Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Imma Castaldo"'
Autor:
Antonio Porcellini, Elena Salvatore, Giuseppe De Michele, Simone Migliore, Silvio Peluso, Antonella Romano, Angelo Del Mondo, Candida Zuchegna, Ferdinando Squitieri, Rosella Mechelli, Mariarosaria De Rosa, Enrico V. Avvedimento, Imma Castaldo, Cristiana Borrelli, Silvia Romano, Giovanni Ristori, Luigi Angelo Vescovi
Publikováno v:
Annals of Neurology.
Easily accessible biomarkers in Huntington disease (HD) are actively searched. We investigated telomere length and DNA double-strand breaks (histone variant pγ-H2AX) as predictive disease biomarkers in peripheral blood mononuclear cells (PBMC) from
Autor:
Carmela Romano, Emanuele Morena, Imma Castaldo, Ferdinando Squitieri, A Del Mondo, Giovanni Ristori, Enrico V. Avvedimento, Silvia Romano, Silvio Peluso, Antonio Porcellini, Elena Salvatore, Simone Migliore, Cristiana Borrelli, G. De Michele
Publikováno v:
Wet biomarkers.
Background Blood biomarkers to improve the management of pre-manifest Huntington’s disease (pre-HD) are actively searched We investigated the telomere length (TL) and DNA damage signatures (DDS) in peripheral lymphocytes from pre-HD individuals and
Autor:
Luigi Angelo Vescovi, Rosella Mechelli, Giuseppe De Michele, Imma Castaldo, Candida Zuchegna, Ferdinando Squitieri, Antonella Romano, Enrico V. Avvedimento, Mariarosaria De Rosa, Cristiana Borrelli, Silvio Peluso, Antonio Porcellini, Elena Salvatore, Giovanni Ristori, Angelo Del Mondo, Silvia Romano, Simone Migliore
Publikováno v:
SSRN Electronic Journal.
Background: Blood biomarkers, that may improve the management of the pre−manifest phase of Huntington's disease (PRE−HD), are actively searched. We investigated telomere length (TL) and DNA damage signatures (DDS) as potential predictive biomarke
Autor:
Fabiana Rossi, Luigi Di Maio, Alessandro Filla, Giuseppe De Michele, Imma Castaldo, Elena Salvatore, Valeria Russo Cinzia, Ilaria Giordano, Carlo Rinaldi, Tecla Tucci, Vincenzo Brescia Morra, Sara De Matteis
Publikováno v:
Scopus-Elsevier
Background:The primary aim of the present study was to determine the survival rates and identify predictors of disease duration in a cohort of Huntington's disease (HD) patients from Southern Italy.Methods:All medical records of HD patients followed
Autor:
Luigi Pianese, Michele Pinelli, Fabio Di Marzio, Maria Scarcella, Imma Castaldo, Michele Ragno, Antonella Monticelli, Gabriella Cacchiò, Fabiana Altamura, Francesco Coretti, Serena Silvestri
Publikováno v:
Neurogenetics (Oxf., Print) vol. 12 (2011): 337–343. doi:10.1007/s10048-011-0298-1
info:cnr-pdr/source/autori:Ragno Michele, Pianese Luigi, Pinelli Michele, Silvestri Serena, Cacchio Gabriella, Di Marzio Fabio, Scarcella Maria, Coretti Francesco, Altamura Fabiana, MONTICELLI A, Castaldo Imma/titolo:Shorter telomeres in patients with cerebral autosomal dominant arteriopathy and leukoencephalopathy (CADASIL)/doi:10.1007%2Fs10048-011-0298-1/rivista:Neurogenetics (Oxf., Print)/anno:2011/pagina_da:337/pagina_a:343/intervallo_pagine:337–343/volume:vol. 12
info:cnr-pdr/source/autori:Ragno Michele, Pianese Luigi, Pinelli Michele, Silvestri Serena, Cacchio Gabriella, Di Marzio Fabio, Scarcella Maria, Coretti Francesco, Altamura Fabiana, MONTICELLI A, Castaldo Imma/titolo:Shorter telomeres in patients with cerebral autosomal dominant arteriopathy and leukoencephalopathy (CADASIL)/doi:10.1007%2Fs10048-011-0298-1/rivista:Neurogenetics (Oxf., Print)/anno:2011/pagina_da:337/pagina_a:343/intervallo_pagine:337–343/volume:vol. 12
CADASIL is a hereditary systemic vasculopathy which affects mainly small cerebral arteries and is caused by mutations in the Notch3 gene. Misfolding of Notch3 is linked to endoplasmic reticulum stress and increased reactive oxygen species, which may
Autor:
Rocco Galasso, Emanuela Lapice, Sergio Cocozza, Antonella Monticelli, Imma Castaldo, Olga Vaccaro, Michele Pinelli, Giovanna Donnarumma, Gabriele Riccardi, Manuela Giacchetti, Angela A. Rivellese
Publikováno v:
Diabetes care 30 (2007): 1156–1161. doi:10.2337/dc06-1153
info:cnr-pdr/source/autori:Vaccaro O, Lapice E, MONTICELLI A, Giacchetti M, Castaldo I, Galasso R, Pinelli M, Donnarumma G, Rivellese AA, Cocozza S, Riccardi G./titolo:Pro12Ala polymorphism of the PPAR gamma 2 locus modulates the relationship between energy intake and body weight in type2 diabetic patients./doi:10.2337%2Fdc06-1153/rivista:Diabetes care/anno:2007/pagina_da:1156/pagina_a:1161/intervallo_pagine:1156–1161/volume:30
info:cnr-pdr/source/autori:Vaccaro O, Lapice E, MONTICELLI A, Giacchetti M, Castaldo I, Galasso R, Pinelli M, Donnarumma G, Rivellese AA, Cocozza S, Riccardi G./titolo:Pro12Ala polymorphism of the PPAR gamma 2 locus modulates the relationship between energy intake and body weight in type2 diabetic patients./doi:10.2337%2Fdc06-1153/rivista:Diabetes care/anno:2007/pagina_da:1156/pagina_a:1161/intervallo_pagine:1156–1161/volume:30
OBJECTIVE—We explore the relationship among BMI, habitual diet, and the Pro12Ala polymorphism in the peroxisome proliferator–activated receptor (PPAR)γ2. RESEARCH DESIGN AND METHODS—The Pro12Ala variant was characterized in 343 unrelated type
Publikováno v:
BMC genomics 14 (2013): 692. doi:10.1186/1471-2164-14-692
info:cnr-pdr/source/autori:S Cocozza, G Scala, G Miele, I Castaldo, A Monticelli/titolo:A distinct group of CpG islands shows differential DNA methylation between replicas of the same cell line in vitro./doi:10.1186%2F1471-2164-14-692/rivista:BMC genomics/anno:2013/pagina_da:692/pagina_a:/intervallo_pagine:692/volume:14
BMC Genomics
info:cnr-pdr/source/autori:S Cocozza, G Scala, G Miele, I Castaldo, A Monticelli/titolo:A distinct group of CpG islands shows differential DNA methylation between replicas of the same cell line in vitro./doi:10.1186%2F1471-2164-14-692/rivista:BMC genomics/anno:2013/pagina_da:692/pagina_a:/intervallo_pagine:692/volume:14
BMC Genomics
Background CpG dinucleotide-rich genomic DNA regions, known as CpG islands (CGIs), can be methylated at their cytosine residues as an epigenetic mark that is stably inherited during cell mitosis. Differentially methylated regions (DMRs) are genomic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319117d9d06378a5066e652313b53a41
Autor:
Savina Agnese, Antonella Scorziello, Lucio Annunziato, Imma Castaldo, Annalisa Carlucci, Annagrazia Adornetto, Enrico V. Avvedimento, Alessandra Livigni, Antonio Feliciello, Corrado Garbi
Publikováno v:
Molecular Biology of the Cell. 17:263-271
AKAP121 focuses distinct signaling events from membrane to mitochondria by binding and targeting cAMP-dependent protein kinase (PKA), protein tyrosine phosphatase (PTPD1), and mRNA. We find that AKAP121 also targets src tyrosine kinase to mitochondri
Autor:
Arturo Brunetti, Giuseppe De Michele, Imma Castaldo, Sabina Pappatà, Maria Teresa Pellecchia, Marco Salvatore, Elena Salvatore, Valeria A. Sansone, Andrea Varrone, Giovanni Coppola, Alessandro Filla, Paolo Barone
Publikováno v:
Annals of Neurology. 55:426-430
Degeneration of substantia nigra has been described in spinocerebellar ataxia type 2 (SCA2). In this study, dopamine transporter (DAT) density with [123 I]FP-CIT SPECT was studied in six SCA2 patients with no parkinsonian signs, six Parkinson's disea
Autor:
G. De Michele, Sirio Cocozza, Giuseppina Ruggiero, A. Filla, Giorgio Casari, A. Patrignani, Colin L. Masters, V. Bonavita, Amalia C. Bruni, Imma Castaldo, Giampiero Volpe
Publikováno v:
Scopus-Elsevier
Objective: To perform a clinical and molecular study of a large autosomal dominant family with a complex neurologic syndrome that comprises early-onset dementia, extrapyramidal and cerebellar features, and epilepsy. Background: Early-onset forms of d