murray, C.J., Rosenfeld, L.C., Lim, S.S., Andrews, K.G., Foreman, K.J., Haring, D., Global malaria mortality between 1980 and 2010: A systematic analysis (2012) Lancet, 379, pp. 413-431., PMID: 22305225
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
PLoS ONE, Vol 10, Iss 4, p e0123249 (2015)
PLoS ONE

Determining immune protection-inducing protein structures (IMPIPS) involves defining the stereo-electron and topochemical characteristics which are essential in MHC-p-TCR complex formation. Modified high activity binding peptides (mHABP) were thus sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322b7c34687ebf873df71deb6a05b905
http://repository.urosario.edu.co/handle/10336/19030

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