Zobrazeno 1 - 10
of 4 568
pro vyhledávání: '"Immune Checkpoints"'
Autor:
Xingcheng Yang, Lijun Jiang, Xiaoying Zhang, Juan Peng, Hu Qian, Lifang Huang, Shaolong He, Zhiqiong Wang, Liting Chen, Yicheng Zhang, Ling Ma, Yuan Chen, Jia Wei
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-5 (2024)
Abstract The role of the compromised immune microenvironment, including immune checkpoints, in myelodysplastic syndromes (MDS) has been identified as critical This study aimed to investigate the expression patterns of immune checkpoints, particularly
Externí odkaz:
https://doaj.org/article/0c0886bf71d24e7fb1a80567baeefd78
Publikováno v:
Molecular Oncology, Vol 18, Iss 10, Pp 2338-2355 (2024)
MYC has been implicated in the pathogenesis of a wide range of human tumors and has been described for many years as a transcription factor that regulates genes with pleiotropic functions to promote tumorigenic growth. However, despite extensive effo
Externí odkaz:
https://doaj.org/article/0db5518ccb4c4c76ba0a8d56e3244828
Autor:
Beibei Li, Rongkai Li
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Background Snail family zinc finger 1 (SNAI1) has been implicated in cancer progression and prognosis across various malignancies. This study aims to elucidate the prognostic significance of SNAI1 expression in Lung Squamous Cell Carcinoma (
Externí odkaz:
https://doaj.org/article/6c9ca778b81743a7abb992c64ab26b8e
Autor:
V. V. Babinsky
Publikováno v:
Acta Biomedica Scientifica, Vol 9, Iss 4, Pp 69-74 (2024)
Background. Autoimmune thyroiditis (AIT) affects more than 5 % of the world’s population.The aim. To determine the level of sPD-1, sPD-L1, sCTLA-4 and sB7.2 molecules in individuals suffering from various forms of autoimmune thyroiditis.Methods. Th
Externí odkaz:
https://doaj.org/article/90dee70109654d96a62e5b50d97dd546
Publikováno v:
Медицинская иммунология, Vol 26, Iss 5, Pp 975-982 (2024)
Changes of the immune state in patients with fibroadenoma (FA) or other benign lesions of the breast, as well as the involvement of immune checkpoints in pathogenesis of these lesions, remain underexplored. The aim of this study was to compare the ex
Externí odkaz:
https://doaj.org/article/52df43d7af1a43aeae381c5203926df5
Autor:
Popa-Navarro Xitlally, Avilés-Salas Alejandro, Hernández-Pedro Norma, Orozco-Morales Mario, Caballé-Pérez Enrique, Castillo-Ruiz Cesar, Lucio-Lozada José, Barrios-Bernal Pedro, Hernandez-Martinez Juan-Manuel, Arrieta Oscar
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background CD155 is a transmembrane protein that inhibits antitumor immune response and represents a predictor of worse prognosis in non-small-cell lung cancer (NSCLC). However, it remains unexplored its association with clinical characteris
Externí odkaz:
https://doaj.org/article/1ebedd5e333e4f3c914155199daf9952
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 7239-7257 (2024)
Photodynamic therapy (PDT) can not only directly eliminate cancer cells, but can also stimulate antitumor immune responses. It also affects the expression of immune checkpoints. The purpose of this review is to collect, analyze, and summarize recent
Externí odkaz:
https://doaj.org/article/71df4e4cc33c43158a0b3d473424c03f
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Mitochondrial phosphoenolpyruvate carboxykinase (PCK2), a mitochondrial isoenzyme, supports the growth of cancer cells under glucose deficiency conditions in vitro. This study investigated the role and potential mechanism of PCK2 in the occu
Externí odkaz:
https://doaj.org/article/1da8ea36d59d49958fe3f54e40f9e9c2
Autor:
Jiyue Wu, Feilong Zhang, Xiang Zheng, Dongshan Chen, Zhen Li, Qing Bi, Xuemeng Qiu, Zejia Sun, Wei Wang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Immunotherapy based on immune checkpoint genes (ICGs) has recently made significant progress in the treatment of bladder cancer patients, but many patients still cannot benefit from it. In the present study, we aimed to perform a comprehensi
Externí odkaz:
https://doaj.org/article/da243b06ae9741f6916daa941e6eea5e
Autor:
Fan Pan, Jiajing Liu, Ying Chen, Binghan Zhu, Weiwei Chen, Yuchen Yang, Chunyan Zhu, Hua Zhao, Xiaobei Liu, Yichen Xu, Xiaofan Xu, Liqun Huo, Li Xie, Rui Wang, Jun Gu, Guichun Huang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Treatment of advanced triple-negative breast cancer (TNBC) is a great challenge in clinical practice. The immune checkpoints are a category of immunosuppressive molecules that cancer could hijack and impede anti-tumor immunity. Targeting imm
Externí odkaz:
https://doaj.org/article/d17436e3a4b14ea1afff41f8a3587d6f