Zobrazeno 1 - 10 of 56 pro vyhledávání: '"Immature B-Lymphocyte"'
1
Association of Defective Regulation of Autoreactive Interleukin-6-Producing Transitional B Lymphocytes With Disease in Patients With Systemic Sclerosis
Autor: Sophie Hillion, David Abraham, Voon H Ong, Taher E. Taher, Jacques-Olivier Pers, Jonas Bystrom, Quentin Simon, Christopher P. Denton, Rizgar A. Mageed
Publikováno v: Arthritis & Rheumatology. 70:450-461
Systemic sclerosis (SSc) has the highest case-specific mortality of any rheumatic disease, and no effective therapy is available. A clear manifestation of SSc is the presence of autoantibodies. However, the origin of autoantibody-producing B lymphocy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372e1ef5d89d713451b7cad50f9dcbe9
https://doi.org/10.1002/art.40390
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3
IKKα deficiency disrupts the development of marginal zone and follicular B cells
Autor: Yinling Hu, Mumtaz Yaseen Balkhi, Gábor Wittmann, Jami Willette-Brown
Publikováno v: Genes Immun
Only few genes have been confidently identified to be involved in the Follicular (FO) and Marginal Zone (MZ) B cell differentiation, migration, and retention in the periphery. Our group previously observed that IKKα kinase inactive mutant mice IKKα
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de5b69d3327a61bb9a0bc2097a3047f3
https://europepmc.org/articles/PMC8191388/
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4
Immature Terminal Deoxynucleotidyl Transferase Positive B Cells are Detected in a Subset of Adult and Pediatric Liver Biopsies
Autor: Kwun Wah Wen, Ryan M. Gill
Publikováno v: Applied immunohistochemistrymolecular morphology : AIMM. 27(4)
Terminal deoxynucleotidyl transferase (TdT) is a nuclear enzyme restricted to precursor lymphoid cells and their malignant counterparts; immunohistochemical TdT labeling is helpful in recognition of lymphoblasts, which can resemble mature lymphocytes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114401489856b737e2f8f6952866cb90
https://pubmed.ncbi.nlm.nih.gov/28968264
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5
Alteration of B cell subsets and the receptor for B cell activating factor (BAFF) in paediatric patients with type 1 diabetes
Autor: Adam Klocperk, Anna Sediva, Stanislava Kolouskova, Jan Lebl, Zdenek Sumnik, Barbora Obermannova, Stepanka Pruhova, Irena Zentsova, Jana Sklenarova, Lenka Petruzelkova, Jana Kayserova, Zuzana Parackova, Tomas Kalina, Michal Rataj
Publikováno v: Immunology letters. 189
Background Lately, mounting evidence has shown that B cells play an important role in the pathogenesis of type 1 diabetes (T1D). Here, we present alterations in B cell subsets including BAFF receptor (BAFFR) expression in cohorts of patients with typ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be453d13e42a0be9399d8cb22c93b862
https://pubmed.ncbi.nlm.nih.gov/28414179
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6
Lymphocyte Subpopulations in the Liver, Spleen, Intestines, and Mesenteric Nodes: An Immunohistochemical Study Using Human Fetuses at 15-16 Weeks
Autor: Gen Murakami, Si Eun Hwang, Ji Hyun Kim, Hee Chul Yu, Baik Hwan Cho
Publikováno v: The Anatomical Record. 297:1478-1489
The roles of the liver and intestines in lymphocyte differentiation in human fetuses were assessed by immunohistochemical analysis of the thymus, bone marrow, liver, spleen, intestines, and lymph nodes of 15-16 week human fetuses using primary antibo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c07fabddb1160d79980b4a11895b9fbb
https://doi.org/10.1002/ar.22940
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7
To κ+ B or not to κ+ B
Autor: Craig H. Bassing, Megan R. Fisher
Publikováno v: Nature Immunology. 16:1007-1009
Immature B lymphocytes and T lymphocytes assemble antigen receptor–encoding genes in lineage- and developmental stage–specific fashion. New findings show that pre-B cells use specialized locus-specific epigenetic mechanisms to promote recombinati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7852a94fe0c8d3392c01e9dde97f6bc6
https://doi.org/10.1038/ni.3277
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9
T lymphocytes are necessary for the peripheral phase of B lymphocyte maturation
Autor: Novica M. Milićević
Publikováno v: Srpski arhiv za celokupno lekarstvo. 136:166-170
Until recently, B lymphocyte maturation was considered to be independent of the thymus and T lymphocytes. However, using nude animals, which lack the functional thymus, we have shown that T lymphocytes are required for the peripheral phase of B lymph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662d9bc0cfbf81895ed140e3c1012082
https://doi.org/10.2298/sarh08s2166m
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10
Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansion
Autor: Jacques J.M. van Dongen, Tomasz Szczepański, Menno C. van Zelm, Mirjam van der Burg
Publikováno v: The Journal of Experimental Medicine
Journal of Experimental Medicine, 204(3), 645-655. Rockefeller University Press
The contribution of proliferation to B lymphocyte homeostasis and antigen responses is largely unknown. We quantified the replication history of mouse and human B lymphocyte subsets by calculating the ratio between genomic coding joints and signal jo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a497d00928d3112c0d72160e1f7d291
https://pure.eur.nl/en/publications/a7884192-412d-4e25-89ad-df97c668cb36
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